Gene Information

Name : metB (CV_4049)
Accession : NP_903719.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4380032 - 4381177 bp
Length : 1146 bp
Strand : -
Note : identified by sequence similarity; ORF located using Glimmer/GeneMark/Blastx/COG0626

DNA sequence :
GTGAAATTCGCTACCCGCGCCATCCATGTCGGCTACGACAATGCCGAACACAACCGCTCGGTGATGCCGCCGCTGTACCA
GACCTCGGCCTTCGCCTTCGACCATGTCGGCGAGGATTTGCGCTACGCCTACGCCCGCACCGGCAATCCGACCCGCAGCG
CGCTGCAGGACTGCCTGGCCAGCCTGGAAGAGGCCAGGCACGGCCTGGCCTTCTCCAGCGGCATGGCGGCGATAGACGCG
GTGCTGCGCGCCTGCCTGAAGCCGGGCGACGAGGTGATCGCGGTGGCGGATCTGTACGGCGGCGCTTACCGGCTGCTGAC
CCGGGTGATGCAGCCGGCCGGTATCAAGGTGAGCTTCGTGGACCTGTCCGACCCGGCGCGGCTGGAGGCGGCGATCACGC
CGGCCACCCGGCTGCTGTGGCTGGAGTCGCCGACCAATCCGCTGCTGGGCATGGTCGATATCGCCGCGCTGTCCGCGATC
GCCCATCGCCACAATGTAAAAGTGGCGGTGGACAATACCTTCGCCACGCCGTATCTGCAGCAGCCGCTGCTGCTCGGCGC
CGACATCGTCGTGCACTCGGCCACCAAGTACCTGGGCGGGCACTCCGACGTGCTGCTGGGCCTGGTGGCGGTCAGCGACG
ACAAGCTGCACCACGATATCCGCTTCCTGCAGAACGCCGCCGGCGCGGTGCCCGGGCCGCAGGATTGCTTCCTGACGCTG
CGCGGCATCAAGACGCTGGCGCTGCGGATGGAGCGCCATTGCGACAGCGCGGAGAAAGTGGCGGTCTGGCTGGCCGGACA
GCCGGCCGTGGCCAAGGTGTTCTACCCCGGACTCCCGGAGCATCCGGGGCATGAGCTGGCGAAGCGGCAGATGCGGCGCT
TCGGCGGCATCATCAGCATCCGGCTGCAGGACGACAGCCGCGAGGCGGCCAGCCGCGTCGCGCAGAGGCTGAAGCTGTTT
GCGCTGGCGGAGTCGCTGGGCGGGGTGGAGTCGCTGGTCAACCATAGCTACACGATGTCGCACGGCGGCATGCCGGCCGA
GCAGAAGGCGGCGCTGGGCATTGTCGAGGGCGGCCTGCGGCTGTCGATCGGCATCGAGGATCTGGACGACATCCTGGCGG
ACCTGGAGCAGGCGCTGCGCGATTGA

Protein sequence :
MKFATRAIHVGYDNAEHNRSVMPPLYQTSAFAFDHVGEDLRYAYARTGNPTRSALQDCLASLEEARHGLAFSSGMAAIDA
VLRACLKPGDEVIAVADLYGGAYRLLTRVMQPAGIKVSFVDLSDPARLEAAITPATRLLWLESPTNPLLGMVDIAALSAI
AHRHNVKVAVDNTFATPYLQQPLLLGADIVVHSATKYLGGHSDVLLGLVAVSDDKLHHDIRFLQNAAGAVPGPQDCFLTL
RGIKTLALRMERHCDSAEKVAVWLAGQPAVAKVFYPGLPEHPGHELAKRQMRRFGGIISIRLQDDSREAASRVAQRLKLF
ALAESLGGVESLVNHSYTMSHGGMPAEQKAALGIVEGGLRLSIGIEDLDDILADLEQALRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-70 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-71 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-57 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB NP_903719.1 cystathionine gamma-synthase BAC0207 Protein 2e-70 47