Gene Information

Name : CV_3965 (CV_3965)
Accession : NP_903635.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Virulence
Product : ClpA/B-type chaperone
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : 3.4.21.92
Position : 4286490 - 4289117 bp
Length : 2628 bp
Strand : -
Note : identified by sequence similarity; ORF located using Blastx/COG0542

DNA sequence :
CTGAAATCCCTGATAGACCGGTTGACGCCCACCGCGCGCCAGGCCATCGAGCAGGCCGCCAGCCGCGCGCTGGCCCGCAC
CCACTTCGAGATCGAGATCGAGCATGTGCTGCTGGCGATGTTCGATCAGGACGACAATGCCGCGCTGGCGGCGCTGCGCG
CGCTGGGCGCGGACCTGGGCCGCGTCGAGCGCGAGCTGGACGCCGCGCTGGACAACTTCCGCAGCGGCAATACCCGCAAT
CCGGTGCTGTCGTCGTGGCTGCCCAAGTGGCTGGAAAAGGCCTGGCTGCTGGCCAGCGCCGAGCACGGCCAGGACAGTGT
CTCCACGTTGGACTTGCTGCTGGCGCTGTGGCAGGACGACGCCCTGCGCGGCGCGCTGCAGTCCGGCGCGCCGGCATTGG
CGCGCCAGGATGCCGGCAGGCTGTCCGGCGCCTACGCCGCGCTGCGCCAGCACGGCGGCGAGGCGGCGGGCGGCGAGCAG
CCGTCGGCCGCGGCAGACGAGGGCGAAGGCGAGGCGCCGGCCGCGCCGCAGGGCAAGCGCGGCGGCGCCGCGCTGGACAA
GTACACGATAGACCTGACCGCGCAGGCCAAGGCCGGCAAGATCGACCCCATCCTGGGCCGCGATGTCGAAATCCGCCAGA
TGATAGACATCCTGATGCGCCGCCGGCAGAACAATCCCATCCTCACCGGCGAGCCGGGCGTGGGCAAGACCGCGGTGGTG
GAAGGCTTGGCGCGCAAGATCGTGCTGGGCGAGGTGCCGCCGGTGCTGTCCGGCGTCACGCTGCGCACGCTGGACCTGGG
CCTGCTGCAGGCCGGCGCCAGCGTCAAGGGCGAGTTCGAGAACCGCCTGCGCCAGGTGATAGACGAGGTCAAGGCCAGCC
CGGTGCCCATCATCCTGTTCATCGACGAGGCGCACACCCTGATCGGCGCCGGCGGCGCGGCCGGCCAGAACGACGCGGCC
AACCTGCTGAAACCGGCGCTGGCGCGCGGCGAGCTGCGCACCATCGCGGCGACGACCTGGGCCGAGTACAAGAAGTATTT
CGAGAAGGACGCCGCGCTGGCGCGCCGCTTCCAGGTGGTGAAGGTCGAAGAGCCGGCGCCGGAAATCGCCGTGCAGATGG
TGCGCGGCCTGACCGACGCGATGGCCAAGCACCACAAGGTGGAAATCCTCAACGAGGCGGTGGCCGCCGCAGTGCAGCTG
TCCAGCCGCTACATCGCCGGCCGCCAGCTGCCGGACAAGGCGATCAGCGTGCTCGACACCGCTTGCGCCCGCGTCGCGCT
GTCGCGCGCCGGCAAGCCGGGGCCGATCGAGGACGTGACGGTGCTGATAGACAACATCGACCGCGAAACCGCCGCGCTGG
AGCGCGAGGAAGGCCACGCCGAGCGCATCGCCGAGCTGCAGGCGCAGCGCGCCAAGCTGGAGCAGGATCTGGCCGCGCTG
CATCAGGCCTGGGAGGCGCAGCAGAAGCTGATCGAAGAGATAGACGAGCTGAAGGCGGCCAAGGACGAGGCCAAGCCGGC
CAAGGGCAGGAAGCTCAGCCCGCTGCAGGCCAAGCGCAAGGAATTGCGCGAGTTGCAGAAGCATCAGCCGCTGGCGTTCG
AATGCGTGGACGAGAGCGTGATCGCCGACGTGATCGCCGGCTGGACCGGCATCCCGCTGGGCCGCATGGTCAGCAACGAG
CTGGAGCAGGTGCAGAAGCTGGCCAAGCTGCTGGCCGAGCGCGTGATCGGCCAGGACCACGCGTTGGAGCAGATCGCCGA
GCGGGTGCAGATCGCCAAGGCCAATCTGGAAGATCCCGGCAAGCCCAAGGGCGTATTCCTGCTGGTGGGCCCGTCCGGCG
TCGGCAAGACCGAGACCGCGCTGGCGCTGGCCGAGGCGCTGTACGGCGGCGAGCGCAATCTGATCACCATCAACATGTCC
GAATACCAGGAAGCGCACAGCGTGTCCGGCCTGAAGGGCTCGCCCCCGGGTTATGTCGGCTACGGCGAGGGCGGCGTGCT
GACCGAGGCGGTGCGCCGCAAGCCGTACTCCGTCGTGCTGCTGGATGAAGTGGAGAAGGCGCACCCGGACGTGCTGGAGC
TGTTCTTTCAGGTATTCGACAAGGGCGTGCTGGAGGATAGCGAAGGCCGCGAGGTGGACTTCAAGAACACCATCATCCTG
CTGACGTCCAACGCCGGCACCGATCTGGTGATGCGCGCCTGCGAGCACGGCGTGACGGTGGAGGACGAGACCCGCGACCC
GACCGCGGAAGACCTGGTGGAAATCCTGCGCCCGACGCTGCAGAAGACCTTCAAGCCGGCTTTCCTCGGCCGCCTGACCA
TCGTGCCTTACTTCCCGATCAGCGACGACGTGCTGCGCGCCATCGTCGGCCTGAAGCTGGACAAGATCCGCCGCCGCATC
GCCGACAACCACGGCGCCCAGGTCGAGTTCCCGGAAGAACTGGCCGATCAGATGGCCGCGCGCTGCCTGGACGTGGACAG
CGGCGCGCGCAACGCCGACGCCATCCTCACCCGCACGCTGCTGGCGCAGATCTCCAACGACCTGCTGTCGCGTATGGCCA
GCGGCAAACCGGTGAAGAAGATCGCCGTCGCGCTGAAGGGCGAGCAGGTCAAGGTGAAGGTGAGTTAA

