Gene Information

Name : guaA (CV_3465)
Accession : NP_903135.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3759515 - 3761092 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGACAAGATCCTCATTCTCGACTTCGGCTCCCAGGTCACCCAGCTGATCGCCCGCCGCGTACGCGAAGCTCACGTTTA
CTGTGAGCTTCATTCTTTCGACATGCCCATCGAAGAGATCCAGGCCTTCGCGCCCAAGGCCATCATCCTGTCCGGCGGCC
CCAACTCGGTGTATGAATCCGACTACCAGGCCGATCCCAAGCTGTTCGAGCTGGGCGTGCCGGTGCTGGGCATCTGCTAC
GGCATGCAGTTCATGGCCCAGACCCTGGGCGGCAAGGTGGAAAGCGGCGACAAGCGCGAGTTCGGCTACGCCCAGATCAA
GGCCCGCCACCACTCCAAGCTGCTGGAAGGCCTGCAGGACCAGATCGACGACGCCGGCAACGGCTTCCTCGACGTGTGGA
TGAGCCACGGCGACAAGGTGACCCAGCTTCCGGCCGGCTTCCAGGTGATCGCCGAGACCCCGTCCTGCCCGTACGCGGCG
ATGGCTGACGAAGCCCGCGGCTTCTACGGCGTGCAGTTCCACCCGGAAGTGACCCACACCAAGCGCGGCACCGAGATGAT
CCACCGCTTCGTGCTGCACGTGGCCGGCTGCAAGCCCAGCTGGACCATGCCCAACTACATCGACGAAGCGGTGAAGAAGA
TCCGCGAGCAAGTCGGCGACGAAGAAGTCATCCTCGGCCTGTCCGGCGGCGTGGACTCCTCGGTGGCCGCCGCGCTGATC
CACCGCGCCATCGGCGACCAGCTGACCTGCGTCTTCGTCGACCACGGCCTGCTGCGCCTGAACGAAGGCAAGATGGTGAT
GGAAATGTTCGCCCAGAACCTGGGCGTCAAGGTGGTCCACGTGCAGGCCGAGGCCGACTTCATGGCCAAGCTGGCCGGCG
AGACCGACCCGGAGAAGAAGCGCAAGATCATCGGCGCGGAATTCATCGAAGTGTTCGACCGCGAATCCGGCAAGCTGACC
AACGCCAAGTGGCTGGCCCAGGGCACCATCTATCCGGACGTGATCGAATCGGCCGGCGCCAAGACCAAGAAGGCGCACAC
CATCAAGAGCCACCACAATGTGGGCGGCCTGCCGGAAGACATGAACCTGAAGCTCTTGGAGCCGCTGCGCGAGCTGTTCA
AGGACGAAGTGCGCCAGCTGGGCGTAGCGCTCGGCCTGCCGCACGACATGGTCTACCGCCACCCGTTCCCGGGCCCGGGC
CTGGGCGTGCGCATCCTCGGCGAAGTGAAGAAGGAATACGCGGATCTCTTGCGCCAGGCCGACGCCATCTTCATCGAAGA
GCTGCGCAACACCGTGGACGAGAAGACCGGCAAAAACTGGTACGAGCTGACCAGCCAGGCCTTCGCCGTGTTCCTGCCGG
TGAAGTCCGTCGGCGTGATGGGCGACGGCCGCACCTACGACTACGTGGTGGCATTGCGCGCCGTGGTGACCAGCGACTTC
ATGACCGCGCACTGGGCCGAGCTGCCGTACAGCCTGCTGGGCCGCGCCTCCAACCGCATCATCAACGAAGTCCGCGGCAT
CAACCGCGTGGTCTACGACGTCAGCGGCAAGCCGCCAGCGACCATCGAGTGGGAATAA

Protein sequence :
MDKILILDFGSQVTQLIARRVREAHVYCELHSFDMPIEEIQAFAPKAIILSGGPNSVYESDYQADPKLFELGVPVLGICY
GMQFMAQTLGGKVESGDKREFGYAQIKARHHSKLLEGLQDQIDDAGNGFLDVWMSHGDKVTQLPAGFQVIAETPSCPYAA
MADEARGFYGVQFHPEVTHTKRGTEMIHRFVLHVAGCKPSWTMPNYIDEAVKKIREQVGDEEVILGLSGGVDSSVAAALI
HRAIGDQLTCVFVDHGLLRLNEGKMVMEMFAQNLGVKVVHVQAEADFMAKLAGETDPEKKRKIIGAEFIEVFDRESGKLT
NAKWLAQGTIYPDVIESAGAKTKKAHTIKSHHNVGGLPEDMNLKLLEPLRELFKDEVRQLGVALGLPHDMVYRHPFPGPG
LGVRILGEVKKEYADLLRQADAIFIEELRNTVDEKTGKNWYELTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVVTSDF
MTAHWAELPYSLLGRASNRIINEVRGINRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-137 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-137 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-137 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-114 50