Gene Information

Name : murD (VV0612)
Accession : NP_933405.1
Strain :
Genome accession: NC_005139
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 596916 - 598244 bp
Length : 1329 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGATCGTTGGCAAGACATCAAACAGGTTGTGGTGGTAGGGCTCGGTATTACTGGGCTCTCCGTCGTTAGACATTTGCG
AAAAACACAGCCGCAGTTGCAAGTGAAAGTGATTGATACGCGTCCAACCCCACCTGGTGTGGAACAATTGCCTCCAGACA
TTGCGCTGCATGTTGGCAGTTGGAATGAAGCTTGGTTAGCTGAGGCTGATTTGGTCGTCACAAACCCAGGCATCGCCTTA
GCGACGCCTCAAATTCAAACGGTGTTAGCACGCGGCGTTGCTGTGGTGGGTGATATCGAGTTGTTCGCTTGGGCGGCAGA
TAAACCCGTCATCGCGATTACTGGCTCAAATGGCAAAAGCACCGTCACGGATTTAACCGGAGTGATGGCTAACGCCTGTG
GGGTGAAATGCGCGATTGGCGGTAACATTGGTGTTCCTGCACTCGATTTGTTGGAGCAAGAGGTTGAGCTTTATGTACTT
GAACTCTCGAGTTTTCAATTAGAGACGACTACCAGTCTCCATTTGGTTGCAGCGGCATTTTTGAACCTTTCTGAAGATCA
CATGGATCGCTACCAAGGCATGGATGACTATCGCCAAGCTAAACTGCGCATCTTTCAGCATGCAAAACATGGTGTCGTGA
ATCGCGATGATCGTCAGACTTATCCTGAAACTTCCCATGGCCAGCAATCACTTGCTTTGGTGACTTTTGGCTCCGATGAC
AAAGAGTTTGGTGTCATGAGTCATCAGGGTGAATCTTGGTTGTCATATAACCAGCAACCTATTTTGGCAAGCCGAGAACT
CAAATTAGTCGGTCAGCACAACGTGGCAAACGTATTGGTGGTTTTGGCGCTGCTGACGTGCGCTGGTATTGATTACCGTA
AAGGCTTGAGCGCTTTGAAGTCTTACACCGGTTTGACACACCGATGTCAGGTTGTCGCAGATAATCGTGGCATCAAGTGG
GTCAATGATTCAAAAGCGACAAATCTTGCTAGTACACAGGCTGCCTTATCGGGGCTTAACTGTGCTGGCAAACTCTACCT
GCTGGTGGGTGGAGATGGCAAAGGGGCTGACTTCTCGCCATTGAAGCCGATTTTGGCGCAGCTAAACCTCCAACTATGTT
GTTTTGGTGCTGATGGTGATCAATTTATGCCATTGCACGCATCGGCCACGCGTTTTGAGCGGATGGAAGATGTGATTGAA
CATATATCTCCACAATTACAATCTGGAGATATGGTGATGCTTTCCCCTGCATGTGCTAGTTTTGACCAATTCAGTAATTT
TATGGCGCGAGGCGATCGATTCGCCGAATTGGCTCGCCAGTATGCATAG

Protein sequence :
MDRWQDIKQVVVVGLGITGLSVVRHLRKTQPQLQVKVIDTRPTPPGVEQLPPDIALHVGSWNEAWLAEADLVVTNPGIAL
ATPQIQTVLARGVAVVGDIELFAWAADKPVIAITGSNGKSTVTDLTGVMANACGVKCAIGGNIGVPALDLLEQEVELYVL
ELSSFQLETTTSLHLVAAAFLNLSEDHMDRYQGMDDYRQAKLRIFQHAKHGVVNRDDRQTYPETSHGQQSLALVTFGSDD
KEFGVMSHQGESWLSYNQQPILASRELKLVGQHNVANVLVVLALLTCAGIDYRKGLSALKSYTGLTHRCQVVADNRGIKW
VNDSKATNLASTQAALSGLNCAGKLYLLVGGDGKGADFSPLKPILAQLNLQLCCFGADGDQFMPLHASATRFERMEDVIE
HISPQLQSGDMVMLSPACASFDQFSNFMARGDRFAELARQYA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 3e-61 44
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 3e-61 44