Gene Information

Name : hemC (VV0081)
Accession : NP_932874.1
Strain :
Genome accession: NC_005139
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 92649 - 93587 bp
Length : 939 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGACACACTCAACGCCAATCCGAATCGCAACACGCAAAAGCCCCCTCGCTCTATGGCAAGCCTACTACGTAAAAGATGC
GCTACAAAAAGCCCATCCGGGCTTAGAAGTCGAGCTGGTGACCATGGTGACCAAAGGCGATGTGATTCTTGATACCCCTC
TTGCCAAAGTGGGTGGCAAAGGCCTTTTTGTCAAAGAGCTCGAAGTGGCAATGCTGGAAGGTCGTGCAGACCTCGCCGTT
CACTCGATGAAAGACGTGCCAGTGGATTTCCCAGAAGGTTTAGGTTTGGTGACGATTTGTGAGCGTGAAGATCCTCGCGA
TGCTTTTGTCTCAAACACCTACCATCATGTTGATGAGCTGCCTCAAGGCGCAGTTGTCGGCACTTGTAGCTTGCGTCGTC
AATGTCAATTGAAAGCCTATCGCCCAGATTTGGTGATCAAAGAACTGCGCGGCAACGTCGGCACTCGTTTAAGCAAACTC
GATGCAGGTGAATACGACGCGATCATTCTCGCGGCCGCTGGCTTGAAACGTCTTGAGCTGGAAGAGCGCATCCGCAGCTT
TATTGAGCCAGAACAATCGCTCCCAGCCGTCGGCCAAGGTGCCGTGGGCATTGAATGTCGTACTAACGATGAGCGTATTC
TCAAACTTCTCGAACCGTTGAACCACGCCGATACGGCCGATCGCGTCAAATGCGAACGCGCCATGAACCTCACCTTAGAA
GGCGGCTGCCAAGTGCCAATCGGTAGCTATGCGCTGCTTGAGGGCGATGAGATCTGGCTACGTGCGTTGGTGGGCGAGCC
AGATGGCAGCGAAATCGTCCGTGGTGAAATTCGTGGCCCTCGCGCGCAGGCGGAACAATTAGGCGTGCAATTGGCCAATC
AACTGCTGGATGAGGGTGCCAGAGAGATCCTCACCAAGTTGTACCAAGACCACGAATAA

Protein sequence : 
MTHSTPIRIATRKSPLALWQAYYVKDALQKAHPGLEVELVTMVTKGDVILDTPLAKVGGKGLFVKELEVAMLEGRADLAV
HSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYHHVDELPQGAVVGTCSLRRQCQLKAYRPDLVIKELRGNVGTRLSKL
DAGEYDAIILAAAGLKRLELEERIRSFIEPEQSLPAVGQGAVGIECRTNDERILKLLEPLNHADTADRVKCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEIRGPRAQAEQLGVQLANQLLDEGAREILTKLYQDHE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-85 62
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-85 62