Gene Information

Name : hemC (gvip442)
Accession : NP_926158.1
Strain : Gloeobacter violaceus PCC 7421
Genome accession: NC_005125
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3421125 - 3422111 bp
Length : 987 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
GTGTCCCGCACAGTGATTATCGGTTCGCGCGATTCGCAACTGGCCCTCGTTCAGACCCACTGGGTACGCGACGAACTGCA
GCGCGCCCACCCGGACATCCGGTTTGAAATTGTCGAGATGAAAACCCAGGGCGACAAGATTCTCGATGTCGCCCTCGCCA
AGATTGGCGACAAGGGGCTTTTTACCAAAGAGCTCGAAAGCGCCATGCTCGAGAAGCGCACGGACCTCGCCGTGCACTCG
CTGAAGGATCTGCCCACGGCGCTGCCGCCGGGGCTCATCCTGGGTGCAATCACCGAGCGCGAAGATCCGAGCGATGCGGT
GATCGTGCGCCGGGGACTTGAAGCTGCGGGGCTTGCCGATCTGCCCGAGGGGGCGGTCGTCGGCACTTCTTCTTTGCGCC
GCCTCGCCCAACTCAAGCATCACTACGGCGAACGCCTGCGCTTTCAGGACATCCGGGGCAATCTCAACACGCGCTTGCGC
AAGCTGGATGAGGGCCGCTACGACGCGATTGTGCTCGCCGTGGCAGGCATGCGGCGCTTGGGCTGGTCCGAGCGGATCAG
CGAAGTGCTCTCCCCAGACATCTCGCTGCACGCCGTAGGCCAGGGTGCTCTAGGTATCGAGTGCCGCGAAGCGGACGGGG
AGATCCTGGACTTGCTGACAGTTCTCAACCACCCCCCGACCGCCCGGCGCTGCCGGGCGGAGCGGGCCATGCTGCGCGCC
CTCGAAGGCGGCTGCCAGGTACCGATCGGCGTGTACACCGAACTGGACGACAGCGGTCGGCTCACCCTGCAAGGTATCGT
CGCTTCCCTGGACGGCCGGAATATGGCGCGCGCCTGCCGCAGCGGTCCCGGCGACGCCCCTGAGGCTCTTGGCCGGGCTG
TGGCGGAAGATCTTAAAGCGGCGGGCGCCCAGGCGATCCTTGATCAAATTTTTGTCCTCGTTCGCTCTCCCGGGGTGATC
GCTCCTGGTGCCGCGCCGGCCTCATGA

Protein sequence :
MSRTVIIGSRDSQLALVQTHWVRDELQRAHPDIRFEIVEMKTQGDKILDVALAKIGDKGLFTKELESAMLEKRTDLAVHS
LKDLPTALPPGLILGAITEREDPSDAVIVRRGLEAAGLADLPEGAVVGTSSLRRLAQLKHHYGERLRFQDIRGNLNTRLR
KLDEGRYDAIVLAVAGMRRLGWSERISEVLSPDISLHAVGQGALGIECREADGEILDLLTVLNHPPTARRCRAERAMLRA
LEGGCQVPIGVYTELDDSGRLTLQGIVASLDGRNMARACRSGPGDAPEALGRAVAEDLKAAGAQAILDQIFVLVRSPGVI
APGAAPAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-63 52
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-63 52