Gene Information

Name : serRS (SYNW1894)
Accession : NP_897985.1
Strain : Synechococcus sp. WH 8102
Genome accession: NC_005070
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1805643 - 1806920 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGCTCGACCAGCGCCTGGTGCGTGAGAATCCCGATGCCATTGCCACCGAACTGGGGCGTCGGGGCAAAGCCGTTGATCT
CACCCGGCTTCAGGTGATCGCACAGCAGCAGCGCAAGCTGGAGGAAGAGCGCAGTGGACTCCAGGCCGAAGGCAACCGCA
TCGGCAAGGAGGTTGGCCAGAAGATCAAAGGGGGTGCCGACCCCAAAGGTGAAGAGGTCGCTGAACTCAGGCAGCAGGGC
AATGCCATCAAGCAGAAGGTGGCTGTGTTGGAAGAAGAGGAGAAGCACCTCTTCACGCAGCTGAAGGAACAACTCCTCAC
CTATCCCAACCTGCCTTCACCGGACTGTCCTGAGGGAAAGGACGAAACCGACAACGTTGAGCTGCGCCGCTGGGGCAGCC
CAAGACAGGAGGAAGGGCTGGAGGAGCACTGGCAGATCGCCGAACGACTCCACCTATTTGACACCGAGCGATCCGTCCGC
ATCGCCCAGAGCCGTTTTGTCACCTTGATGGGACAGGGCGCCCGATTGGAACGGGCACTGATCAATTTCATGCTGGACCT
GCACACCAGCAAGGGCTACCGGGAAGTGATGCCTCCGGTGCTGGTGAACAGCGCCAGCCTCACGGGATCGGGGCAGCTGC
CCAAATTCGCCGATGACTGTTTCCGTTGCTCGGAGGACGACCTCTGGCTGACCCCCACCGCCGAGGTGCCGGTGACCTCA
CTGCATCGCGACGAGATCATCCCCGCCGATCAGCTGCCGCTCCGCTATGCGGCCTACAGCCCCTGTTTCCGCCGGGAAGC
CGGCAGTTACGGACGGGATACCCGAGGCCTGATCCGTCTGCACCAGTTCAACAAGGTGGAGCTCTACTGGTTCGCCCACC
CGGACCACTCCGCAGAAGCCCACGCTCAGATCACCGCCGATGCCGAAGCCGTTCTTCAGGCACTGGAACTTCCCTACAGG
GTTCTTGATCTCTGCACGGCAGATATCGGCTTCTCAGCGCAACGCACCTACGACCTCGAGGTCTGGTTGCCGGGCGCAGA
GGCTTACCGGGAGATCTCCAGCTGCAGTGTCTGCGGAGATTTCCAGGCCCGGCGTTCTGCCATTCGCACCAAGGAAGGTA
AATCCACCAAACTCGTGCACACTCTCAACGGCAGTGGTCTAGCTGTCGGCCGCACGATGGCGGCTGTGCTGGAAACCGGC
CAGCAATCCGATGGCAGCGTTCTGCTGCCGAAAGCTCTGGTGCCCTACGTCGGCGATGAACGACTCCAGCCAGAATGA

Protein sequence :
MLDQRLVRENPDAIATELGRRGKAVDLTRLQVIAQQQRKLEEERSGLQAEGNRIGKEVGQKIKGGADPKGEEVAELRQQG
NAIKQKVAVLEEEEKHLFTQLKEQLLTYPNLPSPDCPEGKDETDNVELRRWGSPRQEEGLEEHWQIAERLHLFDTERSVR
IAQSRFVTLMGQGARLERALINFMLDLHTSKGYREVMPPVLVNSASLTGSGQLPKFADDCFRCSEDDLWLTPTAEVPVTS
LHRDEIIPADQLPLRYAAYSPCFRREAGSYGRDTRGLIRLHQFNKVELYWFAHPDHSAEAHAQITADAEAVLQALELPYR
VLDLCTADIGFSAQRTYDLEVWLPGAEAYREISSCSVCGDFQARRSAIRTKEGKSTKLVHTLNGSGLAVGRTMAAVLETG
QQSDGSVLLPKALVPYVGDERLQPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-86 49