Gene Information

Name : guaA (gvip362)
Accession : NP_925561.1
Strain : Gloeobacter violaceus PCC 7421
Genome accession: NC_005125
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2768893 - 2770548 bp
Length : 1656 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCTCCAGCCCGACCGCCGCTGCACGGACCGAAGGGGAAGCCGCCCCCACCGTGCCGACCCAGGTCGAAAGCGGAAC
CGCCCAGCGCCCTGGGCTCGCCCGCGAGATGGTCGCGATCCTCGATTTCGGTTCGCAGTACTCGGAGTTGATCGCCCGCC
GCATCCGCGAGACCAAAGTCTACTCCGAGGTGCTGAGCTACCAGACGCCAATCGCCGAAATCCGGCGCCTGGCCCCCAAG
GGGATCATCCTCTCCGGCGGTCCCAATTCGGTCTACGAGGCCTACGCGCCCCAGTGCGATCCGGCCCTGTGGGAGCTGGG
CATTCCGATCTTGGGCGTCTGCTACGGGATGCAACTGATGGTCCAGCAATTGGGCGGGGCGGTCGAGCGGGCTGAGCGGG
CCGAGTACGGCAAAGCTTCGCTGTTTATCAACGATCCGACGGACCTGTTCACCAACGTCGAAGACGGCACCACCATGTGG
ATGAGCCACGCCGACTCGGTCCTGCGGATGCCCGAGGGTTTTGAGCTGTTGGCCCACACCGAGAACACCCCCTGCGCCGC
CATCGCCCACCACAGCCGCCACCTCTACGGTGTGCAGTTCCACCCGGAGGTGGTCCACTCGCGCGGCGGCATGGCCCTGT
TGCGCAACTTCGTCTACCACATCTGCGGCTGCGAACCCGAGTGGACGACCGCCGCCTTTATCGAGGAGGCGATCCGCGAG
GTGCGCGCCCGGGTGGGCGACAAACGGGTGTTACTCGCCCTTTCCGGCGGGGTCGATTCTTCGACGCTCGCCTTTTTGCT
GCACCGGGCGATCGGCGACAACTTGACGTGTATGTTCATCGACCAGGGCTTCATGCGCAAGAACGAGCCCGAGCGGTTGG
TCAAGCTTTTCAAAGAACAGTTCCACATCCCGGTGGCCTACGTCGATGCGGCCGAGCGCTTTATTGTCCGGCTGGAGGGG
GTGAGCGACCCAGAGCAAAAGCGCAAGATTATCGGCGCCGAATTTATCCGGGTATTCGAGTCGGAGTCCCAGCGGCTCGG
GCCTTTTGACTATCTGGCCCAGGGCACGCTCTATCCCGACATCATCGAGTCGGCGGGCGAAAATATCGACCCGAAGACCG
GCGAGCGGGTGGCCGTCAAGATCAAATCCCACCACAACGTCGGCGGCTTGCCCGAAAATTTGCGCTTCAAGCTGGTCGAA
CCGCTCAAGCGACTCTTCAAAGACGAAGTGCGCCAGGTGGGCCGCGCCCTGGGGCTGCCGGAGGAAATCGTCCAGCGCCA
GCCTTTTCCAGGACCGGGTCTTGCCATCCGTGTGCTGGGAGAACTCACCAAGGACAAAGTCGACATCCTGCGCGAGGCCG
ACTTCATCTTGCGCCAGGAAGTGAACCGCTCCGGCCGCTACAACGACTACTGGCAGTCGTTTGCGGTGCTGCTGCCGGTC
AAGACCGTGGGGGTGATGGGCGACCGGCGCACCTACGCCTACGCCCTCGCCCTGCGCTTTGTGACCAGCGAAGACGGCAT
GACCGCCGACTGGGCGCGGGTTCCCTACGACCTGCTGGAGCAAATCGCCAACCGCATCGTCAACGAGGTGCCGGGCATCA
ACCGGGTGGTGCTGGACATCACCTCCAAGCCGCCCGGCACGATCGAGTGGGAGTAA

Protein sequence :
MTSSPTAAARTEGEAAPTVPTQVESGTAQRPGLAREMVAILDFGSQYSELIARRIRETKVYSEVLSYQTPIAEIRRLAPK
GIILSGGPNSVYEAYAPQCDPALWELGIPILGVCYGMQLMVQQLGGAVERAERAEYGKASLFINDPTDLFTNVEDGTTMW
MSHADSVLRMPEGFELLAHTENTPCAAIAHHSRHLYGVQFHPEVVHSRGGMALLRNFVYHICGCEPEWTTAAFIEEAIRE
VRARVGDKRVLLALSGGVDSSTLAFLLHRAIGDNLTCMFIDQGFMRKNEPERLVKLFKEQFHIPVAYVDAAERFIVRLEG
VSDPEQKRKIIGAEFIRVFESESQRLGPFDYLAQGTLYPDIIESAGENIDPKTGERVAVKIKSHHNVGGLPENLRFKLVE
PLKRLFKDEVRQVGRALGLPEEIVQRQPFPGPGLAIRVLGELTKDKVDILREADFILRQEVNRSGRYNDYWQSFAVLLPV
KTVGVMGDRRTYAYALALRFVTSEDGMTADWARVPYDLLEQIANRIVNEVPGINRVVLDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-141 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-141 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-141 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-127 50