Gene Information

Name : thiC (WS1941)
Accession : NP_908047.1
Strain : Wolinella succinogenes DSM 1740
Genome accession: NC_005090
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1836897 - 1838246 bp
Length : 1350 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGCGCCAAAGCTGGATAGAGAAGCGAAAAAACGACTCGGTGAGGACTCAGCTCCACTACGCTAGAGCGGGAATCATCAC
CGAAGAGATGCAAGCCGTTGCCAATGTCGAAGGGTTAAGCGAAGAGCTTATCCGTAGCGAAGTGGCTAGGGGTCGCCTTG
TCATTCCCGCCAACATCCATCACCTCTCCCTCTCCCCTATGGGAATCGGAGTCGCGGCGAGAACCAAAATCAATGCCAAC
ATCGGCAGCTCCTCTTTAGCGAGCTGTATCGAAGAGGAGATCGAAAAGACGCTCGTCTCCATTAAATATGGAGCGGACAC
CATCATGGACCTAAGCACAGGAGGCGATTTAGACGCGATTCGATGCGCGGTGATCGAGCACTCCAGCGTCCCTATTGGAA
CGGTGCCCATCTATCAGATTCTTCATGATGTTCAGGGCGATATCAAAAACCTCACCATCGATTCGATGCTGGAGGTGATG
GAGCGCCAAGCACGCCAAGGGGTGAGCTACTTCACGATTCACTGTGGATTCCTCCTAGAGCACCTTCCCAAAGTCGCCAA
GCGCAAAATGGGAATCGTGAGTCGTGGCGGCAGTCTCATGGCCTCCTACATGATGCACTATCACAAGCAAAATCCTTTTT
ATGAGGCGTTTGATGAGATATTAGCCATCTGCAGGGAGTATGATGTGACGCTCAGCCTTGGAGATTCGCTTCGCCCGGGC
TGCCTAGCCGATGCCAGCGATGAGGCTCAGCTAGCTGAGCTCAAAGTCTTGGGCGAGCTCACTTTGAGGGCCTGGGAGAA
GGATGTGCAGGTGATGATTGAAGGACCCGGCCATGTTCCCATGAATCAGATCGAGCGCAATGTGAAGCTTCAAAAAGAGC
TCTGCCATGAGGCGCCTTTTTATGTGCTTGGCCCGCTAGTGACGGATATCGCCGCAGGGTATGACCATATCGCCTCCGCC
ATTGGTGCAGCCATTGCTGCATGGAAAGGGGTCGCGATGCTCTGCTATGTCACCCCCAAGGAGCACCTAGGACTCCCCAA
TGCCAAAGATGTTCGCGAGGGAATCCTTGCCTACAAGATCGCTGCCCACGCGGCGGATATTGCTAGGGGGAGAATCGGGG
CGAGGGATAGAGACGATGCGATGAGCGATGCGCGCTACGCCTTTGACTGGAATCGCCAATTCGAGCTCGCCCTAGACCCC
GATCGCGCGAAAGAGTATCATGATGAATCACTTCCTCAAGAGGTTTTCAAGGAGGCAAAATTTTGCTCCATGTGCGGGCC
AAAGTTTTGCAGTTATAAAATCAGTCAAGAGATTGTCTCAAAACATGCATCAGGAGAATCACTCACATGA

Protein sequence :
MRQSWIEKRKNDSVRTQLHYARAGIITEEMQAVANVEGLSEELIRSEVARGRLVIPANIHHLSLSPMGIGVAARTKINAN
IGSSSLASCIEEEIEKTLVSIKYGADTIMDLSTGGDLDAIRCAVIEHSSVPIGTVPIYQILHDVQGDIKNLTIDSMLEVM
ERQARQGVSYFTIHCGFLLEHLPKVAKRKMGIVSRGGSLMASYMMHYHKQNPFYEAFDEILAICREYDVTLSLGDSLRPG
CLADASDEAQLAELKVLGELTLRAWEKDVQVMIEGPGHVPMNQIERNVKLQKELCHEAPFYVLGPLVTDIAAGYDHIASA
IGAAIAAWKGVAMLCYVTPKEHLGLPNAKDVREGILAYKIAAHAADIARGRIGARDRDDAMSDARYAFDWNRQFELALDP
DRAKEYHDESLPQEVFKEAKFCSMCGPKFCSYKISQEIVSKHASGESLT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-101 57
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-101 57
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 4e-97 54