Gene Information

Name : leuS (PMT0715)
Accession : NP_894547.1
Strain : Prochlorococcus marinus MIT 9313
Genome accession: NC_005071
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 772530 - 775166 bp
Length : 2637 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGACGGAGTCTTTCCCCTCAACGTCTGCCTCCAGCCAATCCTCAGCTCGATATGACCCTATTGAGCTTGAAACGCGTTG
GCAAAAGGAGTGGTTACGACAAGGATTAGATCGAACGCCAGTCGCAGAAACTAACCAGAAACGCTTTTACGCCCTATCGA
TGTTCCCTTATCCATCAGGGAAACTTCACATGGGCCACGTACGCAATTACGTGATTACCGATGTGATTGCCAGGGTGCAG
CGCATGCGAGGTGATGCGGTACTTCACCCAATGGGATGGGATGCCTTTGGCTTACCAGCTGAGAATGCAGCCATCGCCAG
AAACGTAGATCCAGGTGATTGGACAGACCAAAATATTGCCCAAATGAGGGCCCAGCTTGATCGACTGGGTTTGTCGATTG
ACTGGGACCGGCAACAGGCGACTTGCCATCAGGACTATTACCGCTGGACCCAGTGGTTGTTCCTTGAACTTTTTGCGGGT
GGATTGGCTTATCAGAAGGAAGCGACAGTCAACTGGGATCCCGTCGACAAAACTGTTCTGGCTAATGAACAAGTCGATGG
CGAGGGTCGTTCATGGCGGTCAGGCGCTCTTGTGGAACAGCGACAACTCAAGCAATGGTTCCTGCGAATCACCGACTATG
CCGATGCGTTAATTGATGACCTTGATGAATTGACTGGTTGGCCCGAGCGTGTCCGCACGATGCAAGCCAATTGGATTGGT
CGCTCTCATGGTGCTGAGATCAAGTTCAGAGTCGCTGGTGTAGCCAACTCAATCATCACGGTCTTCACAACAAGGCCAGA
CACACTTCACGGTGCAAGTTATGTGGTTTTGGCACCTGAGCACCCTTTGGTGGAATCCCTAACAAGTCCGGAACAACGTC
TTGCCGTTACTGCATTCTGTGACCTTATAAGCCAACTCAGCGTCAAGGATCGCACCGCTGAGGACCAACCAAAACGTGGG
GTCCCGATCGGTGCACAGGTGATCAATCCAGTCAATGGTGAATCACTACCCGTTTGGATTGCCGATTACGTATTGGCTGA
CTATGGCTCAGGAGCCGTTATGGGAGTACCCGCTCATGATGAGCGGGATTTCATCTTTGCTCGCAGCCACGAACTACCGA
TACGCATTGTGGTGCAGCTGCCAGATACAGACGAGCATCACAATGATGGACAAGCCTGGACCGGGGCCGGAGTTCTTGTA
AATTCTGGAGCCTTTGATGGTCTCTCCACAGAGGAAGCGAAGGTTGCGATTACAACCCATGGAGCTTCTGAGGGTTGGGC
TCAAAGCAAAGTGCAATACCGTTTGCGCGATTGGCTCATTTCTCGTCAGCGCTACTGGGGTTGCCCGATCCCAATCATTC
ACTGTGCAAGCTGTGGAATAGTTCCTGTTCCGCAAGAGGACCTACCTGTAACCCTTCCTAGGGACATAGATCTTTCAGGA
AAAGGAGGATCCCCCATAGCGCAAGAACAGGCTTGGGTTGAGGTTAAATGTCCTATTTGTGGTGAAAAAGCTCACAGGGA
AACAGACACGATGGACACCTTTATGTGTTCTTCATGGTATTACCTACGTTTTGCTGATCCACTCAATAGTCAACGTCCAT
TTGATAAAGATATTGTTGATGAATGGTTGCCTGTTGATCAGTATGTAGGTGGTATTGAACATGCAATCCTCCATCTCCTA
