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Name : zntA (CV_1154) Accession : NP_900824.1 Strain : Chromobacterium violaceum ATCC 12472 Genome accession: NC_005085 Putative virulence/resistance : Resistance Product : lead,cadmium,zinc and mercury transporting ATPase Function : - COG functional category : P : Inorganic ion transport and metabolism COG ID : COG2217 EC number : - Position : 1212004 - 1214298 bp Length : 2295 bp Strand : + Note : identified by sequence similarity; ORF located using Blastx/COG2217 DNA sequence : CTGGCCCAGGGCGGCGGAGAGCGGCAGACGCGCGAGCATGCCCATGGACGCCAGGGCGGCTGCGGCCACGAACACCAACC GGGCGACCGGCATGGGCACGACCACAAGCATGATCAAGGCCACCAGCATGGCGCGGGTTGCGGCCATTCGCATGGCCATG CGGCGCCGGCCCGGGTGCAACTGGGCGAGGGCAAGGGCGCGAATCTGTCTCGGCTGCAGATCCAGGCGATGGACTGCCCG ACCGAGGCCAGGTTGATCGAGAAGGCGCTTGCCGGCATGGACGGCGTGGTGGCGCTGGAATTCAATTTCATCGAACGGGT GTTGCTGCTGCGCCACGACCTGCCGCACCTGGACGGCGTCAGGAGCGCCATCGCCAAGGTGGGCATGAAGGCGGTGGAGC TGGACGCGGGCGCGCAGGCGCGGGCGCCGCAAGGCCATGGAGGGCGCGCCAACCTGCTGCTGGCGGCGTCAGGCCTGGCC GCCGCCGCGTCGGAGGCCATCGCCTGGAGCCTGGGCGACGGCCGGCTGGAAGTGGCGGCGCTGGCGCTGGCCTCCATCCT GCTGGGCGGCATCCCGACGCTGAAGAAGGGTTGGATCGCGCTGTCCTCCCGCACGCTGAACATCCATTTCCTGATGTCGG TCGCCGTGATCGGCGCGATGCTGATCGGCCAGTGGCCGGAGGCGGCGATGGTGCTGTTCCTGTTCGCCATCGCCGAGCGG CTGGAGGCGATGTCGCTGGCCAAGGCCGGCGAGGCGGTGCGCGCGCTGATGGCGCTGGCGCCGGAAACCGCTTGGGTGGC CGACGGCGCCGGCTGGCGCGAGGCGCAGGCGGCCGAGGTGGCGGTGGGCAGCCGGGTGCGGGTGCGCCCGGGCGAGCGCG TGCCGTTGGATGGCCGCATCGCCGACGGCCACAGCAGCTTCAACGAGGCCAGCATCACCGGCGAGAGCCTGCCGGTGGAC AAGGGGCCCAAGGACGCGGTGTTCGCCGGCAGCATCAACGGCAGCGGCGTGGTGGAGATCGAGACCACGGCGCCGGCGTC CGGCTCGGTGCTGGCGCGCATCATCGCCACCGTGCGCGACGCGCAGGCGTCCAAGGCGCCGACGCAGCGCTTCATCGATC GCTTCGCCTCGGTCTATACCCCGGTGGTGCTGGCCCTGGCGGCCTTGTTCGCCGTGGCCGCGCCGCTGCTGGGCCTGATG GCCTGGCACCAGGCGATCTACAGCGCGTTGGTGATGCTGGTGATCGCCTGCCCGTGCGCGTTGGTGATCGCCACGCCGGT GACCGTGGTCAGCGCGCTGGCCTCGGCCGCGCGCCACGGCCTGCTGGTCAAGGGCGGCGCGCCGCTGGAAATGGCGGCCC GCATCGACACCGTCTGCTTGGACAAGACCGGCACGCTGACCCTGGGCGAGCCGCGCGTCACCCGCGTGGCGGCGCTGGAC GGCGGCGATGAGACCGCGGTGCTGGCGATGGCCGCCGCGTTGGACAGCCATTCCACCCATCCGCTGGCCAAGGCGGTGCT GGACGAGGCCGCGCGGCGCGGCATCGCCGTTCCGGCGGCAGAGCAGGTCAGCGAGCTGGTGGGCCGCGGCGTCCGCGGCC GGGTGGATGGCCGCGCGCTGCAGTTGGGCAGCCGCCGGCTGGCGGAGGAGCAGGGCGCGCTGACGCCGGCGCTGGCGGCT