Gene Information

Name : escV (CV_2602)
Accession : NP_902272.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Virulence
Product : secretion system apparatus protein SsaV
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 2811208 - 2813259 bp
Length : 2052 bp
Strand : +
Note : with SsaC forms part of a protein export system across the inner and outer cell membranes; part of the Salmonella pathogenicity island 2; part of the type III secretion system

DNA sequence :
ATGAACCAGATCAAATCCTTCCTGATGATGGCGGCCGGGCGACAGGATATCGTCCTGGCGGTCATGCTGCTGGTGGCCGT
GTTCATGATGATCATTCCATTGCCTACCGGCCTGGTGGACTTCATGATCGCGCTCAATCTGATGATCGCCGTCATCCTGC
TGATGATGTCGCTGTACATCCGGGAGCCGCTGGAATTTTCAGCCTTCCCCTCGGTATTGCTGATCACCACCCTGTACCGC
TTGGCGCTGACCATCAGCACCACCCGGCTGATCCTGCTGCAAGCAGACGCCGGTGAAATCGTCTACACCTTCGGCAGTTT
CGCGGTGGGCGGCAACCTCGGCGTGGGCTTGATCGTATTCGTGATCATCACCGTGGTGCAATTCATCGTCATCACCAAGG
GTTCGGAGCGGGTGGCGGAGGTCAGCGCCCGCTTCTCGCTAGACGCCATGCCCGGCAAGCAGATGAGCATAGACGGCGAC
ATGCGCGCCGGGGTCATAGACGCCAACGAGGCGCGCCGCCTGCGCGGACTGGTGCAAAAGGAAAGCCAGCTGTACGGCGC
GATGGATGGTGCGATGAAATTCGTCAAGGGCGACGCCATCGCCGGCATCATCATCATCCTGGTGAACATCCTGGGCGGCA
CCGCCATCGGCGTGATGATGCACGGCATGAGCGCGAGCGCGGCCCTGTCCACCTATGCCATCCTGTCGATCGGCGATGGT
TTGATCGGCCAGATACCGGCGCTGCTGATTTCCATCACCGCCGGCACCATCGTGACCCGGGTGCCGGGCGAGCAAAGACT
GAACCTGGCCAGCGATTTGACCGACCAGATCGGCAAACAGCCGCAGGCCCTGCTGCTGGCCGCGTCGGTGCTGCTGGTTT
TCGCGCTGATTCCCGGCTTCCCAGCCATCTACTTCATCATTCTCGCCGCGATGGTCAGCGCCGCCGCATGGTGGGTGAAA
AAGCGCAAGCGTGCCGCCAGGAGCGACTCCACGGGCTCGCCCTCCTCCGAATCTGGAGCCGATGCCGGCGGCGAGACCGC
CAATATGTCGCCCGGCGCCACGCCGTTGATGATGCGCCTGTCGCCTGACCTTATCCGTTCCAGCCGCCTGCCGGCGCTGC
TGGACACCTTCCGGCACGGCAAGTTCGAGCAGTTGGGCATTCCACTCCCGGAAATCCAGCTGCAGAAGGACGCTTCACTG
GCTGCCGGCACATTGCAGATTCTGCTGTACCAAGAACCGGTGTTGACAGTTTCGCTGCCCGAGCGGCTATTGCTGGCCGA
CATCGCCTCGCCCAAGCTGCCGCAATCCGAGCAGACCGACAAGCTGCCTTTCGGCAATCTGAGCCTGCAGTGGCAGAGCC
CGACGCAAAAAGAAGCCTTGTCCGCCATCGGCGTCCAGCTGCATCAGGATGAAGACCGGATCGTTCATTGCCTGTCCATC
ATCATCGACCGCTACGCCGCCGAATTCGTCGGTGTGCAGGAAACCCGCTTCCTGATGGATGCGATGGAGTCGAAATACGC
CGAGCTGATCAAGGAAGTGCAACGCCAGCTGCCCATCGGCCGCATCGCCGACGTGCTGCAGCGCCTGGTGGCGGAAGGCG
TGTCCATCCGCGATCTGCGCAGCGTGTTCGAGGCCTTGATCGAATGGGCGCCGCGGGAAAAAGACCCGGTCATGTTGCTG
GAATACGTCCGCATGGGCCTGCGCCGGCACATCGTCACGCGTTACCGCGCCGGACAACCCTGGATCAGCGGCTGGATGAT
AGGCGACACCATAGAAGGCATGGTGCGCGAAGCGATACGGCAGACTTCGGCGGGCTCCTACTCGGCGCTGGATCCTGAGC
ATAACCAGGCCATCATGAGCTGCATCCGCGAGGCCGTCGGCGACGCGGAGAAACGCAATCAGGTGCTGATCACGGCGATC
GACGTGCGGCGATTCCTGCGCAAGGTGGTAGAGAGAGAATTCTTCAACTTGCACGTGTTGTCGTTTCAGGAAATCGGCGA
AGAAGCGGAATTGCGCGTGGTCGGCAATATCGACCTGATCGGGGAGTATTAG

