Gene Information

Name : metZ (CV_2725)
Accession : NP_902395.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Resistance
Product : O-succinylhomoserine sulfhydrylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2954870 - 2956054 bp
Length : 1185 bp
Strand : -
Note : catalyzes the conversion of O-succinylhomoserine into homocysteine

DNA sequence :
ATGGCATCCGACGCGCCGCATCTTCCGCTGCACCCTGAAACCCTGGCCATCCGGGCCGGGTTGGAAACCAGCCAGTTCAA
CGAGCACAGCCAGGGCCTGTTCCTGACGTCCAGCTTCACCTACGAATCGGCCGCGCAGGCGGCGGCGATGTTCCTGGGCG
AGATCGACGGCTACACCTATTCCCGCTTCACCAATCCGACCGTCGCCGCGTTCCAGCATAGGCTGGCGCAGATGGAGGGC
GGGGAGCGCGCCATCGCCACCGCCACCGGCATGGCGGCGATCCAGGCCATCATGATGACTTTGCTGCAGGCTGGCGACCA
CATCGTGTCGTCGCAAAGCCTGTTCGGCTCCACCACCAATCTGTTCGCCAACCAGTTGGCCAAGTTCGCCGTGGCCACCG
ACTTCGTCGACGCGCGCGACCTGTCCGCCTGGCGGGAGGCGCTGCGGCCGAACACCAAGCTGCTGTTCCTGGAGACGCCG
TCCAATCCCTTGACCGAAGTGGCCGACATCGCGGCCATCGCCGACATCGCCCACGCGCATGGCGCGCTGCTGGTGGTGGA
CAACAGCTTCTGTTCGCCGGCCTTGCAGCAGCCGTTGAAACTGGGCGCCGATCTGGTCATGCATTCCGCCACCAAGTTCA
TCGACGGCCATGGCCGGGTGATGGGCGGGGCGGTGGTCGGCAGCGACAAGCTGGTCGAGCAGGTCTATTTGCACGTGCGC
GCCGCCGGTCCCTCGCTGGCGCCGTTCAATGCCTGGACGCTGCTGTCCGGTTTGGAGACGCTGCACCTGCGGATGGAGAA
GCACAGCGCCAACGCGCTGGAGCTGGCGCGCTGGCTGGAGGCGCAGCCCAATGTGGAGCGCGTCTATTACCCGGGCCTGG
AGAGCCACCCCCAGCACGAGCTGGCGCTGCGCCAGCAGAAGAGCGGCGGAGCGGTGGTGTCCTTCGTGGTCAAGGGCGGC
CGCAAGGCCGCGTGGAAAGTGGTGGACGCGGTCAGGGTGATCTCGCGCACCGCCAATCTGGGCGATGTGAAAACCACCCT
CACTCATCCGGCCAGCACCACCCACGCCCGCGTGACGCAGGAGGCGCGCGAGCGCGCCGGCATCGTCGAGGGGCTGTTGC
GCGTCAGCGTCGGCCTGGAAAATGTACGGGACCTTCAACAAGATCTGTTGCGGGGCCTTGACTAA

Protein sequence :
MASDAPHLPLHPETLAIRAGLETSQFNEHSQGLFLTSSFTYESAAQAAAMFLGEIDGYTYSRFTNPTVAAFQHRLAQMEG
GERAIATATGMAAIQAIMMTLLQAGDHIVSSQSLFGSTTNLFANQLAKFAVATDFVDARDLSAWREALRPNTKLLFLETP
SNPLTEVADIAAIADIAHAHGALLVVDNSFCSPALQQPLKLGADLVMHSATKFIDGHGRVMGGAVVGSDKLVEQVYLHVR
AAGPSLAPFNAWTLLSGLETLHLRMEKHSANALELARWLEAQPNVERVYYPGLESHPQHELALRQQKSGGAVVSFVVKGG
RKAAWKVVDAVRVISRTANLGDVKTTLTHPASTTHARVTQEARERAGIVEGLLRVSVGLENVRDLQQDLLRGLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-54 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metZ NP_902395.1 O-succinylhomoserine sulfhydrylase BAC0207 Protein 2e-63 45