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Name : leuS (VV0911) Accession : NP_933704.1 Strain : Genome accession: NC_005139 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 913042 - 915615 bp Length : 2574 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAACAATATAATCCACAAGATATTGAACAGAAAGTTCAACAGCACTGGGACAACAACAAAACATTTGTTGTGAC TGAAGATCCAACCAAAGAGAAGTTCTACTGCCTCTCTATGTTCCCATACCCAAGTGGTCGACTGCACATGGGTCACGTGC GTAACTACACCATCGGTGACGTAGTATCTCGTTTCCAACGCCTACAAGGCAAAAACGTCATGCAGCCAATCGGCTGGGAC GCATTCGGTCTACCTGCAGAAAACGCAGCGGTGAAAAACAACACCGCGCCTGCGCCTTGGACTTACGAAAACATCGAATA CATGAAGAACCAACTTAAGCTTCTTGGCTTTGGTTATGACTGGAACCGCGAATTCGCCACTTGTACGCCTGAGTACTACC GTTGGGAACAAGAGTTCTTCACTAAGCTTTACCAGAAAGGTCTGGTTTACAAGAAGACGTCTTCTGTTAACTGGTGTCCA AACGACCAAACTGTTCTTGCGAACGAGCAGGTTGAAGACGGCTGCTGCTGGCGTTGTGATACGCCTGTAGAGCAAAAAGA AATTCCTCAGTGGTTTATCAAGATCACAGAGTACGCTCAAGAACTGCTTGATGATCTAGACACACTTGAAGGCTGGCCAG AAATGGTGAAAACCATGCAACGCAACTGGATTGGTCGTTCTGAAGGTGTGGAGCTAAAGTTTGAAGTGAAAGGTCAACAA GACCTAGAAGTGTACACTACTCGTCCAGACACACTAATGGGTGTGACTTATGTCGGTATCGCAGCAGGTCACCCTCTAGC GAAAATTGCCGCTGAGAATAACCCAGATCTTGCTGCGTTCATCGAAGAATGTAAGAACACCAAAGTTGCTGAAGCTGAAT TGGCCACCATGGAGAAGAAAGGTATGGCGACGGGCCTTACTGCTATTCATCCATTAAACGGCCGTGAAGTGCCAGTGTAC GTCGCTAACTTCGTATTGATGGACTACGGTACAGGCGCTGTTATGGCAGTACCGGCACACGACCAACGTGACTTCGAGTT CGCCACTAAGTACGGTCTAGACATCATTCCGGTAATCAAGCCAATTGATGGCAGCGAGCTAGACATCTCAGAAGCAGCCT ACACAGAGAAAGGCGTGCTGTTCGATTCAGGTGAGTTCGATGGCCTAGAATTCCAAGCAGCGTTCGATGCCATCGCAGCG AAGCTAGAAGCAGAAGGCAAAGGCACTAAGACGGTTAACTTCCGTCTACGTGACTGGGGTGTATCTCGTCAACGTTACTG GGGTGCACCAATCCCAATGGTCACCACTGAAGATGGCCAAGTTCACCCAGTACCCGCAGACCAACTACCCGTGATTCTTC CTGAAGACGTAGTAATGGACGGCGTAACGAGCCCAATCAAAGCCGACAAAGAGTGGGCGAAGACAACCTTCAACGGTGAG CCAGCTCTGCGTGAGACAGACACCTTCGATACCTTTATGGAATCTTCTTGGTACTACGCACGTTACTGTTCACCACAAGC TGACGACATCCTAGATCCAGAAAAAGCCAACTACTGGCTGCCTGTAGACCAATACATCGGCGGTATCGAGCACGCGTGTA TGCATCTATTGTACTCTCGCTTCTTCCACAAACTGCTGCGTGATGCGGGCTACGTGACGTCTGACGAGCCGTTCAAGCAA CTACTGTGTCAAGGCATGGTACTGGCAGATGCTTTCTACTACACCAACGATAAAGGTGGCAAAGAGTGGGTATCACCAAC GGAAGTGAAAGTTGAACGCGATGGCAAAGGTCGCATCACTTCAGCTGTCGACAATGAAGGTCGTAACGTAGAACACTCAG GCATGATCAAAATGTCTAAGTCGAAAAACAACGGTATCGATCCACAAGAGATGGTCGACAAATACGGCGCAGACACAGTA CGTCTATTCATGATGTTTGCTTCTCCAGCAGACATGACACTTGAGTGGCAAGAGTCTGGCGTAGAAGGGGCTAACCGCTT CCTGAAACGTGTTTGGAAACTCGTAAACGAGCACACATCAAAAGGCGCAGCAGAAGCAGTAAATGCAGCAGCACTGTCTG GTGATCAAAAAGCACTGCGTCGTGACGTTCACAAAACCATCGCCAAAGTAACCGATGACGTTGCGCGTCGTCAGACATTC AACACCGCAATCGCTGCGGTCATGGAGTTGATGAACAAGCTGGCGAAAGCGCCACAAGAATCTGCACAAGATCGTGCGAT CCTTGATGAAGCGCTAAAAGCGGTCGTTGCGATGCTGTACCCAATCACTCCGCATATCTGTTTCGAAATGTGGACAGCAC TTGGCCAGCAAGACATCGACAACGCATCTTGGCCAACTTACGATGAGCAAGCTCTGGTTGAAGACGAAAAACTGATTGTT GTTCAAGTAAACGGCAAAGTCCGCGGTAAAATCACCGTTGCTGCAGACGCAACCAAAGAGCAAGTTGAAGAAATTGGTCT TAACGAAGAAAACGTCTCTAAACACCTAGACGGCGTGACTATCCGTAAAGTGATTTACGTACCAGGCAAACTATTGAGCA TCGTGGCGAACTGA Protein sequence : MQEQYNPQDIEQKVQQHWDNNKTFVVTEDPTKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVSRFQRLQGKNVMQPIGWD AFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNREFATCTPEYYRWEQEFFTKLYQKGLVYKKTSSVNWCP NDQTVLANEQVEDGCCWRCDTPVEQKEIPQWFIKITEYAQELLDDLDTLEGWPEMVKTMQRNWIGRSEGVELKFEVKGQQ DLEVYTTRPDTLMGVTYVGIAAGHPLAKIAAENNPDLAAFIEECKNTKVAEAELATMEKKGMATGLTAIHPLNGREVPVY VANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPVIKPIDGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAA KLEAEGKGTKTVNFRLRDWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILPEDVVMDGVTSPIKADKEWAKTTFNGE PALRETDTFDTFMESSWYYARYCSPQADDILDPEKANYWLPVDQYIGGIEHACMHLLYSRFFHKLLRDAGYVTSDEPFKQ LLCQGMVLADAFYYTNDKGGKEWVSPTEVKVERDGKGRITSAVDNEGRNVEHSGMIKMSKSKNNGIDPQEMVDKYGADTV RLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVNEHTSKGAAEAVNAAALSGDQKALRRDVHKTIAKVTDDVARRQTF NTAIAAVMELMNKLAKAPQESAQDRAILDEALKAVVAMLYPITPHICFEMWTALGQQDIDNASWPTYDEQALVEDEKLIV VQVNGKVRGKITVAADATKEQVEEIGLNEENVSKHLDGVTIRKVIYVPGKLLSIVAN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 6e-161 | 44 |