Protein sequence :
MNQIKSFLMMAAGRQDIVLAVMLLVAVFMMIIPLPTGLVDFMIALNLMIAVILLMMSLYIREPLEFSAFPSVLLITTLYR
LALTISTTRLILLQADAGEIVYTFGSFAVGGNLGVGLIVFVIITVVQFIVITKGSERVAEVSARFSLDAMPGKQMSIDGD
MRAGVIDANEARRLRGLVQKESQLYGAMDGAMKFVKGDAIAGIIIILVNILGGTAIGVMMHGMSASAALSTYAILSIGDG
LIGQIPALLISITAGTIVTRVPGEQRLNLASDLTDQIGKQPQALLLAASVLLVFALIPGFPAIYFIILAAMVSAAAWWVK
KRKRAARSDSTGSPSSESGADAGGETANMSPGATPLMMRLSPDLIRSSRLPALLDTFRHGKFEQLGIPLPEIQLQKDASL
AAGTLQILLYQEPVLTVSLPERLLLADIASPKLPQSEQTDKLPFGNLSLQWQSPTQKEALSAIGVQLHQDEDRIVHCLSI
IIDRYAAEFVGVQETRFLMDAMESKYAELIKEVQRQLPIGRIADVLQRLVAEGVSIRDLRSVFEALIEWAPREKDPVMLL
EYVRMGLRRHIVTRYRAGQPWISGWMIGDTIEGMVREAIRQTSAGSYSALDPEHNQAIMSCIREAVGDAEKRNQVLITAI
DVRRFLRKVVEREFFNLHVLSFQEIGEEAELRVVGNIDLIGEY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 2e-154 58
ssaV NP_456114.1 putative type III secretion protein Virulence SPI-2 Protein 9e-131 52
ssaV NP_805085.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 9e-131 52
ssaV YP_216422.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 6e-131 52
ssaV NP_460379.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 6e-131 52
ssaV CAA70536.1 secretion system apparatus Virulence SPI-2 Protein 4e-131 52
escV AAC31514.1 L0035 Virulence LEE Protein 2e-122 50
escV ACU09459.1 EscV protein Virulence LEE Protein 2e-122 50
escV NP_290269.1 hypothetical protein Virulence LEE Protein 3e-122 50
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 3e-122 50
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 4e-122 49
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-122 49
escV AAK26714.1 EscV Virulence LEE Protein 3e-122 49
escV AAL57541.1 EscV Virulence LEE Protein 3e-122 49
escV CAI43875.1 EscV protein Virulence LEE Protein 2e-122 49
escV CAC81861.1 EscV protein Virulence LEE II Protein 6e-122 49
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 4e-122 49
escV YP_003223476.1 translocator EscV Virulence LEE Protein 3e-122 49
unnamed AAL06368.1 EscV Virulence LEE Protein 3e-121 49
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 2e-121 49
escV AAC38382.1 EscV Virulence LEE Protein 4e-122 49
lssD AAO18050.1 LssD Virulence TTSS locus Protein 3e-118 46
invA AAS66860.1 InvA Not tested SSR-2 Protein 2e-93 43
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 5e-103 43
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 5e-103 43
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 5e-103 43
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 5e-103 43
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 5e-100 42
XC_3013 YP_244081.1 HrcV protein Virulence Hrp PAI Protein 6e-77 41
hrcV NP_636603.1 protein HrcV Virulence Hrp PAI Protein 6e-77 41
hrcV YP_362156.1 HrcV protein Virulence Hrp PAI Protein 1e-77 41
hrcV AAP34346.1 HrcV Virulence Hrp PAI Protein 4e-78 41
hrcV NP_640760.1 HrcV protein Virulence Hrp PAI Protein 2e-78 41
hrcV NP_791229.1 type III secretion protein HrcV Virulence Hrp PAI Protein 1e-89 41
hrcV AAG33877.1 HrcV Virulence Hrp PAI Protein 2e-90 41
hrcV ABA47273.1 HrcV Virulence S-PAI Protein 3e-86 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
escV NP_902272.1 secretion system apparatus protein SsaV VFG0514 Protein 2e-131 52
escV NP_902272.1 secretion system apparatus protein SsaV VFG0813 Protein 1e-122 50
escV NP_902272.1 secretion system apparatus protein SsaV VFG0729 Protein 3e-122 49
escV NP_902272.1 secretion system apparatus protein SsaV VFG0064 Protein 7e-120 48
escV NP_902272.1 secretion system apparatus protein SsaV VFG0198 Protein 1e-115 47
escV NP_902272.1 secretion system apparatus protein SsaV VFG0384 Protein 7e-119 46
escV NP_902272.1 secretion system apparatus protein SsaV VFG0557 Protein 2e-103 43
escV NP_902272.1 secretion system apparatus protein SsaV VFG2126 Protein 2e-103 42
escV NP_902272.1 secretion system apparatus protein SsaV VFG1006 Protein 8e-98 41