Gene Information

Name : leuS (CV_0505)
Accession : NP_900175.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 530163 - 532781 bp
Length : 2619 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAACAATACAGCCCGCGCGCGGTGGAAGCCGCCGCCCAACAGAAATGGCAGAAGACTGCCGCCTTCAAGGCCGT
GGAGGACGCGTCGCGTCCCAAGTACTACGCGCTGTCGATGTTCCCGTACCCGTCCGGCAAGCTGCACATGGGCCACGTGC
GCAACTACACCATCACCGACGTGCTGGCCCGCTTCAAGCGCCTGCAGGGCTTCAACGTGCTGCAGCCGATGGGCTGGGAC
GCCTTCGGCCTGCCGGCCGAGAACGCGGCGATGAAGAACGGCGGCGCGCCGGCGGCGTGGACCTACGCCAACATCGAATA
CATGAAAACCCAGCTGGACAGCCTGGGCTTCGCCCTGGACTGGGAGCGCGAGCTGGCCACCTGCAAGCCGGACTACTACC
GCTGGGAGCAGTGGCTGTTCACCCGCCTGTTCGAGAAGGGCGTGATCTACAAGAAGAACGGCGTGGTCAACTGGGACCCG
GTGGACCAGACCGTGCTGGCCAACGAGCAGGTGGTGGACGGCCGCGGCTGGCGCTCCGGCGCGCTGGTGGAAAAGCGCGA
AATCCCGATGTACTACTTCCGCATCACCGACTACGCCGAGCAGCTGCTGGCGGACCTGGACAAGCTTGACGGCTGGCCGG
AGCAGGTCAAGACCATGCAGCGCAACTGGATTGGCAAGAGCTACGGCTCCGACGTGGTGTTCCCGTACGACGAGGCCAGC
ATCGGCCACGCCGGCGAACTGAAGGTTTACACCACCCGTCCGGACACGCTGATGGGCGCCACCTACGTCGCCGTCGCCGC
CGAGCACCCGCTGGCCACCCAGGCCGCGGCCGGCAATGCCGCGCTGCAGGCCTTCATCGCCGAGTGCAAGTCCGGCTCCG
TCGCCGAGGCCGACGTGGCCAAGATGGAAAAGAAGGGCATGGACACCGGCCTGTCCGTGATCCACCCGCTGACCGGCGAA
CGCTTGCCGGTATGGGTGGCCAACTACGTGCTGTGGGGCTACGGCGAAGGCGCGGTGATGGCGGTGCCGGCGCACGACGA
GCGCGATTTCGAGTTCGCCAACAAGTACCAGCTGCCGATCAAGCAGGTGATCGCGCTGGCGTCCGGCGACGGCGAGTACG
ACGCCGCCAACTGGCAGGAATGGTACGGCGCCAAGGATGACACCGTGAAGACGGTCAATTCCGGCAAGTACGACGGCCTG
GGCTATCAAGCCGCTTTCGACGCCATCATCGGCGACCTGCAGGCCAAGAGCCTGGGCCAGAAAAAGACCCAGTACCGGCT
GCGCGACTGGGGCATCTCCCGCCAGCGCTACTGGGGCTGCCCGATCCCCATCATCCATTGCCCGAGTTGCGGCGACGTGC
CGGTGCCGGAAAAAGACCTGCCGGTGACGCTGCCGGAAAACGTGATTCCGGACGGCGCCGGCTCGCCGCTGGCCAAGATG
CCGGAATTCTACGAAACCAGCTGCCCGAAGTGCGGCGGCGCGGCCAAGCGCGAAACCGACACCATGGACACCTTCGTGGA
GTCCAGCTGGTACTACGCCCGTTACGCCTCGCCGAAGTGCGACACCGCGATGGTGGACAAGCAGGCCGCCGATTACTGGC
TGCAGGTCGACCAATACGTGGGCGGCATCGAACACGCGATCCTGCACCTGCTGTATGCGCGCTTCTTCCACAAGCTGATG
