Gene Information

Name : pykA (plu2118)
Accession : NP_929378.1
Strain : Photorhabdus luminescens TTO1
Genome accession: NC_005126
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2501444 - 2502886 bp
Length : 1443 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGTCCAGACGGCTCAGAAGAACTAAGATTGTTACTACACTTGGTCCGGCTACCGACCGCGATAATAATCTTGAAAAGAT
TATTGCTGCGGGTGCAAACGTAGTCCGCCTTAACTTTTCCCACGGTACCGCCGAAGATCATCTCCAGCGAGCCAGCAAAG
TCCGCGAGATTGCAGCCCGCCTGGGGTGCCATGTCGCTATTCTTGGCGATCTTCAAGGACCTAAAATCCGCGTATCAACG
TTTAAAGAGGGCAAAATTTTCCTGAATATCGGAGATAAATTTCTCCTTGATGCCAATCTTGGTAAAGGCGAAGGCGATAA
GGAGAAAGTCGGTATCGATTACAAAGGACTACCCACGGATGTTGTACCGGGCGATATTTTGTTGCTGGATGACGGACGTG
TTCAACTCAAAGTATTAGACGTTCAGGGAATGAAAGTCTTCACGGAAGTCACTGTAGGCGGCCCGCTATCTAACAATAAA
GGCATTAACAAACTGGGTGGTGGATTATCCGCAGAAGCCCTAACTGAAAAAGATAAAGAAGATATTATTACGGCGGCCAG
AATCGGCGTTGATTACCTTGCCGTCTCTTTCCCTCGCACCGGTGAAGATCTTAACTATGCCCGCCGTCTGGCACGAGACG
CAGGCTGTGAAACGCAGATCGTGGCAAAAGTTGAACGCGCAGAAGCCGTTAGCAGTGATAAAACCATCGATGAAATCATT
CTGGCTTCTGATGTGGTCATGGTTGCCCGTGGTGACCTTGGCGTAGAAATCGGCGATCCAGAGTTAGTTGGCGTTCAGAA
AAAATTAATTCGCCGTGCCCGCCAGCTAAATCGTGTAGTTATTACCGCGACCCAGATGATGGAATCTATGATCACCAATC
CAATGCCCACCCGTGCAGAAGTGATGGATGTGGCAAATGCCGTTCTCGACGGTACTGACGCCGTAATGCTCTCCGCTGAA
ACCGCAGCGGGCCAATACCCTGCCGAAACCGTTGCCGCAATGGCACGAGTCTGTCTCGGAGCAGAAAAAATGCCTGGCCT
CAACGTATCAAAACATCGGCTAGACACAATTTTTGACAGTATTGAAGAAGCCATTGCGATGTCTACCATGTACGCGGCAA
ACCACTTAAATGGAGTTAAAGCCATTATTGCCATGACCGAATCAGGCCGCACCACTCGCATCATGTCTCGCATTAGTTCT
GGTCTCCCGATATTCTCTATGTCCCGTCATGAGAAAACCTTAAACCAAACGGCACTTTACCGTGGCGTTACACCGGTTTA
TTGCAGTAGTCATACTGACGGCATTACGGCGGCCAATGAAGCAGTTAATCGCCTGCGTGATAAAGGTTATCTAGTTTCCG
GTGATCTTGTTCTGGTTACTCAGGGTGATCAGATGGGGACGATTGGCAGTACTAACACCTGCCGTATTCTTGAAGTGGAA
TAA

Protein sequence :
MSRRLRRTKIVTTLGPATDRDNNLEKIIAAGANVVRLNFSHGTAEDHLQRASKVREIAARLGCHVAILGDLQGPKIRVST
FKEGKIFLNIGDKFLLDANLGKGEGDKEKVGIDYKGLPTDVVPGDILLLDDGRVQLKVLDVQGMKVFTEVTVGGPLSNNK
GINKLGGGLSAEALTEKDKEDIITAARIGVDYLAVSFPRTGEDLNYARRLARDAGCETQIVAKVERAEAVSSDKTIDEII
LASDVVMVARGDLGVEIGDPELVGVQKKLIRRARQLNRVVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAE
TAAGQYPAETVAAMARVCLGAEKMPGLNVSKHRLDTIFDSIEEAIAMSTMYAANHLNGVKAIIAMTESGRTTRIMSRISS
GLPIFSMSRHEKTLNQTALYRGVTPVYCSSHTDGITAANEAVNRLRDKGYLVSGDLVLVTQGDQMGTIGSTNTCRILEVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 6e-79 50
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-55 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-55 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-55 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA NP_929378.1 pyruvate kinase VFG0479 Protein 2e-55 41