Gene Information

Name : spaS (CV_2621)
Accession : NP_902291.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Virulence
Product : surface presentation of antigens protein SpaS
Function : -
COG functional category : N : Cell motility
COG ID : COG1377
EC number : -
Position : 2829334 - 2830395 bp
Length : 1062 bp
Strand : -
Note : Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins

DNA sequence :
ATGTCGTCCAACAAGACCGAGAAACCCACGCGCAAGAAGCTGCAGGACGCGGCCAAAAAGGGCCAGTCCTTCAAGAGCCG
CGACCTGGTGGTGGCCTGCCTGACGCTGTGCGGCGTGGCTTACCTGGTGTCGTTCGGCTCGCTGGTCGAGTTGATGGGCA
TTTTCCGCCAGGCCCTGGCCGGCGGTTTCCAGCTGGACATGCGCGGCTACGCCCAGGCGGTGTTCTGGCAAGGGCTGAAA
TTGCTGCTGCCCATCTTCCTGCTGTGCGTGGCCGCCTCGGCGCTGCCGGTGTTGCTGCAGACCGGCTTCGTGCTGGCCAG
CGAGGCGCTCAAGCTCAATCTGGAGGCGCTCAACCCGATCAACGGCTTCAAGAAGCTGTTCAGCCTGCGCACGGTGAAGG
AGGCGGTGAAGGCGCTGCTGTACCTGGCCAGCTTCGTGGTGGCCGTGGCGCTGATCTGGCGCAAGCACAAGGCGCTGCTG
TTCGCCCAGCTTAACGGCAGCGTCATGGACATCGCCGCCGTGTGGCGAGAGCTGCTGCTGTCTCTGGTGCTGACCTGCCT
GGGCTGCATCGTGCTGATCCTGATTCTGGACGCGCTGGCCGAGTACTTCCTGTTCATGAAGGACATGAAGATGGACAAAC
AGGAAGTGAAGCGCGAGATGAAGGAGCAGGAAGGCAATCCCGAAATCAAGTCGCGCCGGCGCGAGGCGCATTTCGAGCTG
CTGTCCGAGCAGGTGAAGTCGGACGTGGAGAACTCCAGGCTGATCATCGCCAACCCCACCCATATCGCCATCGGCATTTA
TTTCCGGCCCGAGCTGGTGCCCATCCCCTTCGTGTCGGTGATGGAAACCAACCAGCGCGCGCTGGCGGTGCGCGCCTACG
CGGAGAAGGTCGGCGTGCCGGTGGTGCGCGACGTGCCGCTGGCGCGGCGCATCCTGGCCAGCCACCGCCGCTATTCCTTC
ATCAACCTGGAAGAGGTGGACGAGGTGCTGCGCCTGCTCGAATGGCTGGAACAGGTGGAAAACGCCGGTCGTCCGGACGA
TGAGCCGTCCGGCGGGCCATGA

Protein sequence :
MSSNKTEKPTRKKLQDAAKKGQSFKSRDLVVACLTLCGVAYLVSFGSLVELMGIFRQALAGGFQLDMRGYAQAVFWQGLK
LLLPIFLLCVAASALPVLLQTGFVLASEALKLNLEALNPINGFKKLFSLRTVKEAVKALLYLASFVVAVALIWRKHKALL
FAQLNGSVMDIAAVWRELLLSLVLTCLGCIVLILILDALAEYFLFMKDMKMDKQEVKREMKEQEGNPEIKSRRREAHFEL
LSEQVKSDVENSRLIIANPTHIAIGIYFRPELVPIPFVSVMETNQRALAVRAYAEKVGVPVVRDVPLARRILASHRRYSF
INLEEVDEVLRLLEWLEQVENAGRPDDEPSGGP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spaS NP_461808.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 7e-104 69
spaS NP_457281.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 2e-104 69
spaS NP_806490.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 2e-104 69
spaS YP_217806.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 2e-103 69
spaS AAS66868.1 SpaS Not tested SSR-2 Protein 3e-93 63
ECs3721 NP_311748.1 surface presentation of antigens protein SpaS Not tested LIM Protein 3e-76 56
ysaU AAS66849.1 YsaU Not tested SSR-1 Protein 1e-60 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spaS NP_902291.1 surface presentation of antigens protein SpaS VFG0548 Protein 3e-104 69
spaS NP_902291.1 surface presentation of antigens protein SpaS VFG2452 Protein 4e-62 50
spaS NP_902291.1 surface presentation of antigens protein SpaS VFG1015 Protein 4e-65 48
spaS NP_902291.1 surface presentation of antigens protein SpaS VFG1770 Protein 2e-53 42