Gene Information

Name : hemC (WS1578)
Accession : NP_907718.1
Strain : Wolinella succinogenes DSM 1740
Genome accession: NC_005090
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1498035 - 1498970 bp
Length : 936 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAATAAAATCATCATTGGAACCCGAGGAAGCGTCTTGGCGCTTTGGCAGGCGGAGTATGTAAAAGCGGAGCTAGAGAG
GGCTCATGAGGGGCTTAGCGTGGAGCTAAAAATCGTCAAAACCAAGGGCGATAAAATCCTAGATGTGCCTTTAGCTAAGG
TCGGTGGCAAAGGGCTTTTCACCAAAGAGCTGGAGGAGATGATGCTTCAAGGCGAAATTGACCTTGCCGTGCACTCTCTT
AAGGATGTTCCCGTGGAGCTTATCGAAGGCCTCACTCTCTCAGCGATCACGGAGCGAGAGGATGTGAGAGACTGCTTTTT
AAGCGATAAATACGCTTCGCTAGAGACACTTCCTTTGGGAGCCAAGGTGGGCACCACTTCTCTTAGGCGCTCTATGCAGA
TCAAGTCGATGCGAAGTGACCTGGACACCGAGAGCTTGAGGGGAAATGTTCAGACGCGAATCAAGCGCCTCAAAGAGGGA
GATTTTGATGCCATTATCCTTGCTACGGCGGGAGTGAATCGGCTCGATCTTTGGAAAGAGGTCAATTATGTGATTCCTAT
TGACACGGAGATGATGATTCCCGCGATGGGGCAGGCGGCTTTGGGAATTGAGTGCAAAGAGGGGAGTGAGGCCTTTAGGC
TCACGCAGATTCTCGAGGATAAGAAAGCAAGAATCGAAACCACGGCCGAGAGAGAGTTTGTGCGTGTGCTAGAGGGGGGT
TGTCAAGTGCCAATCGGGGCGAATGCCTATTTGGAAGGAGAGACCCTTCATCTAAAAGTAGCGGTGGGGCTCCCTGATGG
GAGTGAGATCCTCATGGATCGTCTAAGTGCCCCCAAGGGTGAGGCAGTGCGCCTAGGGAGAGAGCTTGCCGCGCGCCTTA
TAGCTAAGGGAGCGCGTGAATTGTTGAGACGCGCCGAGGAGATGGCCTTTCAATAA

Protein sequence :
MNKIIIGTRGSVLALWQAEYVKAELERAHEGLSVELKIVKTKGDKILDVPLAKVGGKGLFTKELEEMMLQGEIDLAVHSL
KDVPVELIEGLTLSAITEREDVRDCFLSDKYASLETLPLGAKVGTTSLRRSMQIKSMRSDLDTESLRGNVQTRIKRLKEG
DFDAIILATAGVNRLDLWKEVNYVIPIDTEMMIPAMGQAALGIECKEGSEAFRLTQILEDKKARIETTAEREFVRVLEGG
CQVPIGANAYLEGETLHLKVAVGLPDGSEILMDRLSAPKGEAVRLGRELAARLIAKGARELLRRAEEMAFQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-62 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-62 50