GAGCTGACGCGGATGGACGCCGCGGGCGAGGGGGCGCTGGTGCTGCTGGACGGCGAGCGGGCGCTGGGCGTGCTGGCCGT CGCCGACCAGGTGCGGCCGGAGGCCGCGGCCACCATCGCCCGTCTGGGCGAAATGGGCGTGCGCGCGGTGATGCTCAGCG GCGACAGTCCGCAGGTGGCGGCCGCGGTGGCGGCGCAGACCGGCGTCTCCGCCGCGCACGGCGGCCTGCTGCCGCAGGAC AAGCTGCGCTTCATCGAGCAGCTGCAGGCCTGCGGCAAGGTGGCGATGGTCGGCGACGGCGTCAACGACGCGCCGGCGCT GGCGCGGGCCGACCTGGGCGTCGCGATGGGCGCGGCAGGATCGGACAGCGCGCTGGAGACGGCCGGCGTGGCGCTGATGG ACGACAAGCTGTCGCGGCTGGCCGACCTGATCGTTCACGCCCGCCGCACCGCGTCGGTGCTCAAAGTGAACATCGCGATC GCGTTGGGCATCAAGCTGGTGTTCTTCGGCCTGGCGCTGGCCGGCGTGGCCAGCCTGTGGATGGCGGTGTTCGCCGACGT CGGCACCAGCCTGATCGTGATCGCCAACGGCCTGCGGCTGGCGCGGCGGGTTTAA Protein sequence : MAQGGGERQTREHAHGRQGGCGHEHQPGDRHGHDHKHDQGHQHGAGCGHSHGHAAPARVQLGEGKGANLSRLQIQAMDCP TEARLIEKALAGMDGVVALEFNFIERVLLLRHDLPHLDGVRSAIAKVGMKAVELDAGAQARAPQGHGGRANLLLAASGLA AAASEAIAWSLGDGRLEVAALALASILLGGIPTLKKGWIALSSRTLNIHFLMSVAVIGAMLIGQWPEAAMVLFLFAIAER LEAMSLAKAGEAVRALMALAPETAWVADGAGWREAQAAEVAVGSRVRVRPGERVPLDGRIADGHSSFNEASITGESLPVD KGPKDAVFAGSINGSGVVEIETTAPASGSVLARIIATVRDAQASKAPTQRFIDRFASVYTPVVLALAALFAVAAPLLGLM AWHQAIYSALVMLVIACPCALVIATPVTVVSALASAARHGLLVKGGAPLEMAARIDTVCLDKTGTLTLGEPRVTRVAALD GGDETAVLAMAAALDSHSTHPLAKAVLDEAARRGIAVPAAEQVSELVGRGVRGRVDGRALQLGSRRLAEEQGALTPALAA ELTRMDAAGEGALVLLDGERALGVLAVADQVRPEAAATIARLGEMGVRAVMLSGDSPQVAAAVAAQTGVSAAHGGLLPQD KLRFIEQLQACGKVAMVGDGVNDAPALARADLGVAMGAAGSDSALETAGVALMDDKLSRLADLIVHARRTASVLKVNIAI ALGIKLVFFGLALAGVASLWMAVFADVGTSLIVIANGLRLARRV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ORF C97 | AAN62190.1 | putative metal-transporting P-type ATPase | Not tested | PAGI-2(C) | Protein | 1e-128 | 52 |
| unnamed | BAB47609.1 | cadmium resistance protein B | Not tested | Type-III SCCmec | Protein | 5e-92 | 41 |
| cadA | BAC57487.1 | Probable cadmium-transporting ATPase (Cadmium efflux ATPase) | Not tested | Type-IIIinv SCCmec | Protein | 5e-92 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| zntA | NP_900824.1 | lead,cadmium,zinc and mercury transporting ATPase | BAC0298 | Protein | 2e-130 | 51 |
| zntA | NP_900824.1 | lead,cadmium,zinc and mercury transporting ATPase | BAC0100 | Protein | 8e-57 | 44 |
| zntA | NP_900824.1 | lead,cadmium,zinc and mercury transporting ATPase | BAC0461 | Protein | 2e-84 | 43 |