Protein sequence :
MKSLIDRLTPTARQAIEQAASRALARTHFEIEIEHVLLAMFDQDDNAALAALRALGADLGRVERELDAALDNFRSGNTRN
PVLSSWLPKWLEKAWLLASAEHGQDSVSTLDLLLALWQDDALRGALQSGAPALARQDAGRLSGAYAALRQHGGEAAGGEQ
PSAAADEGEGEAPAAPQGKRGGAALDKYTIDLTAQAKAGKIDPILGRDVEIRQMIDILMRRRQNNPILTGEPGVGKTAVV
EGLARKIVLGEVPPVLSGVTLRTLDLGLLQAGASVKGEFENRLRQVIDEVKASPVPIILFIDEAHTLIGAGGAAGQNDAA
NLLKPALARGELRTIAATTWAEYKKYFEKDAALARRFQVVKVEEPAPEIAVQMVRGLTDAMAKHHKVEILNEAVAAAVQL
SSRYIAGRQLPDKAISVLDTACARVALSRAGKPGPIEDVTVLIDNIDRETAALEREEGHAERIAELQAQRAKLEQDLAAL
HQAWEAQQKLIEEIDELKAAKDEAKPAKGRKLSPLQAKRKELRELQKHQPLAFECVDESVIADVIAGWTGIPLGRMVSNE
LEQVQKLAKLLAERVIGQDHALEQIAERVQIAKANLEDPGKPKGVFLLVGPSGVGKTETALALAEALYGGERNLITINMS
EYQEAHSVSGLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVLELFFQVFDKGVLEDSEGREVDFKNTIIL
LTSNAGTDLVMRACEHGVTVEDETRDPTAEDLVEILRPTLQKTFKPAFLGRLTIVPYFPISDDVLRAIVGLKLDKIRRRI
ADNHGAQVEFPEELADQMAARCLDVDSGARNADAILTRTLLAQISNDLLSRMASGKPVKKIAVALKGEQVKVKVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 4e-154 51
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-132 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 9e-133 43
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-96 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CV_3965 NP_903635.1 ClpA/B-type chaperone VFG2076 Protein 2e-177 52
CV_3965 NP_903635.1 ClpA/B-type chaperone VFG2084 Protein 7e-141 44
CV_3965 NP_903635.1 ClpA/B-type chaperone VFG0079 Protein 4e-103 43