Gene Information

Name : murD (CV_4345)
Accession : NP_904015.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 4684909 - 4686270 bp
Length : 1362 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGATTACGCCAATCGACATGTGACGGTGGTGGGATTGGGGGGCTCGGGCCTGGCGGCCGCGCGCTACCTGGCCGCCCA
CGGCGCGCGCGTGCGCGTGGCCGACGCCAATCCGTCCGCCGAGCGGCTGGCCGAGCTGGAACGCTGCCTGCCGGGCGTGG
AAGTGATGGTCGGCGCGTTCGACGACGCCACCTTCGCCGGCGCCGAGCTGCTGGTGGTCAGTCCCGGCGTGCCGCTGGCC
AACCCGGCCATCGCCGCCTTCCGCCGCGCCGGCGGCGAGGTGGTCGGCGACATCGAGATCCTGGCGCGCGCGATCCAGGG
CGACGGCAGCAAGGTGATCGCGATCACCGGCTCCAACGGCAAGAGCACGGTCACCAGTCTGGTCGGCCACTTGTGCGAGG
CGGCCGGGCTGGATACCGTCGTCGCCGGCAATATCGGCCTGGCGGTGCTGGAGGCTTTGCTCGCGCGCGAACAGAGCGGC
AAGCGCCCCGACGTGTGGGTGCTGGAGCTGTCCAGCTTCCAGCTGGAGTCCACTTTCTCGCTGGCGGCCGACGCCGCCAC
CGTGCTGAACATTTCCGAGGATCACCTCGACCGTTACGCCGACCTGCTGGACTACGCGCATGCCAAGACCCGGGTGTTCA
ACGGCAAGGGCGTCCAGGTGCTGAACAAGGACGACGCGCTGGTGCGGGCGATGGTCCGCCCCGGCCATCCGGTCAAGTGG
TTCTCGCTGAACGGCGCGGCAGACTACGCGCTGGCGCGCAACGGCGGCTACTGGCTGAAAGTGGACGGCGAAAAGGTGTT
CGACTGCGCCGACATGCAGCTGCAGGGCCTGCACAACGCCGCCAACGCGCTGGCCGCGTTGGGCCTGTGCCAAGGCATAG
GCCTGCCGCTGGAGAAGCTGCTGGACGGGCTGAAGACCTTCCGCGGCCTCGCGCATCGCGTCGAGCTGGTAGACGAATTC
GACGGTATTGCGTTTATCGATGATTCCAAGGGCACCAACGTCGGCGCGACCGAGGCCGCGCTGAACGGCATGACCCGCCA
GGTGGTGCTGATCGCCGGCGGCGACGGCAAGGGCCAGGACTTCGCGCCGCTGAAGCCGGCCTGCCAGCGCATCGCCCGCG
CGGTGCTGCTGATCGGCCGCGACGCCGGCCGGATCGAGGCCGCGCTGGAAGACAGCGGCCTGGCGCTGGAGCGCTGCGAC
ACGCTGGAGGAGGCTACCCGCCGCGCGGCGGCGCTGGCCCGTCCGGGCGACGTGGTGCTGCTGTCGCCGGCCTGCGCCAG
CCTGGACATGTTCAAGAATTACGCGCACCGGGCGCAGGTGTTCATCGACACCGTGGCGGCGGTGAAGGCGGCGCGGGCAT
GA

Protein sequence :
MDYANRHVTVVGLGGSGLAAARYLAAHGARVRVADANPSAERLAELERCLPGVEVMVGAFDDATFAGAELLVVSPGVPLA
NPAIAAFRRAGGEVVGDIEILARAIQGDGSKVIAITGSNGKSTVTSLVGHLCEAAGLDTVVAGNIGLAVLEALLAREQSG
KRPDVWVLELSSFQLESTFSLAADAATVLNISEDHLDRYADLLDYAHAKTRVFNGKGVQVLNKDDALVRAMVRPGHPVKW
FSLNGAADYALARNGGYWLKVDGEKVFDCADMQLQGLHNAANALAALGLCQGIGLPLEKLLDGLKTFRGLAHRVELVDEF
DGIAFIDDSKGTNVGATEAALNGMTRQVVLIAGGDGKGQDFAPLKPACQRIARAVLLIGRDAGRIEAALEDSGLALERCD
TLEEATRRAAALARPGDVVLLSPACASLDMFKNYAHRAQVFIDTVAAVKAARA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 2e-60 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 2e-60 43