Gene Information

Name : serS (gvip075)
Accession : NP_923662.1
Strain : Gloeobacter violaceus PCC 7421
Genome accession: NC_005125
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 758606 - 759895 bp
Length : 1290 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGCTCGACCCCAAACTGTTGCGCGACGATCCCGCCAAGCTCATCGAACGGCTCAACACCCGCGGCGGCGACTTTACCGA
AGTGATTGAACAACTGGTGGCCCTGGATTCCCAGCGGCGGGCCAGCCAGACCGCATTCAACCGCGCCCAGGCCGAGGGCA
ACCAGATTGGCAAGCAGGTGGGCGAACGGCTGCGCCGGGGTACTGCCGTCGGCGACCCCGAGGTGCTCGCCCTCAAGCAG
CGGGGAATCGATCTCAAAGCCACCCTCGCCCTACTGCAGGATCAAGAGCGCGAGCTTGCCGAGCGCTTCGCGGCACTGTT
GCCGACTTTGCCCAACGTGCCCCGCCCCGAGGTACCGATCGGCAAAGACGAAAACGACAACCGCGAGATGCGCTTCTGGG
GCACCCCCCCTATCTTCGATTTTGAGCCGGCGGCCCACTGGGATCTGGGCGAACGGTTGGGACTGATGAATTTCGCGCGG
GCAACCCTGGTGGCCCAGGCCCGCTTTGTGACCCTGATGGGCGACGGGGCGCTGCTGGAGCGCGCTTTGATCGCTTTTAT
GCTCGATCGCCACCGCGCCCACGGCTATATCGAAATTCTGCCTCCATACCTGGTCAACACCGCTTCGATGACTGGGACCG
GACAGTTGCCCAAATTTGCCGAGGACAGCTTCCGCTGCCGGGACGACGATCTGTGGCTGATTCCAACGGCGGAGGTGCCG
GTCACCAACCTCTACCGAGACGAAATCCTGACAGACATGCAGTTGCCCATTCACCACTGCGCCTTTACCCCCTGCTTCCG
GCGCGAGGCGGGCAGCTACGGCCGCGACACCCGGGGACTTATTCGCCTGCATCAGTTTCACAAAGTCGAACTGGTCAAAT
TCTGCCGCCCGGAGCATTCGCCCACCGAGCACGAAAAACTGGTGGCCGACGCCGAGGATGTGCTGCAGCAACTGGAACTG
CCCTACCGGGTCATCGAGCTGTGTACCGGGGATCTGGGCTTTGGCGCCGCCCGTTGCTTCGATCTGGAGGTGTGGCTACC
CAGCCAGAACCGCTACCGCGAAATTTCCTCCTGCTCGAACTTCGAAGATTTTCAGGCCCGCCGCGCCAATCTGCGCTTCA
AAGCGCCCGACAAAAAAGGCACCGAGTTCGTCCACACCCTCAACGGCTCGGGATTGGCCGTCGGGCGTACCTTCGCCGCC
ATTCTCGAAAATTACCAGAACCGCGACGGCACAGTGCGCGTGCCCGAAGCCCTGAAACCTTACGTGCGCAGGGACGTGCT
CAGCCGGTAA

Protein sequence :
MLDPKLLRDDPAKLIERLNTRGGDFTEVIEQLVALDSQRRASQTAFNRAQAEGNQIGKQVGERLRRGTAVGDPEVLALKQ
RGIDLKATLALLQDQERELAERFAALLPTLPNVPRPEVPIGKDENDNREMRFWGTPPIFDFEPAAHWDLGERLGLMNFAR
ATLVAQARFVTLMGDGALLERALIAFMLDRHRAHGYIEILPPYLVNTASMTGTGQLPKFAEDSFRCRDDDLWLIPTAEVP
VTNLYRDEILTDMQLPIHHCAFTPCFRREAGSYGRDTRGLIRLHQFHKVELVKFCRPEHSPTEHEKLVADAEDVLQQLEL
PYRVIELCTGDLGFGAARCFDLEVWLPSQNRYREISSCSNFEDFQARRANLRFKAPDKKGTEFVHTLNGSGLAVGRTFAA
ILENYQNRDGTVRVPEALKPYVRRDVLSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 9e-102 53