Gene Information

Name : thyA (CV_1027)
Accession : NP_900697.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1072637 - 1073431 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCAACAGTACCTCGACCTGATGCGCCATGTGCTGGAACATGGACACGACAAGGCAGACCGCACCGGAACCGGCACCCG
CTCGGTGTTCGGCTACCAGATGCGCTTCGATTTGGCGGCCGGCTTCCCGCTGGTCACCACCAAGAAATGCCATCTGCGCT
CCATCATTCATGAACTGCTGTGGTTCCTGTCGGGCGACACCAATATCCGCTACCTGAAGGAAAACGGCGTGTCGATCTGG
GACGAGTGGGCCGACGAGAACGGCGACCTGGGGCCGGTCTACGGCTACCAGTGGCGCAGCTGGCCGGCGCCGGACGGCCG
CCACATCGACCAGATCAGCCAGCTCTTGGACATGATCAAGAAGAATCCGGACTCGCGCCGGCTGATCGTGTCGGCGTGGA
ATCCGGCGCTGGTGGACCAGATGGCGCTGCCGCCGTGCCACAGCCTGTTTCAGTTCTACGTCGCCAATGGGCGCCTGTCC
TGCCAGCTGTACCAGCGTTCGGCCGACATCTTCCTCGGCGTGCCGTTCAACATCGCCAGCTACGCGTTGCTGACCATGAT
GGTGGCCCAGGTGTGCGGCCTGCAGCCCGGCGATTTCGTCCACACGCTGGGCGACGCCCACCTGTACAGCAACCACCTGG
AGCAGGCCCGGCTGCAACTGACGCGCGATCCCCGCCCGCTGCCGACGATGAAGCTGAACCCGGAGGTGAAGGATCTGTTC
GCGTTCACCTTCGACGACTTCGCGCTGGAAGGCTACGATCCGCATCCGCACATCAAGGCGCAGGTGGCGGTATGA

Protein sequence :
MQQYLDLMRHVLEHGHDKADRTGTGTRSVFGYQMRFDLAAGFPLVTTKKCHLRSIIHELLWFLSGDTNIRYLKENGVSIW
DEWADENGDLGPVYGYQWRSWPAPDGRHIDQISQLLDMIKKNPDSRRLIVSAWNPALVDQMALPPCHSLFQFYVANGRLS
CQLYQRSADIFLGVPFNIASYALLTMMVAQVCGLQPGDFVHTLGDAHLYSNHLEQARLQLTRDPRPLPTMKLNPEVKDLF
AFTFDDFALEGYDPHPHIKAQVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 5e-79 66