Gene Information

Name : smpB (VV0818)
Accession : NP_933611.1
Strain :
Genome accession: NC_005139
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 823490 - 823975 bp
Length : 486 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAAAGAAAAATTCAAAACCAAAAGCGGGTAGCAACACTATCGCGCTGAACAAAAAAGCTCGCCACGAATATTTCAT
AGAAGATGAGATTGAAGCAGGCATGGAGCTACAAGGGTGGGAAGTGAAAGCTCTTCGCCAGGGCAAAGCCAATATTTCTG
AAAGTTACGTATTTATGCGTGACGGCGAAGCCTTCGTTAGCGGCATGACTATCACTCCTTTGAATCAAGCGTCGACACAC
GTAGTAGCGAACCCTACCCGTGTGCGAAAACTGCTCATGAGCCGTCGTGAACTTGATAACTTACTCGGACGTATCAACCG
CGAAGGCATGACATTAGCAGCACTTTCACTCTACTGGGCTCGCTCATGGGTGAAGATCAAAATCGGTGTAGCAAAAGGTA
AAAAGCTACACGATAAACGTGATGATATTAAAGATCGCGATTGGCAACGCCAAAAAGCTCGCGTGATGAAGAGTTCACTG
CGTTAA

Protein sequence :
MAKKNSKPKAGSNTIALNKKARHEYFIEDEIEAGMELQGWEVKALRQGKANISESYVFMRDGEAFVSGMTITPLNQASTH
VVANPTRVRKLLMSRRELDNLLGRINREGMTLAALSLYWARSWVKIKIGVAKGKKLHDKRDDIKDRDWQRQKARVMKSSL
R

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-58 84
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 6e-18 42