Gene Information

Name : thiC (CV_0235)
Accession : NP_899905.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 243272 - 245170 bp
Length : 1899 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCGCCCGTGAACAAGCAGATGGTGGTGGACGCCGCCGCCATCCAGCCCTTGCCCAATTCCCGCAAGATTTACGT
CGAGGGCAGCCGCCCGGACATTCAAGTGCCGATGCGCGAGATCCGCCAGGCGGACACGCCGACCCAATTCGGCGGCGAAA
AAAACCCTCCCATCTTCGTCTACGACACTAGCGGCCCGTATAGCGATCCGGCCGCCCGCATCGACATCCAGAGCGGCCTC
GCGCCCTTGCGCGCCGCCTGGATCGCCCAGCGCGGCGATTGCGAGCAGCTCCCCGGCCTGTCCAGCGAATACGGCCGCGC
CCGCGAGGCCGACCCCAAGCTCGCCGAGCTGCGCTTCAATCTGCAGCGCAAGCCGCGCCGCGCCAAGGCCGGCCGCAACG
TGACGCAGATGCACTACGCCCGCCGCGGCATCGTCACGCCGGAGATGGAGTTCGTCGCCATCCGAGAGAACCTGAACCGC
CGCGCCTACGTAGAGTCGCTGCAGGCCGCCGGCAACCGGCGCCTGCTGGACTTGATGACGCGCCAGCACCAGGGCCAGAG
CTTCGGCGCCCATCTGCCCGAAGAGATCACGCCGGAGTTCGTGCGTGAGGAGATTGCCGCCGGCCGCGCCATCATCCCGG
CCAACATCAATCACCCGGAAAGCGAACCGATGATCATCGGCCGCAACTTTCTGGTGAAAATCAACGGCAATATCGGCAAT
AGCGCGGTAACGTCGTCGATATCCGAAGAAGTTGACAAGATGACCTGGGGCATCCGCTGGGGCGCGGACACCATCATGGA
CCTGTCCACCGGCAAGAACATCCACGAAACGCGGGAGTGGATTCTGCGCAACAGCCCGGTGCCGATCGGCACCGTGCCCA
TCTACCAGGCGCTGGAGAAGGTGAACGGCAAGGCCGAGGACCTGAGTTGGGAAATCTTCCGCGACACGCTGATCGAGCAG
GCCGAGCAGGGCGTGGACTACTTCACCATCCACGCCGGCGTGCGCCTGGCTTACGTGCCGATGACCGCCAACCGCATGAC
CGGCATCGTGTCGCGCGGCGGCTCCATCATGGCCAAGTGGTGTCTGGCGCATCACCGCGAGAACTTCCTCTACACCCACT
TCGAGGACATCTGCGAAATCATGAAGGCCTACGACGTGGCCTTCAGCCTGGGCGACGGCCTGCGGCCGGGCAGCGCCTGG
GACGCCAACGACGAGGCGCAGCTGTCGGAGTTGAAGACGCTGGGCGAGTTGACCGAGATCGCTTGGAAACACGATGTGCA
AGTGATGATAGAAGGCCCGGGCCATGTGCCGATGCAGCTGATCAAGGAGAATATGGACAAGGAGCTGGAATGGTGCCGCG
AAGCGCCGTTCTACACCCTGGGGCCGCTGACCACCGACATCGCGCCCGGCTACGACCACATCACTTCGGCCATCGGCGCG
GCGCAGATCGGCTGGTACGGCACCGCGATGCTGTGCTACGTGACGCAGAAGGAACACCTGGGCCTGCCGAACAAGCACGA
CGTGAAAGAGGGCATCATCACCTACAAGCTGGCGGCGCACGCGGCCGACCTGGCCAAGGGCCATCCCGGCGCGCAGATCC
GCGACAACGCGCTGTCCAAGGCGCGCTTCGAATTCCGCTGGGAGGACCAGTTCAACCTGGGCCTGGACCCGGACAAGGCG
CGCGACTTCCACGACGAGACCCTGCCCAAGGACAGCGCCAAGGTGGCGCACTTCTGCAGCATGTGCGGTCCGCACTTCTG
CAGCATGAAGATCACCCAGGATGTGCGCGAGTACGCGGCCAGCCAGGGCGTAGGCGAGCAGGACGCGCTGCGGCTGGGCA
TGCGGGAAAAGGCGATCGAATTCGTCAAGGGAGGCGGCAAGCTGTATGACAAGGTGTAA

Protein sequence :
MNAPVNKQMVVDAAAIQPLPNSRKIYVEGSRPDIQVPMREIRQADTPTQFGGEKNPPIFVYDTSGPYSDPAARIDIQSGL
APLRAAWIAQRGDCEQLPGLSSEYGRAREADPKLAELRFNLQRKPRRAKAGRNVTQMHYARRGIVTPEMEFVAIRENLNR
RAYVESLQAAGNRRLLDLMTRQHQGQSFGAHLPEEITPEFVREEIAAGRAIIPANINHPESEPMIIGRNFLVKINGNIGN
SAVTSSISEEVDKMTWGIRWGADTIMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVNGKAEDLSWEIFRDTLIEQ
AEQGVDYFTIHAGVRLAYVPMTANRMTGIVSRGGSIMAKWCLAHHRENFLYTHFEDICEIMKAYDVAFSLGDGLRPGSAW
DANDEAQLSELKTLGELTEIAWKHDVQVMIEGPGHVPMQLIKENMDKELEWCREAPFYTLGPLTTDIAPGYDHITSAIGA
AQIGWYGTAMLCYVTQKEHLGLPNKHDVKEGIITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDKA
RDFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREYAASQGVGEQDALRLGMREKAIEFVKGGGKLYDKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 75
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 74
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 74