Gene Information

Name : lysS (WS0084)
Accession : NP_906352.1
Strain : Wolinella succinogenes DSM 1740
Genome accession: NC_005090
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 81955 - 83478 bp
Length : 1524 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGTTTTTTTCTAATCAGTATATCAAGCAGAGAATCCAAAAAGGGGAGGAGCTAAGGGAGCTTGGACGCAACCCCTATGA
TAATCAACTCATGCGCACTCTCACCCATGCGCAATTTTTGCAAAAGTTTGAGGCGCTTAAGAGCTTAGAGAGTGAAGAGA
AGCGCGATGAAAGCGCCAAAGAGAGCATCGCGGGTCGGATTAAATTTCTTCGTCATATGGGAAAGGCGGCCTTTGCTAAA
ATTGAGGATGAGAGCGGAATCCTTCAGATTTACTTCTCCCAAAATGAGCTTGGCGAAGATTTTAAGATGCTCAAAAAGCT
GGCCGAGGTGGGTGATATTGTGGCGGTGAGTGGCTTTCCTTTTGTCACCAAAACGGGCGAATTGAGCCTCCATGCGTTGG
AGATGAAGATTCTCACCAAAGCCATCGTTCCTCTGCCTGAGAAGTATCATGGGCTCGTGGATGTAGAGCTTCGCTATCGT
CAGCGCTATCTTGACCTCATTATGAACCCTGAGGTCAAAGAGACCTTCAAGCTCCGCAGTCAAGTCGTCTCTAGTGTGCG
AAGATTCTTTGAGGAGAGGGGATTCTTGGAGGTGGAGACTCCCATGATGCACCCCATTCCTGGTGGCGCCAATGCCAAGC
CCTTCATCACGCACCACAACGCCCTAGGGGTTGATAGGTATCTAAGAATCGCTCCAGAGCTCTACCTTAAACGCCTTGTC
GTGGGGGGGTTTGAGGCGGTTTTTGAGATCAATCGAAACTTCCGTAATGAGGGGATGGATCACTCTCATAACCCTGAATT
CACTATGATTGAATTCTATTGGGCCTACAAAACCTATCACGAGTTGATGAGCCTCACCGAGGAGCTTTTTGGCTACCTCT
TTGAGCGCTTGGGCTTGCCCAAGATTCTTCCCCATGGTGAGGAGATGATCGACTTCTCCCTTCCCTTTAGGAGGATTCCC
TACAAGAAAGCGCTTCATGAGATCGGAGGGGTGCCTTTGGAGGTGATCGAGGAGAAGGAGAAGCTTCGAGCCTATTTGAT
CGAAAAAGGGGTGAGGCTAGAGGGCGAGATGGGAATTGGAAAGCTTCAGGCGGAGGCGTTTGATGCCTTTGTTGAGGAGA
AGCTTATCAACCCCACTTTCATCACTGAATTCCCCATCGAGATCAGTCCACTAGCTAGAAGAAGTGATGAGAATCCCCAA
ATTGCTGATCGTTTTGAGCTTTTCATCGGCAAAAAAGAGATCAGTAATGGCTTTAGCGAGCTTAATGATCCCCTTGATCA
GCTTGAGCGTTTCAAGGCGCAGGTGGCGGCCAAGAATGCGGGTGATGAAGAGGCTCAACATATGGATGAAGACTATGTTT
GGGCTCTAGGACATGGACTGCCTCCCACGGCGGGAGAGGGGATCGGGATCGATCGCCTTGTGATGTTGCTCACCAATAAC
CGCTCCATTAAGGATGTAATCCTATTCCCTGCGCTCAAAGTTCAAAAGAGCGACTACACCATTTTGAAGGAAGAAGAAGC
ATGA

Protein sequence :
MFFSNQYIKQRIQKGEELRELGRNPYDNQLMRTLTHAQFLQKFEALKSLESEEKRDESAKESIAGRIKFLRHMGKAAFAK
IEDESGILQIYFSQNELGEDFKMLKKLAEVGDIVAVSGFPFVTKTGELSLHALEMKILTKAIVPLPEKYHGLVDVELRYR
QRYLDLIMNPEVKETFKLRSQVVSSVRRFFEERGFLEVETPMMHPIPGGANAKPFITHHNALGVDRYLRIAPELYLKRLV
VGGFEAVFEINRNFRNEGMDHSHNPEFTMIEFYWAYKTYHELMSLTEELFGYLFERLGLPKILPHGEEMIDFSLPFRRIP
YKKALHEIGGVPLEVIEEKEKLRAYLIEKGVRLEGEMGIGKLQAEAFDAFVEEKLINPTFITEFPIEISPLARRSDENPQ
IADRFELFIGKKEISNGFSELNDPLDQLERFKAQVAAKNAGDEEAQHMDEDYVWALGHGLPPTAGEGIGIDRLVMLLTNN
RSIKDVILFPALKVQKSDYTILKEEEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-111 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS NP_906352.1 lysyl-tRNA synthetase VFG1668 Protein 7e-112 51