Gene Information

Name : lysS (PMT0147)
Accession : NP_893980.1
Strain : Prochlorococcus marinus MIT 9313
Genome accession: NC_005071
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 166179 - 167705 bp
Length : 1527 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGCGAGGTCAGTCCTGAGTGCCTTGTCTGAGCTGCGTGAGACTCGCCTGGAAAAGGCACAAGCCCTCAAAGAGCTGGG
GAATGGGCCCTATGCCCTGCGCTTTGAGTCAAGCCATAGCACCGCTAACTTGCAGGCGGATCATGCTGATTTGGCCAAGG
GTGAGGAGAGGCTTCTCACTGTGTCTGTGGCTGGTCGGGTGATGACCCGTCGTGTCATGGGCAAGTTGGCTTTCTATACC
TTGGCGGATGAGACCGGCACGATTCAGTTGTATTTGGAGAAGGCCACCATTGATGCGGCTGCATCAAATGAGCTGGCTTC
AGGAACTTTTGTTCAGCTCACCACCCTTGTTGACGCGGGCGACTGGATTGGGGTCACAGGCGTGCTTCGTCGCACTGACC
GTGGTGAGCTTTCGGTGAAGGTTCAGCAGTGGCAGATCTTGAGCAAATCATTGCAACCCTTGCCAGATAAGTGGCACGGT
TTAGCTGATGTGGAGAAGCGCTATCGGCAACGCTATCTGGATTTGATCGTGTCGCCTCAGTCGCGTGAGACTTTTCGCCG
CCGGGCATTGATGGTGAGTGCAATCCGTCGATGGCTCGATGATCGTGCCTTCTTGGAAATCGAAACACCGGTGCTTCAGG
CTGAGGCCGGTGGCGCCGAAGCTAGGCCATTCATTACTCACCACAACACACTCGATCTTCCTCTTTATCTGCGTATTGCC
ACAGAGCTGCATCTCAAGAGGCTTGTGGTTGGTGGATTTGAGCGGGTCTATGAGCTTGGGCGCATCTTTCGTAACGAGGG
GATGAGTACCCGCCACAACCCTGAATTCACTTCTGTAGAGGTCTATCAGGCCTATGCGGATTACATTGACATGATGGTCC
TTACTGAGCAGCTGATTTCCTCAGTTTGTACTCAGATCTGTGGGTCTACGAGGATCACTTATCAAGGCATAGAAATCGAC
CTAACGCCCCCTTGGCGGAGAGCCAGCATGCACGAACTGGTGCAAGAGGCGACGGGGCTTGATTTCATGGGTTTTAAAGA
CCTTGCGGTAGCGGCTTCGGCTATGGCGCGGGTAGGTCTAGAGGTGCCGTCTAAGGCCGATAGTGTGGGCCGCTTGCTTA
ATGAGGCCTTTGAACAAGCAGTGGAGGTAAGTTTGATCCAGCCAACATTTGTGCTCGACTATCCGATTGAGATCTCGCCT
CTTGCCCGACAACATCGCAGCAAACCAGGATTGGTCGAGCGCTTTGAATTGTTCATTGTGGGTCGGGAAACAGCCAATGC
TTTTAGTGAGTTAATCGATCCCCTTGATCAACGTCAGCGGCTTGAGGCTCAGCAAGCACGCCGTCAGGCTGGGGACCTTG
AGGCTCATGGGGTTGATGAGGATTTCCTTCAGGCTCTTGAGGTGGGCATGCCCCCTACCGGTGGCTTGGGTATTGGCATC
GATCGCTTAGTGATGTTGTTTACCGATAGCCCTTCAATACGTGATGTGATTGCTTTCCCTCTGCTTCGACCGGAGCTCAA
AACTTAA

Protein sequence :
MARSVLSALSELRETRLEKAQALKELGNGPYALRFESSHSTANLQADHADLAKGEERLLTVSVAGRVMTRRVMGKLAFYT
LADETGTIQLYLEKATIDAAASNELASGTFVQLTTLVDAGDWIGVTGVLRRTDRGELSVKVQQWQILSKSLQPLPDKWHG
LADVEKRYRQRYLDLIVSPQSRETFRRRALMVSAIRRWLDDRAFLEIETPVLQAEAGGAEARPFITHHNTLDLPLYLRIA
TELHLKRLVVGGFERVYELGRIFRNEGMSTRHNPEFTSVEVYQAYADYIDMMVLTEQLISSVCTQICGSTRITYQGIEID
LTPPWRRASMHELVQEATGLDFMGFKDLAVAASAMARVGLEVPSKADSVGRLLNEAFEQAVEVSLIQPTFVLDYPIEISP
LARQHRSKPGLVERFELFIVGRETANAFSELIDPLDQRQRLEAQQARRQAGDLEAHGVDEDFLQALEVGMPPTGGLGIGI
DRLVMLFTDSPSIRDVIAFPLLRPELKT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-98 47
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 1e-79 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS NP_893980.1 lysyl-tRNA synthetase VFG1668 Protein 2e-98 47