Gene Information

Name : sctN (plu3767)
Accession : NP_930973.1
Strain : Photorhabdus luminescens TTO1
Genome accession: NC_005126
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 4434397 - 4435719 bp
Length : 1323 bp
Strand : +
Note : Similar to Yops secretion ATPase

DNA sequence :
ATGAAGCTTTCCCTTGACCATATTCCCGGCAAAATGCGCCACGCCATTAATGAATGCCGGCTAATTCAGATTCGTGGCCG
GGTTACTCAGGTCACGGGTACACTCCTTAAAGCCGTTATTCCTGGTGTGCGGATAGGCGAACTTTGTCACTTACGCAATC
CTGACAACACACTGTCGCTTTTGGCGGAGGTGATTGGATTCCAACAACATCAAGCCTTGTTGACTCCACTTGGTGAAATG
TTTGGTATCTCTTCAAATACTGAAGTAAGCCCAACCGGAGCCATGCACCAAGTTGGCGTGGGTGATTATCTGTTAGGGCA
AGTCCTTGATGGGCTAGGTAATCCATTTTCCGGCGGCCAATTGCCGGAACCACAAGCTTGGTATCCCGTTTATCGGGATG
CGCCGGCTCCGATGAGTCGTAAACGGATTGAACACCCGCTTTCACTCGGTGTACGCGCTATTGATGGCTTACTCACTTGT
GGCGAAGGTCAACGTATGGGGATTTTTGCCGCAGCGGGTGGCGGAAAAAGTACCCTGCTATCTACGCTGATTCGTAGCGC
CGAAGTTGATGTTACCGTGCTGGCGCTCATCGGTGAACGTGGCCGTGAAGTACGGGAATTTATCGAATCAGATCTCGGTG
AAGAGGGACTAAAACGTTCCGTGCTGGTGGTAGCGACCTCAGATCGCCCGGCAATGGAGCGAGCTAAAGCAGGGTTTGTC
GCCACATCAATCGCTGAATATTTTCGTGATCAAGGCAAACGTGTACTCCTACTGATGGATTCAGTGACCCGTTTTGCCCG
AGCGCAACGAGAAATAGGTTTAGCTGCCGGCGAGCCGCCAACCCGACGAGGTTATCCCCCATCAGTGTTTGCCGCTTTGC
CACGGCTAATGGAACGTGCTGGTCAATCCGACAAAGGTTCGATTACCGCCCTCTATACCGTCTTGGTGGAAGGCGATGAC
ATGACAGAGCCTGTGGCAGACGAGACTCGTTCTATCCTTGATGGTCACATTATTTTGTCACGCAAACTGGCGGCGGCTAA
CCACTATCCAGCTATCGATGTGTTACGTTCCGCCAGCAGGGTGATGAATCAAATTATCACTCCTGAGCATCAGGCTCAGG
CCGGCCTGTTGCGCAAATGGCTAGCTAAATATGAAGAAGTTGAGCTTTTGTTGCAGATTGGAGAGTACCAAAAAGGGCAA
GATCCCGTTGCTGACAATGCCATTGCACACATTGAAGCAATACGTAACTGGTTACGCCAAGGCACCCATGAGCCAAGTGA
TCTACCGCAAACCTTAGCTCAATTACAGCAGATAACAAAATAA

Protein sequence :
MKLSLDHIPGKMRHAINECRLIQIRGRVTQVTGTLLKAVIPGVRIGELCHLRNPDNTLSLLAEVIGFQQHQALLTPLGEM
FGISSNTEVSPTGAMHQVGVGDYLLGQVLDGLGNPFSGGQLPEPQAWYPVYRDAPAPMSRKRIEHPLSLGVRAIDGLLTC
GEGQRMGIFAAAGGGKSTLLSTLIRSAEVDVTVLALIGERGREVREFIESDLGEEGLKRSVLVVATSDRPAMERAKAGFV
ATSIAEYFRDQGKRVLLLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFAALPRLMERAGQSDKGSITALYTVLVEGDD
MTEPVADETRSILDGHIILSRKLAAANHYPAIDVLRSASRVMNQIITPEHQAQAGLLRKWLAKYEEVELLLQIGEYQKGQ
DPVADNAIAHIEAIRNWLRQGTHEPSDLPQTLAQLQQITK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 0.0 98
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-117 61
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-117 61
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-117 61
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-114 60
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-115 60
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-115 60
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-113 60
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-113 60
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-114 60
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-102 56
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-103 55
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-103 55
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-103 55
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-104 55
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-104 55
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 8e-95 54
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 7e-97 53
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-97 53
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-97 53
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-98 53
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 5e-91 52
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 6e-108 52
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-92 52
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-92 52
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-96 52
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-96 52
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-101 51
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 9e-102 51
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 5e-102 51
unnamed AAL06369.1 EscN Virulence LEE Protein 8e-96 51
escN AAL57542.1 EscN Virulence LEE Protein 5e-97 51
escN AAC31513.1 L0034 Virulence LEE Protein 3e-96 51
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-96 51
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-96 51
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-96 51
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-97 51
escN AAC38383.1 EscN Virulence LEE Protein 2e-96 51
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-96 51
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 6e-97 51
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-97 51
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-97 51
escN AAK26715.1 EscN Virulence LEE Protein 5e-97 51
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-86 47
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-84 46
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-84 46
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-84 46
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-84 46
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 9e-83 45
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 9e-85 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sctN NP_930973.1 type III secretion system ATPase VFG0390 Protein 3e-178 86
sctN NP_930973.1 type III secretion system ATPase VFG0192 Protein 3e-177 83
sctN NP_930973.1 type III secretion system ATPase VFG0048 Protein 6e-137 64
sctN NP_930973.1 type III secretion system ATPase VFG0515 Protein 1e-103 55
sctN NP_930973.1 type III secretion system ATPase VFG2144 Protein 8e-113 54
sctN NP_930973.1 type III secretion system ATPase VFG0812 Protein 1e-96 51
sctN NP_930973.1 type III secretion system ATPase VFG0730 Protein 1e-96 51
sctN NP_930973.1 type III secretion system ATPase VFG0555 Protein 1e-84 46
sctN NP_930973.1 type III secretion system ATPase VFG2459 Protein 9e-88 46
sctN NP_930973.1 type III secretion system ATPase VFG1254 Protein 1e-85 46
sctN NP_930973.1 type III secretion system ATPase VFG2499 Protein 1e-75 46
sctN NP_930973.1 type III secretion system ATPase VFG2331 Protein 2e-76 45
sctN NP_930973.1 type III secretion system ATPase VFG1778 Protein 5e-84 45
sctN NP_930973.1 type III secretion system ATPase VFG1008 Protein 3e-80 42