Gene Information

Name : hemC (PMM0495)
Accession : NP_892613.1
Strain : Prochlorococcus marinus CCMP1986
Genome accession: NC_005072
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 468018 - 468968 bp
Length : 951 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGACTAAATTTAAATTAAAGATAGCTAGTAGAAGAAGTAAATTAGCTATGGTTCAAACATTATGGGTTAAAGAGCAATT
AGAAAAAAATATTCCTGACTTGGAAGTATCGATAGAGGCCATGGCAACTCAAGGTGACAAAATTCTTGATGTCGCCTTAG
CCAAAATAGGAGATAAAGGACTTTTCACAAAAGAACTAGAAGCTCAAATGCTTGTGGGACATGCAGATATTGCAGTGCAT
TCCTTGAAAGATTTGCCTACTAATTTACCTGATGGACTCACATTAGGATGTATTACAAAAAGAGAAGACCCTTCAGATGC
TTTAGTAGTTAACAAAAAAAATAAAATTTATCAATTAGAAAGTTTACCTCCAGGTTCAATCGTTGGAACAAGTTCTTTAA
GGAGACTTGCTCAATTAAGATATAAATTTCCGCATCTTGACTTCAAAGATATTAGGGGTAACGTTATTACAAGAATAGAA
AAACTAGATTCAGGAGAATTTGACTGTATTATTCTAGCTGCAGCGGGTTTAAAAAGATTAGGATTTGAATCAAGAGTTCA
CCAAATTATTCCTAATGAGATTTCCCTTCATGCCGTTGGCCAAGGTGCTTTAGGAATTGAATGTAAATCTGATGATAAAG
AAGTTCTTAAAATTATAAGTGTCCTAGAAGATAAGGTTTCGAGCCAAAGATGTTTAGCAGAAAGATCTTTTTTAAGAGAA
CTTGAAGGGGGATGTCAAGTTCCTATAGGAGTTAATAGTAGTATTCAAAATGATGAAATAGCCCTAATAGGAATGGTCGC
ATCTATCGATGGGAAAAGACTTATTAAAAATGAATCGATAGGAAATATTAAATATCCAGAGGAAGTTGGTAAGAAATTAG
CTGAAAAGCTAAAACTTCAGGGGGCTGATAAAATTCTTTCGGAAATATTTGAACAATTTAGAGATAAGTAA

Protein sequence :
MTKFKLKIASRRSKLAMVQTLWVKEQLEKNIPDLEVSIEAMATQGDKILDVALAKIGDKGLFTKELEAQMLVGHADIAVH
SLKDLPTNLPDGLTLGCITKREDPSDALVVNKKNKIYQLESLPPGSIVGTSSLRRLAQLRYKFPHLDFKDIRGNVITRIE
KLDSGEFDCIILAAAGLKRLGFESRVHQIIPNEISLHAVGQGALGIECKSDDKEVLKIISVLEDKVSSQRCLAERSFLRE
LEGGCQVPIGVNSSIQNDEIALIGMVASIDGKRLIKNESIGNIKYPEEVGKKLAEKLKLQGADKILSEIFEQFRDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-60 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-60 50