CGCGACGAAGGCCTGGTGTCGTCGGACGAGCCGTTCAAGAGCCTGCTGACCCAGGGCATGGTGGTGTGCGAGACCTTCTA
CCGCGACCTGCCCAACGGCACCAAGGACTGGATCGCGCCGCAGGACGTCATCCTGGAACGCGATGCCAAGGGCAAGATCG
TCGCCGCCAAGCACCGCGTCGACGGCCAGCCGGTGGTGGTGGGCGGCATCGAGAAGATGTCCAAGTCCAAGAACAACGGC
GTGGATCCGCAGGAGTTCATCGAGAAATACGGCGCCGACACCGCGCGCCTGTTCATGATGTTCGCCGCGCCGCCGGAGCA
GAGCCTGGAATGGTCCGACGCCGGCGTGGAAGGCGCGTTCCGTTTCCTGAAGCGTTTGTGGAAAACCGCGCGCGAGCACG
TCGAGGCCGGCGTGGTGGCGCCGTACGCTTCCGGCGAGTTGAACGCCAGCCAGAAGGAGCTGCGCTTCAAGCTGCACGGC
ACCATCCAGAAAGTGGCCGACGACTACGGCCGCCGCCAGCAATTCAATACCGCCATCGCCGCGGTGATGGAGCTCTTGAA
CGCCTACGACAAGGCCGACACTTCGGGCGACATCGGCCGCGCGGTGGCGCAGGAAGTGCTGGAAGCCGCCACCCTGCTGC
TGTCGCCCATCGTGCCGCACGTCTGCGACGGCATCTGGAACGCGCTGAAGCCGGGCACCGAGCTGCTGGCGCAAGCCTGG
CCCAAGGTGGACGAGGCCGCGCTGGTGAAGAGCGAGATCGAGCTGATGGTGCAGGTGTGCGGCAAGCTGCGCGGCAGCGT
GACCGTGGCCGCCGATGCCGCCAAGGACGCGATCGAAGCCGCCGCGCTGGCGCACGAGAACGTGATCAAGTTCATGGAAG
GCAAGCCGGCCAAGAAGATCATCGTGGTGCCGGGCCGCCTGGTGAACATCGTCGTCTAA

Protein sequence :
MQEQYSPRAVEAAAQQKWQKTAAFKAVEDASRPKYYALSMFPYPSGKLHMGHVRNYTITDVLARFKRLQGFNVLQPMGWD
AFGLPAENAAMKNGGAPAAWTYANIEYMKTQLDSLGFALDWERELATCKPDYYRWEQWLFTRLFEKGVIYKKNGVVNWDP
VDQTVLANEQVVDGRGWRSGALVEKREIPMYYFRITDYAEQLLADLDKLDGWPEQVKTMQRNWIGKSYGSDVVFPYDEAS
IGHAGELKVYTTRPDTLMGATYVAVAAEHPLATQAAAGNAALQAFIAECKSGSVAEADVAKMEKKGMDTGLSVIHPLTGE
RLPVWVANYVLWGYGEGAVMAVPAHDERDFEFANKYQLPIKQVIALASGDGEYDAANWQEWYGAKDDTVKTVNSGKYDGL
GYQAAFDAIIGDLQAKSLGQKKTQYRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEKDLPVTLPENVIPDGAGSPLAKM
PEFYETSCPKCGGAAKRETDTMDTFVESSWYYARYASPKCDTAMVDKQAADYWLQVDQYVGGIEHAILHLLYARFFHKLM
RDEGLVSSDEPFKSLLTQGMVVCETFYRDLPNGTKDWIAPQDVILERDAKGKIVAAKHRVDGQPVVVGGIEKMSKSKNNG
VDPQEFIEKYGADTARLFMMFAAPPEQSLEWSDAGVEGAFRFLKRLWKTAREHVEAGVVAPYASGELNASQKELRFKLHG
TIQKVADDYGRRQQFNTAIAAVMELLNAYDKADTSGDIGRAVAQEVLEAATLLLSPIVPHVCDGIWNALKPGTELLAQAW
PKVDEAALVKSEIELMVQVCGKLRGSVTVAADAAKDAIEAAALAHENVIKFMEGKPAKKIIVVPGRLVNIVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-139 41