Gene Information

Name : fliI (WS2207)
Accession : NP_908297.1
Strain : Wolinella succinogenes DSM 1740
Genome accession: NC_005090
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 2089516 - 2090820 bp
Length : 1305 bp
Strand : -
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGCCCTTGTATGCCCTTCGTGAGAAATTGGGGAAAAAGTCCCTCTCTCCCACCTTTGGAACAGTTGTCAAAGTCTCTTC
GGGGGCGATTGTGGTGGTGGGGCTCAGGCCCTCAGTGGGAGACATTGTGCGAATCATTCAGGGCGAGAATCACCACGAAA
GCATGGGCATGGTGACGGTGGTGGAATCAGAGAGCTTCACCGTCTCGCCTTTCTCCTTTATCGAGGGGAGCAAGGTGGGT
GATCGAGTCTATCTGAATAATAGAGGTCTTCAGATTCCTGTGGGAGCGGGACTTCTTGGAAGGGTGGTTGATCCATTGGG
ACGACCTATTGATGGGGCGGGGGAGATTCTTGGCACGGAATATGCCCCCATCATCAAACCTCCCATTGCCGCGATGAAGC
GAGGAATGATCGATGAGGTCTTTAGCGTGGGGGTGAAGAGCATCGATGGGCTCCTCACTTGCGGTAAAGGTCAAAAATTG
GGAATCTTCGCGGGAAGCGGCGTGGGGAAGAGCACACTTATGGGGATGATCGTCAAAGGAGCGAGTGCACCCATCAAGGT
GATTGCCCTCATTGGAGAGCGTGGGCGAGAGGTGCCCGAGTTCATTGAAAAGAATCTAGGGGGGAATCTAGAAAACACGG
TTTTGGTGGTGGCCACTAGTGACGATTCTCCTCTTATGCGTAAATATGGAGCTTTTAGTGCGATGAGCGTGGCGGAGTAT
TTCAAAGCACGCGGAGAGGATGTGCTCTTTATGATGGATTCGGTCACTCGATTCGCCATGGCGCAACGCGAGATCGGTCT
AGCTCTAGGCGAGCCCCCCACGAGCAAGGGCTATCCTCCCTCTGTCCTCACGCTTTTGCCTCAGCTCATGGAGCGCGCGG
GCAAAGAGGAGGGGCATGGTTCGATCACTGCTTTTTTCACCGTGCTGGTGGAGGGGGATGACATGGGCGATCCTATCGCT
GATCAGAGTCGAAGCATCCTAGATGGACATATTGTCCTCTCTAGGGAGCTGACTGATTTTGGAATCTATCCTCCCATCAA
TATCCTCAACTCCGCCTCCAGGCTCATGAATGACGTGAGCACCAAAGATCATGTGCTAGCCGCTCGCAAGTTTCGACGCC
TCTATTCGCTCCTCAAGGAGAATGAGGTTTTGATTCGAATCGGCGCCTATCAAAAGGGCAATGATAGAGAGTTGGATGAG
GCGATTGAGAAAAAAGAGAGGATGGAGGGTTATCTAAAGCAGAACTTCGATGAGAATTGGGAGTTTGAAAAGAGCGTCAG
TGAGCTGGTGACGCTCATGGGATAG

Protein sequence :
MPLYALREKLGKKSLSPTFGTVVKVSSGAIVVVGLRPSVGDIVRIIQGENHHESMGMVTVVESESFTVSPFSFIEGSKVG
DRVYLNNRGLQIPVGAGLLGRVVDPLGRPIDGAGEILGTEYAPIIKPPIAAMKRGMIDEVFSVGVKSIDGLLTCGKGQKL
GIFAGSGVGKSTLMGMIVKGASAPIKVIALIGERGREVPEFIEKNLGGNLENTVLVVATSDDSPLMRKYGAFSAMSVAEY
FKARGEDVLFMMDSVTRFAMAQREIGLALGEPPTSKGYPPSVLTLLPQLMERAGKEEGHGSITAFFTVLVEGDDMGDPIA
DQSRSILDGHIVLSRELTDFGIYPPINILNSASRLMNDVSTKDHVLAARKFRRLYSLLKENEVLIRIGAYQKGNDRELDE
AIEKKERMEGYLKQNFDENWEFEKSVSELVTLMG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-77 51
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-78 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-79 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-78 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-79 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-79 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-79 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-77 50
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-77 49
escN AAC31513.1 L0034 Virulence LEE Protein 4e-77 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-77 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-77 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-77 49
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-76 48
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-76 48
escN AAK26715.1 EscN Virulence LEE Protein 4e-76 48
escN AAL57542.1 EscN Virulence LEE Protein 4e-76 48
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-76 48
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-77 48
escN YP_003236088.1 translocator EscN Virulence LEE Protein 7e-77 48
escN AAC38383.1 EscN Virulence LEE Protein 1e-76 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-77 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-77 48
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-73 48
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-73 47
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-73 47
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-68 47
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-68 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-68 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-68 47
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 7e-68 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 7e-58 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 6e-62 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-60 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-62 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-62 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 8e-61 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-66 44
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-61 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-60 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-60 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-65 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 7e-59 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 5e-58 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 5e-58 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-58 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-58 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-58 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 4e-58 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI NP_908297.1 flagellum-specific ATP synthase VFG0390 Protein 2e-81 53
fliI NP_908297.1 flagellum-specific ATP synthase VFG0048 Protein 1e-83 52
fliI NP_908297.1 flagellum-specific ATP synthase VFG0192 Protein 3e-82 52
fliI NP_908297.1 flagellum-specific ATP synthase VFG2144 Protein 1e-79 50
fliI NP_908297.1 flagellum-specific ATP synthase VFG1254 Protein 6e-77 50
fliI NP_908297.1 flagellum-specific ATP synthase VFG2331 Protein 1e-75 49
fliI NP_908297.1 flagellum-specific ATP synthase VFG0812 Protein 2e-77 49
fliI NP_908297.1 flagellum-specific ATP synthase VFG0730 Protein 7e-77 48
fliI NP_908297.1 flagellum-specific ATP synthase VFG0515 Protein 4e-68 47
fliI NP_908297.1 flagellum-specific ATP synthase VFG1008 Protein 6e-63 44
fliI NP_908297.1 flagellum-specific ATP synthase VFG0555 Protein 2e-58 42
fliI NP_908297.1 flagellum-specific ATP synthase VFG2459 Protein 1e-63 42