Gene Information

Name : VVA1301 (VVA1301)
Accession : NP_937357.1
Strain :
Genome accession: NC_005140
Putative virulence/resistance : Virulence
Product : vulnibactin-specific 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 1440358 - 1441995 bp
Length : 1638 bp
Strand : +
Note : -

DNA sequence : 
ATGAACTCTGTACAATCTGATTTCACTCCATGGCCAGAGCAGATGGCGAACGATTATCGACGCCTTGGCTTATGGCAAGA
TAAAACGCTCTATCAGTATCTCAAGCAATCCATTATTCGCTACCCGACCAATATTGCTATTGTATGCCGTCAACAAAGCA
TCACATACGCTGAGCTGGAGCGAAAAATCCATGCGGCTGCCAATGGGTTTCGCTCGCTGGGCCTCGCTGAAGGCGATAAC
GTGATTCTGCAGATGACCAATATCGCCGAGTTCTATGTCAGTTACTTTGCGTTGATTCATCAAGGCATTCGCCCAATATT
GGCGTTATCTGCCCATCGTCACGCTGAGATTAGCTACTTCTGCCAACATGCCCAAGCCAAAGCGTATCTGATCGATGGCC
AAACTCGTGGTTTTGACTACCAAACGCTGGCCGAAAAACTTCTCAAAGAGCACCCATGTTTGCGCCATGTCATCGTCAGA
GCCAATCACTCCGAGCTGCTGCAATCTCATTTCATCTCATTTGACGACTTTCGCGATGAACGAGAACTGGCCCCTGTCAG
TAACGCAAGTCAGGTTGCCTTTTTTCAACTTTCCGGCGGGACGACGGGCACTCCCAAATTGATCCCACGTACGCACAATG
ATTATGCTTACAGTGTGGTCGGCAGTAACGCCATCTGTGGTTTTAATGAGTACACACGCTATCTTTGCGCGCTACCCGCT
GCGCACAATTTTCCGCTCAGTTCCCCAGGTTCGCTTGGAGTATTTTTCGCTGGTGGCACCGTTGTCCTGACGCAAGACCC
AACGCCCAAAGCGGCATTTCCTCTGATTGAACGTCACAAAGTAACCGTATCGGCTCTGGTTCCCCCGTTAGCTTTGCTGT
GGATGGATGCGGCGCCACACGCACGCTACAACTTATCGAGCTTACAGTTAATCCAAGTTGGTGGTGCTAAGTTGAGCCAA
AGTGCGGCAAAAGCTTTGCCAAAAGCACTCAATTGCCAGCTTCAACAAGTGTTCGGCATGGCAGAAGGGCTAGTGAATTA
TACTCGCCTGGACGATCCGCTGGAGGTGATCATCGAAACGCAAGGTCGGCCCATATCCGCCCATGACCAAGTAAAAGTGG
TCAATGAAGCCGGTGAAGAGGTTGCGTGCGGAGAAGAAGGTTTTCTCCTTACCCAAGGGCCTTATACGATTCGCGGCTAC
TACCGAGCACCGGAGCACAATCAGCGTTCGTTCACTCACAACGGTTTTTATCGCACTGGCGATATTGTGAAGATAACAGA
GCAAGGCAATATCATCGTCACAGGCCGAGACAAAGATCAGATCAATCGTGGCGGTGAAAAAATCGCGGCGGAAGAAGTGG
AGAATCATTTACTGGGCCACAGTGCTATTCATGATGTGGCGTTGATTGCCATTCCCGACCGCTTGTTGGGTGAACGAAGC
TGCGCAGTGATCGTCACCAAACGTCATCTCAATATCACAGGAACGGAACTAAAACGCTACTTACGCAGCAAAGGGTTGGC
GGACTATAAGATCCCCGATGTGATCCAATTTGCCGATACTCTGCCCAAAACATCCGTAGGAAAGGTCGACAAGAAACGCT
TACGTGAATCTTACGCCCAGCTTGGTTTGAGTACTTAG

Protein sequence : 
MNSVQSDFTPWPEQMANDYRRLGLWQDKTLYQYLKQSIIRYPTNIAIVCRQQSITYAELERKIHAAANGFRSLGLAEGDN
VILQMTNIAEFYVSYFALIHQGIRPILALSAHRHAEISYFCQHAQAKAYLIDGQTRGFDYQTLAEKLLKEHPCLRHVIVR
ANHSELLQSHFISFDDFRDERELAPVSNASQVAFFQLSGGTTGTPKLIPRTHNDYAYSVVGSNAICGFNEYTRYLCALPA
AHNFPLSSPGSLGVFFAGGTVVLTQDPTPKAAFPLIERHKVTVSALVPPLALLWMDAAPHARYNLSSLQLIQVGGAKLSQ
SAAKALPKALNCQLQQVFGMAEGLVNYTRLDDPLEVIIETQGRPISAHDQVKVVNEAGEEVACGEEGFLLTQGPYTIRGY
YRAPEHNQRSFTHNGFYRTGDIVKITEQGNIIVTGRDKDQINRGGEKIAAEEVENHLLGHSAIHDVALIAIPDRLLGERS
CAVIVTKRHLNITGTELKRYLRSKGLADYKIPDVIQFADTLPKTSVGKVDKKRLRESYAQLGLST

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-104 47
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 8e-104 47
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-104 47
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 7e-104 47
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-104 47
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-104 47
ybtE CAA21394.1 - Virulence HPI Protein 7e-104 47
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-104 47
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 5e-104 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VVA1301 NP_937357.1 vulnibactin-specific 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 3e-118 49
VVA1301 NP_937357.1 vulnibactin-specific 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 7e-114 48
VVA1301 NP_937357.1 vulnibactin-specific 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 1e-99 43