Gene Information

Name : SERS (WS0872)
Accession : NP_907081.1
Strain : Wolinella succinogenes DSM 1740
Genome accession: NC_005090
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 827818 - 829104 bp
Length : 1287 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATTTGAAGCTTTTGATGAATGATTTTGAAGAGGTGGCAGAGAGGCTGGCCAAGCGCCATTTGGAGGCTGATTT
TTTGGAGCAGGCGCGCCTTTTGGCGGGTCAATACAAGGCGAAAAAGCGCGAGAGCGAAGAGTTGCAAGCCGAGCAAAACG
CCAAGTCTAAACTCTTTGGCCAATACAAAAAAGAGGGAAAAGAGATCGACTCCCTCAAAGCAGAGCTAGACACCCTCAAG
ATTCGTTTGAGTGAGATTCTCCCTGAGGTGAGTGTTTTAGAGAGAGAGCTAGAATCGCTTGCACTCATTATTCCCAACCT
GCCTGATGAGAAGACCCCCATAGGAAGAGATGAGCATGACAATATTGAAATTAGGCGCGTGCTAGAGCCTAAGATGTTCG
ACTTCCGCCCCAAAGAGCATTGGGAGTTGGCCGAGCAGAATGGTTGGATTGAGTTTGATCGTGGCGTGAAGCTGGCCAAG
AGCCGATTTTCGGTGTTGCGCAAAGAGGGAGCGAGAATGAGCCGAGCGCTCATTAGCTATATGCTTGATTTTAATCACTC
TAGAGGCTTTGAAGAGGTGGTTACGCCCGTGATCGTTAATAGAGAAACGCTCCTTGGAACGGGGCAGTTGCCTAAGTTTG
AAAATGATCTTTTTAAAATCTCTGAAGTGATTGAAGAGGAGCAGGGGGGCGAGAAGGGAAGGGGGCATGAACTCTATTTG
ATTCCCACGGCCGAAGTGACACTCACCAATCTCTATCGAGATGAGATTATTCCCCACGATGAACTTCCCCTCCTGCTCAC
GGCGCACACGCCATGTTTTCGCAAAGAGGCAGGAAGCGCAGGGCGTGACACAAGAGGGATTATTCGCCAGCATCAGTTTG
ACAAAGTGGAGCTAGTGGCACTCACAAAGCCCGAAGAGAGTGATGCGATTCAGCAAAAGATGATCGATTGCGCCTCTGAC
CTTTTGAGCTCTCTAGGATTGCCTCATCGCTTAGTCCAGCTCTGCGGAGGGGATCTTGGGTTTGGAGCGAGCAACACGGT
GGATATTGAGGTTTGGCTTCCGGGGCAAAACTGCTATCGTGAGATCAGCTCCATCTCCAATACAAGAGATTTTCAAGCTA
GACGCGCCATGATTCGCTATAAAGACGAGGATAAAAAAAATCGACTCGTCCACACTCTCAATGGATCCTCTTTGGCGGTA
GGCAGAACACTGGTAGCCATCATGGAAAACTACCAAAACGCCGATGGAACCATCGAGATTCCTGAGGTTTTACGCCGCTA
CCTATGA

Protein sequence :
MIDLKLLMNDFEEVAERLAKRHLEADFLEQARLLAGQYKAKKRESEELQAEQNAKSKLFGQYKKEGKEIDSLKAELDTLK
IRLSEILPEVSVLERELESLALIIPNLPDEKTPIGRDEHDNIEIRRVLEPKMFDFRPKEHWELAEQNGWIEFDRGVKLAK
SRFSVLRKEGARMSRALISYMLDFNHSRGFEEVVTPVIVNRETLLGTGQLPKFENDLFKISEVIEEEQGGEKGRGHELYL
IPTAEVTLTNLYRDEIIPHDELPLLLTAHTPCFRKEAGSAGRDTRGIIRQHQFDKVELVALTKPEESDAIQQKMIDCASD
LLSSLGLPHRLVQLCGGDLGFGASNTVDIEVWLPGQNCYREISSISNTRDFQARRAMIRYKDEDKKNRLVHTLNGSSLAV
GRTLVAIMENYQNADGTIEIPEVLRRYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-86 48