Gene Information

Name : hemC (PMT1273)
Accession : NP_895101.1
Strain : Prochlorococcus marinus MIT 9313
Genome accession: NC_005071
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1361833 - 1362786 bp
Length : 954 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGGTCCTCACCCAACTGCGCATCGCCTCACGCCGAAGCCAGCTGGCCATGGTGCAAACCAATTGGGTGCAAGCGGAACT
GGAGCAAGCACACCCTGGCCTTTCCATCTCGGTAGAAGCGATGGCAACCCAGGGAGACAAAATTCTCGATGTCGCCCTTG
CCAAGATCGGCGACAAAGGCCTGTTCACGAAAGAGCTTGAAGCTCAGATGCTGGTAGGGCGTGCTGATATAGCTGTTCAT
TCCCTCAAAGATCTACCCACCAATCTTCCCGAAGGGCTCATGCTTGGGTGCGTGACTGAGCGAGAAGACCCAGCCGACGC
TCTGGTAGTGAATCAAAAGAATGCCGAGCATCAACTCGACACCCTGCCTGAAGGGGCAATCGTTGGCACAAGCTCGCTAC
GGCGTCTCGCCCAATTACGGCATCACTACCCCCATCTGGTGTTTAAGGATGTGCGCGGCAATGTGATCACCCGCCTTGAA
AAACTGGATGCCGGCAACTATGACTGCCTGATCCTTGCAGCAGCAGGTCTGACAAGGCTTGGCTTTGGAGATCGCATTCA
TCAGTTGATTCCCAGCGAGATCTCCCTTCATGCCGTTGGCCAGGGAGCCCTAGGCATTGAATGCGTGGAGGGTCACCCCG
AAGTCCTCGAGGCCATCAAGGCACTGGAACACAAACCAACAGCGCAGCGCTGCCTTGCTGAGCGGGCCTTACTAAGAGAA
CTAGAAGGGGGCTGCCAGGTCCCCATCGGTGTCAATAGCCGCATCGAAGCCAACGAATTACTGCTCACAGGCATGGTTGC
CAGCTTGGATGGCAAACGCTTGATACGTGATCAGCAGCGCGGCCCAATTGATCGCTGTGAAGCCATCGGCAAGGAACTCG
CTGAAACGCTGAAATCTCAAGGCGCTGGAGAGATCCTTGCGGAGATCTTCGCTGCTGTCAGGCCAGAAGCCTGA

Protein sequence :
MVLTQLRIASRRSQLAMVQTNWVQAELEQAHPGLSISVEAMATQGDKILDVALAKIGDKGLFTKELEAQMLVGRADIAVH
SLKDLPTNLPEGLMLGCVTEREDPADALVVNQKNAEHQLDTLPEGAIVGTSSLRRLAQLRHHYPHLVFKDVRGNVITRLE
KLDAGNYDCLILAAAGLTRLGFGDRIHQLIPSEISLHAVGQGALGIECVEGHPEVLEAIKALEHKPTAQRCLAERALLRE
LEGGCQVPIGVNSRIEANELLLTGMVASLDGKRLIRDQQRGPIDRCEAIGKELAETLKSQGAGEILAEIFAAVRPEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-55 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-55 50