Gene Information

Name : kdsB (CV_3344)
Accession : NP_903014.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 3642200 - 3642955 bp
Length : 756 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAACGGCTTCACGGTGGTGATCCCGGCGCGGATGGCGTCCAGCCGTCTGCCTGGCAAGCCGCTGGCAGACATCGCCGG
CAAGCCCATGGTGGTGCGCGTGGCGGAGCAGGCGGCGAAGAGCCGCGCCGCCCGCGTCGTGGTCGCCACCGACCACGCCG
ACATCCTGGCCGCCTGCGCCGCGCACGGCGTCGAGGCGGTGCTGACGCGCGAAGACCACGCCAGCGGCACCGATCGCCTA
GCCGAAGTGGCCGCCAAGCTGGCGTTGCCGGACGACGCGCTGGTGGTCAACGTGCAGGGCGACGAGCCGCTGATCCAGCC
TGAGCTGATCAACCGGCTGGCCGAGCTGCTGGCCGGCGCCGACGCGCCGGTGGCGACCCTGGCGCACGCGCTGCACGACG
CGGCCGACCATTTCAATCCCAATGTGGTGAAAGTGGCGCTGGACAAGCATGGCCGCGCGCTGTACTTCAGCCGCGCGCCG
ATTCCCTACGCCCGCGACGCCTACGCCGCCGACCGCTCGGCGTTGCCGGCCGGACTGCCGGTTTACCGCCATATCGGCAT
GTACGGTTACCGGGCCGGTTTCCTGGCTGCCTATGCAGGCCTGGAGCCGGGGCCGCTGGAGCAATACGAAGCGCTGGAAC
AATTGCGCGTGCTCTGGCATGGTTACGGCATCGCGGTGGCATTGGCGGACGAGGCGCCGGCCGCCGGCGTGGACACGCCG
GAAGACCTGGAACGGGTGCGCCGGCTGTTCGCCTGA

Protein sequence : 
MNGFTVVIPARMASSRLPGKPLADIAGKPMVVRVAEQAAKSRAARVVVATDHADILAACAAHGVEAVLTREDHASGTDRL
AEVAAKLALPDDALVVNVQGDEPLIQPELINRLAELLAGADAPVATLAHALHDAADHFNPNVVKVALDKHGRALYFSRAP
IPYARDAYAADRSALPAGLPVYRHIGMYGYRAGFLAAYAGLEPGPLEQYEALEQLRVLWHGYGIAVALADEAPAAGVDTP
EDLERVRRLFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-26 44
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-26 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 9e-26 43