Gene Information

Name : kdsB (plu1634)
Accession : NP_928922.1
Strain : Photorhabdus luminescens TTO1
Genome accession: NC_005126
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1951447 - 1952196 bp
Length : 750 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGTTCACTGTTATTATTCCTGCTCGCTTTGCTTCAACCCGTTTACCCGGTAAACCTTTAGCCGATATTCACGGCAAACC
AATGATTGTTCGTGTTATGGAGCGGGCGAAACGTTCAGGTGCTGGACGTGTCATTGTGGCAACAGATAATCACGACGTTG
TTGATGCCGTTGTGGCTGCCGGTGGAGAGGCTTGTCTGACCAACGAAAATCACCATTCTGGTACTGAACGATTAGCTGAG
GTTATCAACAAATATCAATTTTCCGATGATGAAATTATCGTTAATGTTCAGGGTGATGAACCACTGATTCCCGAAGAGAT
TATTAAACAGGTTGCAGAGAATTTGGCAGGTTGTAAAGCGGGAATGGCAACGTTGGCCGTGCAGATTCATGATGCAGAGG
AAGCTTTTAACCCTAATGCTGTGAAAGTCGTTATGGATAAACAGGGTTATGCACTCTATTTTTCCAGGGCAACTATTCCT
TGGGAGCGTGGCCGTTTTATTCAATCACGGGAAACGATTGGTGATAATTTTCTGCGTCATATTGGTATTTATGCCTATCG
CGCGGGTTTTATCCGTCGCTACGTGCAATGGGAGCCGAGCCCGTTGGAGCAAATTGAAATGCTGGAACAACTGCGGGTAC
TTTGGTACGGCGAAAAAATTCATGTGGGGATTGCATTAAAGGCACCGGGAGTAGGCGTTGATACGCCGGAAGATTTGGCA
GCAATTAGAAAAGTGTTTACTGAAATCTGA

Protein sequence :
MFTVIIPARFASTRLPGKPLADIHGKPMIVRVMERAKRSGAGRVIVATDNHDVVDAVVAAGGEACLTNENHHSGTERLAE
VINKYQFSDDEIIVNVQGDEPLIPEEIIKQVAENLAGCKAGMATLAVQIHDAEEAFNPNAVKVVMDKQGYALYFSRATIP
WERGRFIQSRETIGDNFLRHIGIYAYRAGFIRRYVQWEPSPLEQIEMLEQLRVLWYGEKIHVGIALKAPGVGVDTPEDLA
AIRKVFTEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 9e-31 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 9e-31 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 7e-31 42