Gene Information

Name : thiC (plu0486)
Accession : NP_927839.1
Strain : Photorhabdus luminescens TTO1
Genome accession: NC_005126
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 524964 - 526901 bp
Length : 1938 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTCATAATACTGTTATCCCTACAACCGATATTTCACCAAAACCCGATCCGGCACGCCCACGTAAAGCTCAACGCGA
TGCCGCCCAAGAATTTATTAATTCTATTCAAGGCGTGACCTTCCCAAATTCACGACGAATTTATCTTCAAGGTTCCCGTG
ACGATATCCAAGTTCCAATGCGTGAAATTCAATTATCTCCCACGTTAATTGGTGGCACCAAAGAAGAACCTCAGTATGAA
GAAAACGAAGCCATTCCGGTTTATGATACTTCCGGCGCTTATGGCGATCCTGATGCCAAGCTGGATGTACATGTTGGGTT
AACTCAACTACGTCAACCCTGGATCGACGAACGCCAAGATACTGAACCTGTTGCCGCCCTCAGCTCCGATTTTACTCAGC
AACGCCTGACGGATGCCGGTCTCGATCATTTACGTTTCAATCATCGCCCCCATCCATTAAAAGCCCGTAAAGACAAACGC
GTTACTCAACTGCACTATGCTCGTCAAGGCATCATCACGCCGGAAATGGAATTTATCGCACTACGGGAAAATATGGGACG
TGAACGTATCCGCGGTGATGTGTTACGCCAACAACATCCCGGACAAAGTTTTGGCGCTCAGTTGCCGGAAAATATCACAC
CAGAATTTGTCCGTCAGGAAGTCGCGGCTGGTCGGGCAATTATCCCTGCCAATATCAATCATCCTGAATCAGAACCGATG
ATTATTGGTCGCAATTTTCTGGTGAAGGTTAACGCCAATATCGGTAATTCTTCAGTCACCTCTTCGATTGAGGAAGAAGT
AGAAAAGTTAATCTGGTCCACTCGTTGGGGCGCAGATACGGTAATGGATCTCTCCACTGGCCGTTATATCCACGAAACCC
GCGAATGGATCTTACGTAACAGCCCGGTTCCTATCGGTACAGTCCCTATTTATCAGGCACTGGAGAAAGTCAATGGCGGG
GCGGAAAATCTCACTTGGGAAATATTCCGTGATACCTTGCTGGAACAAGCAGAACAAGGGGTCGATTACTTCACCATTCA
TGCCGGCGTATTACTGCGCTATGTACCGATGACCGCCAAACGCCTTACTGGGATCGTTTCCCGCGGCGGTTCAATTATGG
CGAAATGGTGTCTGTCTCATCATCAAGAAAACTTTCTCTACCAACATTTCCGTGAAATTTGTGAAATCTGCGCCGCTTAT
GATGTTTCCCTATCATTGGGAGACGGTCTACGCCCCGGTTCTATTCAGGATGCTAACGATGAAGCGCAGTTTGCAGAACT
ACATACATTAGGTGAACTGACCAAAATTGCCTGGGAATATGATGTTCAAGTGATGATCGAAGGCCCCGGGCATATTCCTA
TGCAGATGATCCGCCGCAATATGACGGAAGAATTAGAACATTGTCATGAAGCGCCTTTCTATACTCTTGGCCCCCTGACA
ACAGATATTGCACCCGGTTATGACCACTTCACTTCCGGTATTGGTGCAGCCATGATTGGCTGGTTTGGCTGCGCCATGCT
CTGTTATGTGACGCCGAAAGAGCATCTCGGCTTGCCAAACAAAGATGATGTTAAGCAAGGGCTGATTACCTACAAAATTG
CTGCTCACGCCGCCGATCTCGCCAAAGGTCACCCAGGCGCACAAATCCGCGATAACGCCATGTCTAAAGCACGTTTTGAG
TTCCGTTGGGAAGATCAATTTAATCTCGCGCTCGATCCCGATACTGCTCGCGCCTATCACGATGAAACCTTGCCACAAGC
CTCCGGCAAAATTGCGCATTTCTGTTCTATGTGCGGGCCTAAATTCTGCTCTATGAAGATTTCTCAAGAAGTACGCGATT
ATGCCGCTGGTATGGAACAGATGTCCGAAGCATTCCGCGCCCACGGTAGTGAGTTGTATCACAGTGTAGAGGATGTATCC
CATGAACAATCTGCCTAA

Protein sequence :
MSHNTVIPTTDISPKPDPARPRKAQRDAAQEFINSIQGVTFPNSRRIYLQGSRDDIQVPMREIQLSPTLIGGTKEEPQYE
ENEAIPVYDTSGAYGDPDAKLDVHVGLTQLRQPWIDERQDTEPVAALSSDFTQQRLTDAGLDHLRFNHRPHPLKARKDKR
VTQLHYARQGIITPEMEFIALRENMGRERIRGDVLRQQHPGQSFGAQLPENITPEFVRQEVAAGRAIIPANINHPESEPM
IIGRNFLVKVNANIGNSSVTSSIEEEVEKLIWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGG
AENLTWEIFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAY
DVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHIPMQMIRRNMTEELEHCHEAPFYTLGPLT
TDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFE
FRWEDQFNLALDPDTARAYHDETLPQASGKIAHFCSMCGPKFCSMKISQEVRDYAAGMEQMSEAFRAHGSELYHSVEDVS
HEQSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 68