Gene Information

Name : tktA (plu0946)
Accession : NP_928282.1
Strain : Photorhabdus luminescens TTO1
Genome accession: NC_005126
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1088144 - 1090138 bp
Length : 1995 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGACCACTCGTAAAACCCTTGCTAATGCTATTCGCTTCCTGAGCATGGATGCTGTGCAGAAAGCAAAATCAGGGCACCC
TGGTGCACCTATGGGAATGGCGGATATCGCTGAAGTTTTATGGCGTGATTATTTGAATCATAACCCAACTGATCCACATT
GGGTCGATCGTGATCGTTTTGTATTGTCTAACGGTCATGGTTCTATGCTGATTTATAGTCTGTTGCATCTCACCGGTTAT
GATGTTTCAGTCGATGATCTGAAAAATTTCCGTCAGTTACACTCTAAAACCCCAGGCCATCCTGAGTATGGCTATACTCC
AGGCGTAGAAACTACGACAGGTCCTTTAGGGCAGGGGATTGCCAACGCAGTCGGTTTTGCGATTGCTGAACGCACTCTGG
CCGCGCAATTTAACCGTCCTGGTCATGAGATCGTTGACCATAATACTTATGTCTTTATGGGTGATGGCTGCATGATGGAG
GGCATTTCTCATGAAGTTTGCTCTCTGGCGGGAACGTTAAAGTTAGGCAAGTTGGTTGCTTTCTATGATGACAATGGCAT
TTCCATTGATGGTCATGTTGAAGGCTGGTTTACGGATGATACGGCAAGCCGTTTTGAGGCGTATGGCTGGCATGTGATTC
GCGGTGTTGATGGTCATAATGCAGATTCAGTTAAAGCTGCTATCGAAGAAGCACGTAAAGTGACGGATAAACCTTCTCTG
TTAATGTGCAAAACGATTATCGGTTTTGGTGCGCCAACCAAAGCGGGTACCCATGATTCTCATGGCGCGCCATTGGGTGA
TGCGGAAATTGCTGCGACTCGTGAAGCACTCGGTTGGAATTATCCGGCATTTGAAATTCCAGCGGAAATCTATTCTGAGT
GGGATGCCAAAGAAGCTGGCAATGTGAAACAAGCCGCTTGGAATGAAAAATTCGCTGCCTATGAAAAGGCGTATCCTGAA
TTAGCGGCTGAATTTAAACGTCGTACCAGTGGTGAGTTACCGGCAAACTGGGAAGTTGAATCAAAAGCATTTATCGAACA
GTTGCAAAAAAATCCAGCCAATATTGCCAGTCGTAAAGCATCTCAGAATGCCTTGGAAGCTTTTGGTAAGGTGTTGCCTG
AATTTATGGGGGGATCTGCTGATTTGGCACCAAGTAACCTCACGATGTGGTCAGGTTCTAATCCGTTGAACGAAGATCAG
GCAGGTAATTATATCCATTATGGTGTTCGTGAATTTGGCATGTCAGCCATTATGAATGGTATCGCTCTGCATGGTGGTTT
TGTGCCTTATGGTGCAACCTTCCTGATGTTCGTTGAATATGCCCGTAACGCCGTGCGTATGGCGGCATTGATGAAAATTC
GCAGCATCTTTGTTTATACCCATGACTCAATTGGTTTGGGTGAAGATGGTCCGACTCACCAGCCAGTAGAACAGCTCGCC
AGTTTGCGTGTGACGCCAAATTTGAGCACATGGCGTCCATGTGACCAGGTTGAATCTGCGGTGGCGTGGAAATACGCTAT
CGATCGTAAAGCAGGTCCATCAGCACTTATTTTCTCTCGTCAGAATCTGGCACAGCAAGAACGTACTGCTGAGCAGTTGG
CTAATATCGAGAAAGGGGCTTACATCCTGAAAGATTGTCAGGGGCAACCAGAACTGATTTTGATCGCAACGGGTTCAGAA
ATTGAATTGGCGGTGAGTGCTTACCACCAATTGACTGAGGAAGGTCGTCAGGTGCGCGTAGTCTCAATGCCGTCTACTGA
TGCTTTTGATAAGCAAGATGCTGCATACCGAGAAGCGGTTCTGCCTGCTGCGGTTTCTGCACGTGTTGCAGTCGAAGCGG
GTATCGCCGATTACTGGTTTAAATATGTCGGTATGAATGGCGCTATCGTTGGTATGGATACATTTGGTGAGTCAGCACCT
GCTGATCAGTTGTTTAAAACGTTTGGTTTCACTGTAGAGAATGTGGTCGCTAAGGCTAAAGCTTTGCTGAAATAA

Protein sequence :
MTTRKTLANAIRFLSMDAVQKAKSGHPGAPMGMADIAEVLWRDYLNHNPTDPHWVDRDRFVLSNGHGSMLIYSLLHLTGY
DVSVDDLKNFRQLHSKTPGHPEYGYTPGVETTTGPLGQGIANAVGFAIAERTLAAQFNRPGHEIVDHNTYVFMGDGCMME
GISHEVCSLAGTLKLGKLVAFYDDNGISIDGHVEGWFTDDTASRFEAYGWHVIRGVDGHNADSVKAAIEEARKVTDKPSL
LMCKTIIGFGAPTKAGTHDSHGAPLGDAEIAATREALGWNYPAFEIPAEIYSEWDAKEAGNVKQAAWNEKFAAYEKAYPE
LAAEFKRRTSGELPANWEVESKAFIEQLQKNPANIASRKASQNALEAFGKVLPEFMGGSADLAPSNLTMWSGSNPLNEDQ
AGNYIHYGVREFGMSAIMNGIALHGGFVPYGATFLMFVEYARNAVRMAALMKIRSIFVYTHDSIGLGEDGPTHQPVEQLA
SLRVTPNLSTWRPCDQVESAVAWKYAIDRKAGPSALIFSRQNLAQQERTAEQLANIEKGAYILKDCQGQPELILIATGSE
IELAVSAYHQLTEEGRQVRVVSMPSTDAFDKQDAAYREAVLPAAVSARVAVEAGIADYWFKYVGMNGAIVGMDTFGESAP
ADQLFKTFGFTVENVVAKAKALLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 97
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 70