TATGCACGCTTTTTTACAAAAGCACTCCACGATAGAAACCTCATTGGCTTTAAAGAACCATTTAATCGATTACTTACTCA
AGGCATGGTTCAAGGGCTTACCTACCGCAATGCTAAAAATGGCAGTTATATTTCTCCTGAACTTGTTAGTGATGATAGTG
ATCCGAGGGACCCAGAGTCTGGAGACAGACTAGAGGTCCTGTTTGAAAAGATGTCTAAATCAAAATATAATGGCGTTGAT
CCTGCCGTTGTAATCGATCGATACGGTGCCGACACCGCTAGAATGTTCATACTTTTTAAAGCGCCACCAGAGAAAGACCT
GGAATGGGATGATGCAGATGTTGAAGGTCAATTTCGTTTTCTGCAACGACTTATTCGTCTGATTGATAGTTTTGCATGGC
CTAAGACTGATGGTGAGAATGCCTCCATTTCTTCGGCAAACTTGATCATAGATTCAGCTGATCTCAGTGAAGAAGAGATC
AACATGAGAAGAGCTACTCACAAGGCGATAGAGGCAATAACTGAGGACTTAAGTGGTGACATTCAATTGAATACAGCCAT
CTCCGAACTCATGAAGCTATCCAACTCGTTGAGTGGAAAACTAGACAAGGTACGTAATGAAGTGGCTGCAGAGGCTCTTT
CAGTTTTAGTTCGATTGATGGCACCCTTTGCTCCTCATCTTGCAGAAGAATTCTGGCTGAAGCTTCATGGGCATGGAAGC
ATCCATCAACAATCCTGGCCTGTAATCGACCCAAGCGCACTTGTTCTCGAAACGATTGAGCTCGTCATTCAAGTCAAAGG
GAAGGTACGTGGAAAAATCCAGGTACCTGCTAACGCAGACAAAAAGACATTAGAAGAATTGGCCTTAAACAGTGACATCG
CCGTCAAATGGTTAGAAGGTCAATCGCCTAGACGGATCATCATTGTGCCAGGCAAGTTGGTGAACCTAGTGCCATAG

Protein sequence :
MTESFPSTSASSQSSARYDPIELETRWQKEWLRQGLDRTPVAETNQKRFYALSMFPYPSGKLHMGHVRNYVITDVIARVQ
RMRGDAVLHPMGWDAFGLPAENAAIARNVDPGDWTDQNIAQMRAQLDRLGLSIDWDRQQATCHQDYYRWTQWLFLELFAG
GLAYQKEATVNWDPVDKTVLANEQVDGEGRSWRSGALVEQRQLKQWFLRITDYADALIDDLDELTGWPERVRTMQANWIG
RSHGAEIKFRVAGVANSIITVFTTRPDTLHGASYVVLAPEHPLVESLTSPEQRLAVTAFCDLISQLSVKDRTAEDQPKRG
VPIGAQVINPVNGESLPVWIADYVLADYGSGAVMGVPAHDERDFIFARSHELPIRIVVQLPDTDEHHNDGQAWTGAGVLV
NSGAFDGLSTEEAKVAITTHGASEGWAQSKVQYRLRDWLISRQRYWGCPIPIIHCASCGIVPVPQEDLPVTLPRDIDLSG
KGGSPIAQEQAWVEVKCPICGEKAHRETDTMDTFMCSSWYYLRFADPLNSQRPFDKDIVDEWLPVDQYVGGIEHAILHLL
YARFFTKALHDRNLIGFKEPFNRLLTQGMVQGLTYRNAKNGSYISPELVSDDSDPRDPESGDRLEVLFEKMSKSKYNGVD
PAVVIDRYGADTARMFILFKAPPEKDLEWDDADVEGQFRFLQRLIRLIDSFAWPKTDGENASISSANLIIDSADLSEEEI
NMRRATHKAIEAITEDLSGDIQLNTAISELMKLSNSLSGKLDKVRNEVAAEALSVLVRLMAPFAPHLAEEFWLKLHGHGS
IHQQSWPVIDPSALVLETIELVIQVKGKVRGKIQVPANADKKTLEELALNSDIAVKWLEGQSPRRIIIVPGKLVNLVP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-162 43