Gene Information

Name : hemC (SYNW1785)
Accession : NP_897876.1
Strain : Synechococcus sp. WH 8102
Genome accession: NC_005070
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1714571 - 1715524 bp
Length : 954 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGGCTCTCACCGAACTGCGCATCGCCTCACGTCGCAGTCAGCTGGCGATGGTGCAGACCAACTGGGTGAAGGCGGAATT
GGAGAAGGCCCACCCTGGACTCACCATCACGGTGGAGGCGATGGCCACGCAGGGGGACAAGATCCTGGATGTGGCCCTGG
CCAAGATTGGCGACAAGGGCTTATTCACCAAGGAACTGGAAGCGCAGATGCTGGTGGGACGCGCGGAGATCGCCGTCCAT
TCTCTGAAGGATCTGCCCACCAACCTGCCTGAAGGCCTGATGCTGGGCTGCATCACTGAACGGGAAGATCCAGCTGATGC
TCTGGTGGTGAATGCGAAAAATGCCAACCACAAACTCGACACCCTGCCGGAGGGTGCCGTGGTGGGCACCAGCTCCCTGC
GCCGGCTGGCCCAGCTGCGGCATCACTACCCACATCTGAGCTTCAAGGACGTTCGCGGCAACGTGATCACGCGCCTGGAG
AAGCTCGACTCAGGCGATTACGACTGCTTGATCCTGGCGGCAGCAGGCTTGGAGCGCCTGGGATTCGGCAACCGGATCCA
CCAGATCATCCCGGGTGACATCTCTCTTCATGCCGTTGGCCAGGGCGCCCTCGGCATCGAATGCGTGGAAGACAAGCCAG
AGGTTCTGGAAATCATCAAGGTGCTGGAGCACACCACCACCTCACGCCGCTGTCTGGCGGAACGCGCCTTCCTGCGAGAG
CTGGAGGGGGGCTGCCAGGTGCCGATCGGTGTCAACAGCCAGATCAACAATGAAGAACTCACCCTCACGGGCATGGTGGC
CAGCCTGGATGGCAAGCGCCTGATCCGCGATGAGGCCAGTGGTTCCGCTGCTGACCCCGAGTCCATTGGCATCGAGCTGG
CTGGCAAACTCAAGCACCAGGGTGCGGGAGCCATCCTCAAGGAAATCTTTGATGAGGTCCGTCCTGAGGCCTGA

Protein sequence : 
MALTELRIASRRSQLAMVQTNWVKAELEKAHPGLTITVEAMATQGDKILDVALAKIGDKGLFTKELEAQMLVGRAEIAVH
SLKDLPTNLPEGLMLGCITEREDPADALVVNAKNANHKLDTLPEGAVVGTSSLRRLAQLRHHYPHLSFKDVRGNVITRLE
KLDSGDYDCLILAAAGLERLGFGNRIHQIIPGDISLHAVGQGALGIECVEDKPEVLEIIKVLEHTTTSRRCLAERAFLRE
LEGGCQVPIGVNSQINNEELTLTGMVASLDGKRLIRDEASGSAADPESIGIELAGKLKHQGAGAILKEIFDEVRPEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-64 52
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-64 52