Gene Information

Name : sirA; uvrY (VV1233)
Accession : NP_934026.1
Strain :
Genome accession: NC_005139
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2197
EC number : -
Position : 1246448 - 1247092 bp
Length : 645 bp
Strand : +
Note : in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate v

DNA sequence : 
TTGATCAATGTTTTCCTTGTAGATGATCACGAGCTGGTTCGCACAGGGATACGACGTATTATTGAAGACGTCCGTGGAAT
GAACGTAGCAGGAGAAGCTGATAGCGGTGAAAATGCGGTAAAATGGTGTCGTAGCAATCATGCAGACGTCGTTTTAATGG
ATATGAACATGCCTGGTATTGGCGGCTTGGAAGCTACCAAGAAAATTTTGCGTGTTAATCCAGATGTAAAAATCATCGTC
TTAACTGTTCATACGGAAAATCCGTTTCCAACTAAAGTGATGCAAGCGGGGGCTTCTGGTTATTTGACCAAAGGCGCTGG
CCCAGATGAAATGGTGAATGCAATTCGTATTGTCCATAGTGGGCAACGTTATATTTCACCAGAAATTGCGCAGCAAATGG
CGTTAAGCCAGTTTTCGCCTGCGTCCGAAAACCCTTTCAAGGATCTGTCTGAGCGTGAGCTTCAGATCATGATGATGATC
ACGAAAGGTCAGAAAGTGACAGATATTTCTGAGCAGTTAAATCTCAGTCCTAAAACTGTCAACAGCTATCGTTATCGTTT
GTTTAGCAAGCTATCGATTAATGGTGACGTAGAGTTGACCCATTTGGCGATTCGCCACGGAATGTTAGATACCGAGACTC
TCTAG

Protein sequence : 
MINVFLVDDHELVRTGIRRIIEDVRGMNVAGEADSGENAVKWCRSNHADVVLMDMNMPGIGGLEATKKILRVNPDVKIIV
LTVHTENPFPTKVMQAGASGYLTKGAGPDEMVNAIRIVHSGQRYISPEIAQQMALSQFSPASENPFKDLSERELQIMMMI
TKGQKVTDISEQLNLSPKTVNSYRYRLFSKLSINGDVELTHLAIRHGMLDTETL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00306 YP_008211632.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR26 Protein 1e-51 51
BJAB07104_00302 YP_008207767.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR25 Protein 1e-51 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sirA; uvrY NP_934026.1 response regulator VFG1889 Protein 8e-55 50