Gene Information

Name : guaA (plu2712)
Accession : NP_929946.1
Strain : Photorhabdus luminescens TTO1
Genome accession: NC_005126
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3213917 - 3215494 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAACTAATATCCATCAGCACCGCATTCTTATCCTTGATTTTGGTTCGCAATATACTCAATTGATTGCTCGCCGTAT
CCGTGAAATCGGGGTTTATTGTGAACTTTGGGCATGGGATGTCACTGAAGAGCAAATCCGCGAATTTAACCCAAGCGGCA
TTATTCTTTCCGGTGGCCCGGAAAGTACCACAGCACAAGGAAGTCCACGTGCTCCTGAATATGTTTTCAACGCTGGCGTT
CCGGTTCTGGGGGTCTGCTATGGCATGCAAACGATGTCAGTACAGTTTGGTGGTAAGGTAGAAGATTCTACTGAGCGTGA
ATTTGGGTATGCTCAGGTTGAGATTAAAGCGGAAAGTGCATTATTCCGTGGGATCCAAGATTCATTAAATGAGCAAGGTA
AACCATCATTGGATGTATGGATGAGTCACGGTGATAAAGTTACTGCAATTCCCGAGGACTTTATCACTATCGCCAGCACT
GATACCTGTCCATTTGCCATCATAGCAAATGAAGAAAAACGTTTTTATGGCGTGCAATTCCACCCGGAAGTCACTCATAC
CCATCAGGGACAGCGTATATTGGAACGTTTTGTACTGGATGTATGCCAATGTGAAGCGTTGTGGACGCCTGCTTCTATTA
TCGAAGATACCGTTGTACGCCTGCGTGAACAGGTTGGTGAGGATCACGTTATTTTGGGGCTGTCCGGTGGTGTTGATTCC
TCTGTCACTGCATTGTTACTGCATCGTGCAATTGGTAACCGCCTGACCTGTGTATTTGTTGATAATGGTTTACTGCGTTT
GAATGAAGCCACTCAAGTGATGGAAATGTTTGCCGGCAAATTTGGACTGAATATTGTTCATGTTCCCGCAGAAGATCGCT
TCCTGACTGCACTGGCTGGCATTAATGATCCGGAAGAGAAGCGTAAAACAATTGGCCGTGTGTTTGTTGAAGTCTTTGAT
GAAGAGGCGAGCAAACAGGCTCAGGTTAAATGGCTGGCACAAGGCACTATTTACCCAGATGTTATCGAATCAGCGGCATC
TGCGACCGGCAAAGCACACGTTATCAAATCTCATCATAACGTAGGTGGTTTGCCGGAAGAGATGAAATTGGGTCTGGTGG
AACCGCTGAAAGAGTTGTTCAAAGATGAAGTACGTAAAATTGGTTTGGAATTGGGATTGCCTTATGACATGTTGAACCGT
CATCCATTCCCAGGCCCAGGTTTGGGCGTTCGTGTACTGGGTGAAGTGAAGAAAGAGTACTGCGATCTGTTACGGCAGGC
TGATGCTATTTTCATCGAAGAGCTGCACAAAGCTGATTTGTACAATAAAGTCAGTCAGGCGTTTACCGTATTCTTGCCAG
TTCGCTCCGTGGGTGTGATGGGGGATGGTCGTAAATATGACTGGGTTGTTTCGTTGCGAGCAGTAGAAACGATTGATTTT
ATGACCGCACATTGGGCGCATTTACCATACGATTTCCTAGGCCGGGTTTCTAACCGGATCATCAATGAAGTCAATGGGAT
ATCAAGAGTTGTCTATGATGTCAGCGGCAAACCACCTGCGACTATTGAGTGGGAATGA

Protein sequence :
MTTNIHQHRILILDFGSQYTQLIARRIREIGVYCELWAWDVTEEQIREFNPSGIILSGGPESTTAQGSPRAPEYVFNAGV
PVLGVCYGMQTMSVQFGGKVEDSTEREFGYAQVEIKAESALFRGIQDSLNEQGKPSLDVWMSHGDKVTAIPEDFITIAST
DTCPFAIIANEEKRFYGVQFHPEVTHTHQGQRILERFVLDVCQCEALWTPASIIEDTVVRLREQVGEDHVILGLSGGVDS
SVTALLLHRAIGNRLTCVFVDNGLLRLNEATQVMEMFAGKFGLNIVHVPAEDRFLTALAGINDPEEKRKTIGRVFVEVFD
EEASKQAQVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPEEMKLGLVEPLKELFKDEVRKIGLELGLPYDMLNR
HPFPGPGLGVRVLGEVKKEYCDLLRQADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-129 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-129 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-129 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-115 48