Gene Information

Name : CV_2603 (CV_2603)
Accession : NP_902273.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.1.14
Position : 2813261 - 2814595 bp
Length : 1335 bp
Strand : +
Note : identified by sequence similarity; ORF located using Glimmer/GeneMark/Blastx/COG1157/TC:3.A.6.1.1

DNA sequence :
ATGCGGCTTCCAGACATCCGTCTCATCGAAAACACGCTGCGGGAACGACTGACCCTGGCCCCGGCACCGCCTGGGCAACG
CTCCGGCGTGGAACTATTCGGCCGGGTCACGGAAATCGGCCCCACCCTGCTGAAAGCCTCGCTGCCCGGCGCCAGCCTGT
CGGAGTTATGCCGGCTGGAACCTTCCGGCATCGAGGCCGAAGTGGTCGCCGTCACTGGAGACCACGTGATGCTATCGCCA
TTCAAAGAACCGCTGGGCGTCACCATCGGCAGCCGGGTCAGGCCTTCCGGCAGCCCACACCAGTTGCGCCTGGGCGATTT
CCTGCTGGGGCGGGTCGTCGACGGACTCGGCCGTCCGCTGGATGGCGACGAGCTTCCCGCCGACAGCGAGCTGCGCAGCC
TGGACGGACCCGCGCCCAATCCGCTGACCCGGCAATTGATAGACACGCCGCTGCCGCTGGGCGTCAGGGCCATCGATGGC
TTGCTGACTTGCGGCATGGGTCAGCGCATCGGCATCTTCGCCGCGGCGGGCGGCGGCAAGAGCACGTTGCTGGGCATGAT
CTGCGACGGCAGCCTTGCCGACGTCATCGTGCTGGCGCTGATTGGCGAACGGGGCCGTGAGGTGCGTGAATTCCTCGAAC
ATACCTTGTCGGAGGAGGCTCGGTCCCGCTCCATCGTAGTGGTGTCGACATCGGACCGTCCGGCGCTGGAACGGCTGAAA
GCCGCCTACACCGCCACCGCCATCGCCGAGCATTTCCGCGACCAGGGTAAGAACGTACTGTTAATGATGGACTCCCTGAC
CCGTTTTGCCCGCGCCTCGCGCGAGATCGGCCTGGCCGCGGGAGAACCCGCCGCTGCCGGCGGCTATCCGCCAAGCTTCT
TCGCCCGCCTGCCCCGCCTGCTGGAACGGGCCGGTCCGGCTGAAACCGGCAGCATCACCGGCATCTACACCGTTCTGGTC
GAGGGCGACAACCTCAACGAACCAGTCGCGGATGAAGTCCGCTCCATTCTGGATGGCCACATCGTGCTGTCGCGCAAGCT
GGCCGAGACCAACCACTACCCGGCCATCGATATCGGCGCCAGCGTCAGCCGGATCATGGGCCAGATCGTCAGCGCCGAAC
ACCGCCAACAGGCCGGCAAATTGCGCCGGTTGATGGCCGCGTACAAGGAAATCGAGCTATTGGTCCGGGTGGGTGAGTAC
CAACCTGGCCAGGATGCAGAAGCGGACGAGGCGCTGGAACGCAAGGACGCGATCCGGCAATTCCTTTGCCAATCCGTCAC
CGAAAAGAACGACTTTGAAGAAACACTGGAACAGCTATGGCAGACAGTCGACTGA

Protein sequence :
MRLPDIRLIENTLRERLTLAPAPPGQRSGVELFGRVTEIGPTLLKASLPGASLSELCRLEPSGIEAEVVAVTGDHVMLSP
FKEPLGVTIGSRVRPSGSPHQLRLGDFLLGRVVDGLGRPLDGDELPADSELRSLDGPAPNPLTRQLIDTPLPLGVRAIDG
LLTCGMGQRIGIFAAAGGGKSTLLGMICDGSLADVIVLALIGERGREVREFLEHTLSEEARSRSIVVVSTSDRPALERLK
AAYTATAIAEHFRDQGKNVLLMMDSLTRFARASREIGLAAGEPAAAGGYPPSFFARLPRLLERAGPAETGSITGIYTVLV
EGDNLNEPVADEVRSILDGHIVLSRKLAETNHYPAIDIGASVSRIMGQIVSAEHRQQAGKLRRLMAAYKEIELLVRVGEY
QPGQDAEADEALERKDAIRQFLCQSVTEKNDFEETLEQLWQTVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-113 61
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-106 59
escN YP_003223475.1 translocator EscN Virulence LEE Protein 4e-107 59
escN CAC81862.1 EscN protein Virulence LEE II Protein 7e-107 59
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-107 59
escN AAK26715.1 EscN Virulence LEE Protein 2e-106 59
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 9e-107 59
escN AAL57542.1 EscN Virulence LEE Protein 2e-106 59
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-109 58
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-109 58
escN NP_290268.1 hypothetical protein Virulence LEE Protein 7e-107 58
ECs4568 NP_312595.1 EscN Virulence LEE Protein 7e-107 58
escN AAC31513.1 L0034 Virulence LEE Protein 6e-107 58
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 6e-107 58
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-106 58
escN AAC38383.1 EscN Virulence LEE Protein 2e-107 58
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-106 57
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-97 56
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-97 56
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-97 56
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-101 56
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-101 56
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-101 56
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-101 56
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-101 56
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-96 55
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-96 55
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-97 55
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-95 55
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-95 55
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-96 55
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 6e-81 51
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-79 51
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 9e-84 51
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 9e-84 51
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 6e-88 51
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 5e-88 51
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-88 51
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-93 51
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 8e-88 50
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 5e-81 49
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-78 49
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-78 49
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 6e-70 46
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-74 44
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 5e-74 44
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-74 44
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-74 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-69 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 9e-69 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CV_2603 NP_902273.1 type III secretion system ATPase VFG0192 Protein 8e-108 59
CV_2603 NP_902273.1 type III secretion system ATPase VFG0390 Protein 9e-111 58
CV_2603 NP_902273.1 type III secretion system ATPase VFG0730 Protein 1e-107 58
CV_2603 NP_902273.1 type III secretion system ATPase VFG0812 Protein 3e-107 58
CV_2603 NP_902273.1 type III secretion system ATPase VFG0515 Protein 1e-101 56
CV_2603 NP_902273.1 type III secretion system ATPase VFG0048 Protein 2e-103 56
CV_2603 NP_902273.1 type III secretion system ATPase VFG2144 Protein 9e-94 53
CV_2603 NP_902273.1 type III secretion system ATPase VFG1254 Protein 5e-81 52
CV_2603 NP_902273.1 type III secretion system ATPase VFG2499 Protein 2e-71 49
CV_2603 NP_902273.1 type III secretion system ATPase VFG2331 Protein 1e-71 46
CV_2603 NP_902273.1 type III secretion system ATPase VFG1778 Protein 1e-72 45
CV_2603 NP_902273.1 type III secretion system ATPase VFG2459 Protein 5e-71 44
CV_2603 NP_902273.1 type III secretion system ATPase VFG0555 Protein 2e-74 44
CV_2603 NP_902273.1 type III secretion system ATPase VFG1008 Protein 6e-66 43