Gene Information

Name : tktA (PMT1957)
Accession : NP_895782.1
Strain : Prochlorococcus marinus MIT 9313
Genome accession: NC_005071
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2067001 - 2069010 bp
Length : 2010 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGTCGCTGCGACTGCTTCCCTAGACACGCTCTGCATCAACAGCATTCGCATGCTGGCCGTCGATGCGGTCAACAAGGC
CAACAGCGGCCACCCTGGTCTTCCCATGGGCTGTGCCCCCATGGGCTACACCCTCTGGGACCAATTTCTGCATCACAACC
CCAAGAATCCTCAGTGGTTCAACCGCGACCGCTTTGTCCTCTCAGCAGGTCACGGCTGCATGTTGGTTTACGCGCTGTTG
CATCTCACCGGGTATGACTCGGTAAGCATCGAGGACATCAAGCAGTTCCGCCAATGGGGCTCCCGCACTCCTGGACATCC
CGAAACATTTGAAACCCCTGGAGTCGAAGTCACCGCAGGCCCCCTTGGTGCTGGGATCTCTAATGCCGTTGGCCTTGCGA
TCGCTGAAGCTCACCTTGCGGCCAAATTCAATAAACCCGAAGCAAAGATCGTTGATCACTACACCTACGTGGTGATGGGC
GATGGCTGCAACCAAGAAGGTATTGCCTCGGAGGCCTGCTCCCTTGCCGGCCACCTCAAGCTAGGAAAACTGATCGCCCT
CTACGACGACAACCACATCACGATCGACGGCCGCACAGACGTTTCCTTCACCGAAGACGTGCTCAAGCGCTACGAGGCCT
ATGGCTGGCATGTACAACATGTCGCCAATGGCGACACCGACGTGAATGCCATCGCCAAGGCGATCGCTGCCGCCAAGGCC
GTGACCGATAAGCCTTCGATTATCAAGGTGACCACCACCATTGGTTACGGCTCCCCTAACAAAAGCGATACTGCCGGCGT
GCACGGGGCCCCCCTTGGCGAAGAAGAAGCCACTCTCACTCGCCAACAACTGGGATGGAACTATGGCCCTTTTGAAATTC
CCCAAGAGGCCTACGACCAATACCGCAAGGCCATCGATCAAGGCGCTCGCCTTGAATCTGAGTGGAATCAAGCACTCGCC
AACTACAGAAGTCAATACCCAAATGAAGCAGCTGAATTCGAGCGGATGTTGCGCGGTGAGCTTCCCAAGGGGTGGGAAAA
AGATCTACCGACCTATACCCCTGCAGACAGCGGCCTCGCAACGCGTAAGCACTCCCAGATCTGCCTGGGCGCTCTCGGCC
CAAACCTACCGGAACTCATCGGCGGCTCTGCCGACCTCACTCACTCCAATTACACCGATATCAAAGGTGAAACCGGCTCC
TTCCAACCGGAAACACCCGAAAAGCGTTATCTACATTTCGGTGTGCGCGAGCACGCCATGGCCGCCATCCTCAATGGCAT
CGCTTACCACAACAGTGGCCTAATCCCCTACGGCGGAACCTTCCTGGTTTTTGCTGACTACATGCGCGGATCAATGCGCC
TTTCAGCCTTAAGTGAGCTTGGCGTGATCTACGTACTCACCCATGACTCAATCGGCGTCGGTGAAGATGGGCCTACCCAC
CAACCGGTCGAAACCATTCCCTCCCTGCGCGCCATGCCAAACATGCTGGTGTTCCGTCCCGGAGATGGTAATGAGACCAG
CGGAGCGTACAAAGTAGCCATCCAGAATCGCAAACGCCCCAGCTCTCTTTGCCTGAGCCGTCAGGGCATGGCCAACCAAG
CCAATTCATCCATCGAAAATGTCGCTCTCGGCGGCTACGTGCTGGAAGATTGCGAAGGCACAGCTGATCTGATCCTGATC
GGTACAGGCACAGAGCTTGACCTTTGCGTGCAAGCCGCCAAGCAACTCAGTGCTGAAGGCCACAAGATTCGCGTGGTCTC
GATGCCTTGCGTAGAACTTTTCGAAGAGCAGAGCAGCGCATACAAACAAGAGGTGCTGCCAAACGCTGTACGCAAGCGCA
TCGTGGTGGAAGCCGCCGAATCATTTGGCTGGTACAAGTACATCGGCCTTGATGGCGACAGTGTGACCATGAACAGCTTT
GGCGCTTCTGCACCAGGTGGCACATGCATGGAGAAATTTGGCTTCACCGTAGAGAATGTGGTAGCGAAGTCAAAAGCGTT
GCTGAATTGA

Protein sequence :
MVAATASLDTLCINSIRMLAVDAVNKANSGHPGLPMGCAPMGYTLWDQFLHHNPKNPQWFNRDRFVLSAGHGCMLVYALL
HLTGYDSVSIEDIKQFRQWGSRTPGHPETFETPGVEVTAGPLGAGISNAVGLAIAEAHLAAKFNKPEAKIVDHYTYVVMG
DGCNQEGIASEACSLAGHLKLGKLIALYDDNHITIDGRTDVSFTEDVLKRYEAYGWHVQHVANGDTDVNAIAKAIAAAKA
VTDKPSIIKVTTTIGYGSPNKSDTAGVHGAPLGEEEATLTRQQLGWNYGPFEIPQEAYDQYRKAIDQGARLESEWNQALA
NYRSQYPNEAAEFERMLRGELPKGWEKDLPTYTPADSGLATRKHSQICLGALGPNLPELIGGSADLTHSNYTDIKGETGS
FQPETPEKRYLHFGVREHAMAAILNGIAYHNSGLIPYGGTFLVFADYMRGSMRLSALSELGVIYVLTHDSIGVGEDGPTH
QPVETIPSLRAMPNMLVFRPGDGNETSGAYKVAIQNRKRPSSLCLSRQGMANQANSSIENVALGGYVLEDCEGTADLILI
GTGTELDLCVQAAKQLSAEGHKIRVVSMPCVELFEEQSSAYKQEVLPNAVRKRIVVEAAESFGWYKYIGLDGDSVTMNSF
GASAPGGTCMEKFGFTVENVVAKSKALLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 9e-166 53
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-162 52