Gene Information

Name : murD (plu3656)
Accession : NP_930864.1
Strain : Photorhabdus luminescens TTO1
Genome accession: NC_005126
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 4304599 - 4305909 bp
Length : 1311 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGCGGATTATTTGGGTAAAAAAGTCGTCATTATCGGGTTGGGGCTGACGGGTCTCTCCTGTGTTGACTTTTTTATGGC
ACGAGGCGTGATCCCTCGTGTGATGGATACTCGTACGGCACCACCCGGCAAGGATAAACTGCCCGATGGTGTTGAGTGTC
ACAGTGGAAGCCTGAATGCTGACTGGTTGATGGATGCTGATTTGATTGTCGTAAGCCCGGGCATTGCCTTGGCAACGGCG
GTATTGCAGGCTGCGGCTAATGCAGGTATTGAAATTGTTGGTGATATCGAGTTGTTTTGCCGTGAAGCAACAGCCCCGAT
AGTCGCCATTACCGGTTCTAATGGTAAAAGTACTGTTACCAGTCTTGTCGGTGAAATGGCGAAAGCGGCTAATTGGCAGG
TGGGTGTTGGCGGTAATATTGGCCTACCTGCATTAGAATTGTTGAAGAAATCTTGTCAGCTTTATGTCTTAGAGCTCTCC
AGTTTCCAGTTGGAAACTACATATAGCCTGAACGCAACAGCCGCCGCTGTGCTTAATGTAACTGAGGACCATATGGATCG
TTATCCTCAGGGGGTATCTCAGTACCGGGCGGCTAAACTGAGGATTTATCATCAGGCGAAAAGATGCATTGTGAATGCTC
AAGATCCCCTGACACTGCCTGAAATGGGTATGGATAGCCGTTGTGTCAGCTTTGGTGTCGATTGTGGTGACTACCAGCTT
GATAGTGAAAATGCTTTTTTGAAAGTTCACAACCAATCACTGCTGGCGACAAATGAAATTAAGCTGACTGGACGACATAA
CTACGCCAATGGGTTGGTTGCATTGGCTTTAGCTGATGCGGTTGGTATTCCTCGTGAAGCCAGTTTGGCAACATTGACGG
TTTATCCGGGGCTTGACCATCGTTTCCAGCTTGCTCGTTTGAACAAAGGAGTGCGTTGGATTAACGATTCTAAGGCGACC
AATGTTGGCAGTACGATGGCGGCGCTTGATGGTCTGAATCTGGAGGGAACGCTTTATTTGCTGTTAGGTGGTGATGGCAA
GTCGGCAGACTTTTCTCCGCTTAAACCTTTCCTTTGTGGGAATAAAGTTCAGCTTTACTGCTTTGGTCGAGATGGAAAAC
AGTTGGCGCAACTACGCCCGGAAATAGCGACATTGACCGAAACTATGGAACAGGCGATACGTGATATTGCTCCGCGTCTG
GTGGCTGGCGACATGGTGTTGTTATCTCCTGCTTGTGCAAGCCTTGATCAGTTTCGTAATTTTGAACAGCGTGGTCATGA
GTTTACCCGTTTGGCAGAGGAGTTGGGCTGA

Protein sequence :
MADYLGKKVVIIGLGLTGLSCVDFFMARGVIPRVMDTRTAPPGKDKLPDGVECHSGSLNADWLMDADLIVVSPGIALATA
VLQAAANAGIEIVGDIELFCREATAPIVAITGSNGKSTVTSLVGEMAKAANWQVGVGGNIGLPALELLKKSCQLYVLELS
SFQLETTYSLNATAAAVLNVTEDHMDRYPQGVSQYRAAKLRIYHQAKRCIVNAQDPLTLPEMGMDSRCVSFGVDCGDYQL
DSENAFLKVHNQSLLATNEIKLTGRHNYANGLVALALADAVGIPREASLATLTVYPGLDHRFQLARLNKGVRWINDSKAT
NVGSTMAALDGLNLEGTLYLLLGGDGKSADFSPLKPFLCGNKVQLYCFGRDGKQLAQLRPEIATLTETMEQAIRDIAPRL
VAGDMVLLSPACASLDQFRNFEQRGHEFTRLAEELG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 7e-55 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 7e-55 43