Gene Information

Name : serS (CV_1375)
Accession : NP_901045.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1449771 - 1451054 bp
Length : 1284 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGACATCAATCTACTTCGTAATGACATCGAAGCGGTCGCCGCCCGTCTGGCCGGCCGCGGCTACACCCTGGACAC
CGCAGCGTTCAATCAGCTGGAATCCGAGCGCAAGTCCCTGCAATCCCGGATGCAGGAACTGCAAGCCAAGCGCAACGCCA
CTTCCAAGCAGATCGGCATCGCCAAGGGCAAGGGTGAAGATGTCTCCGCCATTCTGGCCGAAGTAGCCACCCTGGGTGAC
GAGCTGAAAGCCGCGGAACAGGCGTTCGACGGCGTGCAGGGCCAGCTGGACGCCTGGCTGATGTCCATCCCCAACCTGCC
GCACGAATCGGTGCCGGTGGGCAAGGATGAAAACGACAACGTGGAAGTGCGCCGCGTCGGCGTGCCGCGCCAGTTCGACT
TCGAAGTGAAAGACCACGTCGACGTCGGCGCCCCGCTGGGCCTGGATTTCGACACCGGCGCCAAGCTGTCCGGCGCGCGC
TTCACCGTGCTGAAGGGCGACATCGCCCGCCTGCACCGCGCCATCGCGCAGTTCATGCTGAACACCCACACCGGCAGCCA
CGGCTACCAGGAGCACTACACCCCGTACATCGTCAACGACACCGCGCTTTTGGGCACCGGCCAACTGCCGAAATTCGCCG
ACGACATGTTCAAGGTGACCCGCGGCGGCGACGAGTCCGCCGTGCCGCAATACCTGATTTCCACCTCGGAAGTGACGCTG
ACCAATACCGTCGCCGACACCATCCTGCAAGAGAGCGAGCTGCCGAAGAAGATGACCGCGCACTCGCCGTGCTTCCGCTC
CGAGGCCGGCAGCTACGGCCGCGACACCCGCGGCATGATCCGCCAGCACCAGTTCGACAAGGTGGAGATGGTGCGCGTGG
AGAAGCCGGAACACTCCTACGCCGCGCTGGAGGAAATGGTGGGCCACGCCGAGAACATCCTGAAGGCGCTGGAACTGCCC
TACCGCGTGATCACGCTGTGCACCGGCGACATGGGTTTCGGCTCCGCCAAAACCTACGACCTGGAAGTGTGGCTGCCGGC
GCAGAACACCTACCGCGAGATCTCCAGCTGCTCCAACTGCGAGGCCTTCCAGGCCCGCCGCATGAAGGCGCGCTACAAGG
ACGAAAACGGCAAGAACCAGCTGGTGCACACGCTGAACGGCTCCGGCCTGGCGGTGGGCCGCACCCTGGTGGCCATCCTG
GAAAACTACCAGAACGCCGACGGCAGCGTCACCGTGCCGACCGTGCTGCGCCCCTTCATGGGCAAGGACAGGATAGGCGG
CTGA

Protein sequence :
MLDINLLRNDIEAVAARLAGRGYTLDTAAFNQLESERKSLQSRMQELQAKRNATSKQIGIAKGKGEDVSAILAEVATLGD
ELKAAEQAFDGVQGQLDAWLMSIPNLPHESVPVGKDENDNVEVRRVGVPRQFDFEVKDHVDVGAPLGLDFDTGAKLSGAR
FTVLKGDIARLHRAIAQFMLNTHTGSHGYQEHYTPYIVNDTALLGTGQLPKFADDMFKVTRGGDESAVPQYLISTSEVTL
TNTVADTILQESELPKKMTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVRVEKPEHSYAALEEMVGHAENILKALELP
YRVITLCTGDMGFGSAKTYDLEVWLPAQNTYREISSCSNCEAFQARRMKARYKDENGKNQLVHTLNGSGLAVGRTLVAIL
ENYQNADGSVTVPTVLRPFMGKDRIGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-105 56