Gene Information

Name : pykF (PMM0912)
Accession : NP_893030.1
Strain : Prochlorococcus marinus CCMP1986
Genome accession: NC_005072
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 872358 - 874148 bp
Length : 1791 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGTCGAATATTGATTTAAAAAGGAGAACCAAGATTGTTGCAACAATTGGACCAGCTACTCAATCAGAAGAAATTATTAC
TGATCTTATTAAGGCTGGAGTCACAACATTTCGATTAAATTTTTCTCATGGCGATCATAAAGATCATCAAGAAAGAATAC
AAACCATAAGAAAAGTTTCTGAAAAGCTAGATCTAGATATTGGAATACTTCAGGATCTTCAGGGTCCTAAAATAAGATTA
GGAAGATTTAAAGATGGTCCTGTAAAAGTAAAAAAAGGAGATAAATTCTCATTAACTTCCAATGAAGTTGAATGTACAAA
AAGTATAGCTAATGTTACCTACAACAAACTTGCCCAGGAAGTAACTTCAGGTAAAAGAATATTGTTAGATGATGGAAAAA
TTGAAATGATTGTTGAAAAGGTTGATATAGGAAATAATTTATTAGAGTGTAAAGTAACTGTTGGAGGAGTCCTTTCTAAC
AACAAAGGTGTAAATTTTCCAGATGTACAATTATCTGTTAAAGCTTTAACTGATAAAGATATAGAAGATCTTGAATTTGG
ATTAACTGCTGGTGTTGATTGGATAGCTCTGAGTTTTGTAAGAAATCCGTCTGATATTAATGAAATAAAAAATTTAATAA
ATAAGAATGGACATTCAATTCCTGTTGTAGCCAAGATTGAAAAATTTGAAGCAATAGATCAAATAGATTCAATATTACCT
TTGTGTGATGGGGTTATGGTTGCACGAGGAGACTTAGGAGTTGAAATGCCAGCAGAAGAAGTCCCTCTTTTACAAAAAGA
GTTAATTAGAAAAGCAAATACACTAGGGATCCCCATTATTACCGCCACACAAATGCTTGACTCAATGGCATCAAATCCAA
GGCCAACTCGCGCTGAAGTAAGTGATGTAGCTAATGCAATTCTTGATGGTACAGATGCTGTAATGCTTTCAAATGAAACA
GCTGTGGGTGATTATCCAGTAGAAGCTGTTGAGACCATGGCGACAATTGCTAGAAGAATTGAACGTGATTATCCACTAAA
AGCAATTGAGAGTCACCTTCCTAGTACTATTCCAAATGCAATAAGCGCCGCAGTCAGCAACATTGCTAGACAACTTGATG
CTGGGGCAATAATCCCTTTAACCAAATCCGGTTCAACAGCCCGTAATGTGAGTAAATTCAGACCTCCTACTCCTATTCTT
GCTACCACTACAGAGCGATGTGTCGCGAGAAGATTGCAATTAGTATGGGGAGTGACTCCTTTATTAGTCAAGAATGACGA
TAGGACTGCAAAAACATTCAGTATTGCAATGCAAATAGCACAAGAACTAGGGATTCTTAAGCAAGGAGACCTGGTAGTTC
AGACTGCAGGGACACTAACAGGTATAAGTGGTTCGACTGATCTAATAAAGGTTGGGTTAGTAAGAAAAGTGGTAACTCGA
GGAATATCAGTAGGGGAGATAGGTGTAACTGGCAAAGCAAGAAATATAAAGACTAATCTTGATTTATCATTGATTTCTCC
AGGTGAAATTTTATTTGTACCAAAAAATATCTTAATGGATTTACCTTTCACCAAAATAATTACTGGAATAGTTACGGATG
AAAATATAGATGAATGCTATAAAGTATTCAAAAAAAATAATATTAAGATATCCACTATTTGTAATTTATCTGCTATTGAC
AATCTTGTATCGAACGGGGATTTAATAACGTTACAACTCAATGAAGGGGTTGTTTATATGGGGCAGATAGAAGACGATGA
GGATGCACTAGATAAATATAAGTATGTCTAG

Protein sequence :
MSNIDLKRRTKIVATIGPATQSEEIITDLIKAGVTTFRLNFSHGDHKDHQERIQTIRKVSEKLDLDIGILQDLQGPKIRL
GRFKDGPVKVKKGDKFSLTSNEVECTKSIANVTYNKLAQEVTSGKRILLDDGKIEMIVEKVDIGNNLLECKVTVGGVLSN
NKGVNFPDVQLSVKALTDKDIEDLEFGLTAGVDWIALSFVRNPSDINEIKNLINKNGHSIPVVAKIEKFEAIDQIDSILP
LCDGVMVARGDLGVEMPAEEVPLLQKELIRKANTLGIPIITATQMLDSMASNPRPTRAEVSDVANAILDGTDAVMLSNET
AVGDYPVEAVETMATIARRIERDYPLKAIESHLPSTIPNAISAAVSNIARQLDAGAIIPLTKSGSTARNVSKFRPPTPIL
ATTTERCVARRLQLVWGVTPLLVKNDDRTAKTFSIAMQIAQELGILKQGDLVVQTAGTLTGISGSTDLIKVGLVRKVVTR
GISVGEIGVTGKARNIKTNLDLSLISPGEILFVPKNILMDLPFTKIITGIVTDENIDECYKVFKKNNIKISTICNLSAID
NLVSNGDLITLQLNEGVVYMGQIEDDEDALDKYKYV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-72 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-72 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-72 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-72 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF NP_893030.1 pyruvate kinase VFG0479 Protein 5e-73 44