Gene Information

Name : tpx (plu2579)
Accession : NP_929814.1
Strain : Photorhabdus luminescens TTO1
Genome accession: NC_005126
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 3021457 - 3021960 bp
Length : 504 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGACACAAACAGTAAAATTTCAAGGCAATGATATCTCCGTAAGCGGCCAGTTCCCAAAATCAGGGGAAAAAGCGCAAGA
TTTTACTCTGACAGCCAAAGATCTCTCCGATGTCTCTCTTAGCCACTATGCCGGAAAGCGTAAAGTGCTGAATATTTTCC
CAAGTATCGATACCGGTGTTTGTGCGGCATCAGTACGCAAATTTAATCAGGTAGCGAGTGATTTGGAAAATACCGTCGTA
CTGTGCATTTCTGCCGACCTGCCTTTTGCTCAGTCCCGTTTCTGTGGTGCGGAAGGGTTATCAAATGTCGTCACGCTGTC
TACCCTGCGTGGCGGTACTTTCAGTGAAGATTATGGCGTTGCCATCAGCGGTAGTCCTCTGAGTGGTCTCACAGCCCGTG
CAGTCATTGTGCTTGATGAAAGCGATAACGTGATTTATAGCCAACTGGTTGATGAAATCACTAATGAGCCAGATTACGAT
AGCGCACTGGCCGCACTGAAATAA

Protein sequence : 
MTQTVKFQGNDISVSGQFPKSGEKAQDFTLTAKDLSDVSLSHYAGKRKVLNIFPSIDTGVCAASVRKFNQVASDLENTVV
LCISADLPFAQSRFCGAEGLSNVVTLSTLRGGTFSEDYGVAISGSPLSGLTARAVIVLDESDNVIYSQLVDEITNEPDYD
SALAALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-36 50
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 2e-36 50
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-36 50
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 3e-36 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx NP_929814.1 thiol peroxidase VFG0087 Protein 5e-37 50