Gene Information

Name : tktA (SYNW0141)
Accession : NP_896236.1
Strain : Synechococcus sp. WH 8102
Genome accession: NC_005070
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 136580 - 138589 bp
Length : 2010 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGTCGCTGCGCCCGCGTCTCTCGACACGCTCTGCATCAACAGCATCCGGATGCTGGCCGTCGATGCCATCAACAAGTC
CAAGAGCGGCCACCCCGGCCTGCCGATGGGCTGCGCACCCATGGGTTACGCGCTGTGGGACAAGTTCCTGAAGCACAACC
CCAAGAACCCCAAGTGGTTCAACCGCGACCGCTTTGTGCTGTCGGCTGGTCACGGCTGCATGCTGCTGTACGCGCTGCTG
CACCTCACCGGCTACGACTCGGTGTCGATCGACGACATCAAGCAGTTCCGTCAGTGGGGCTCCAAGACGCCCGGCCACCC
CGAAACCTTTGAAACTCCTGGCGTGGAAGTGACCACCGGCCCCCTGGGCGCTGGCATCTCCAACGCCGTGGGTCTGGCGA
TCGCTGAATCCCACCTGGCCGCCAAGTTCAACAAGCCCGGCGCCACCCTCGTGGATCACTACACCTATGTGGTGATGGGT
GATGGCTGCAACCAGGAGGGCATCGCTTCGGAAGCCTGCTCCCTGGCCGGCCACCTGAAACTGGGCAAGCTGATCGCCTT
CTACGACGACAACCACATCACCATCGACGGCCGCACGGACGTGTCCTTCACCGAGGACGTGCTCAAGCGCTACGAGGCCT
ACGGCTGGCATGTGCAGCACGTGGCCGACGGCAACACCGATGTGGACGCCATCGCCAAGGCGATCGAAGCCGCCAAGGCC
GTGACCGACAAGCCGTCGATCATCAAGGTGACCACCACCATCGGCTACGGCTCCCCCAACAAGGGCGACACCGCCGGCGT
GCACGGTGCACCCCTGGGTGAAGACGAAACCGTTCTCACCCGCCAGCAGCTGGGCTGGGAGTACGGCCCCTTCGAGGTGC
CCCAGGAGGCTTACGACCAGTTCCGTCAGGCGATCGAGCGTGGCGCCAGCCTCGAAGCCGAGTGGAACCAGACCCTGGCC
ACCTATCGCACCCAATTCCCCGCTGAAGCGGCTGAGTTCGAGCGGATGCTCCGCGGTGAACTGCCCGAGGGATGGGACAA
GGATCTGCCCACCGCTGGCCCTGACGAGAAGGGTCTGGCCACCCGCAAGCACTCCCAGATCTGCCTGGGTGCCCTCGGCC
CCAACCTGCCCGAACTGATCGGCGGCTCGGCTGACCTCACCCACTCCAATTACACCGATATCAAGGGTGAGACCGGCTCC
TACCAGCCTGAAACCCCTGAGAAGCGTTACCTGCACTTCGGCGTGCGTGAGCACGCCATGGCGGCCATCCTCAACGGCAT
CGCATATCACGACAGCGGCCTGATCCCCTACGGCGGCACCTTCTTGGTGTTCGCCGACTACATGCGCGGCTCGATGCGCC
TGTCGGCCCTGAGCGAGCTGGGTGTGATCTACGTGCTTACCCACGACTCCATCGGCGTCGGTGAAGACGGCCCCACCCAC
CAGCCGATCGAGACCATCCCCTCCCTGCGCGCTATGCCCGGGATGCTGGTGTTCCGTCCTGGCGATGCCAACGAGACCAG
CGGCGCCTACAAGCTGGCGATTCAAAACCGCAAGCGCCCCAGCGCTCTCTGCCTCAGCCGCCAGGGCATGGCCAACCAGG
CCAACTCCTCGATCGACAAGGTCGCCAAAGGTGGTTACGTGCTGGAGGATTGCGACGGCACCCCTGAGCTGATCCTGATC
GGCACCGGCACCGAGCTCGACCTCTGCGTCCAGGCTGCCAAGCAACTGACGGAAGCCGGCAAAAAGGTTCGCGTGGTGTC
CATGCCATGCGTAGAGCTGTTCGACGAGCAGAGCGACGCCTACAAAGAAAAGGTGCTCCCCAACGCCGTACGAAAGCGCA
TGGTGGTGGAAGCCGCTGAATCCTTCGGCTGGCACCGCTTCATCGGCCTCGACGGCGACAGCGTGACCATGAACCGCTTT
GGTGCTTCCGCCCCCGGTGGCACCTGTCTGAAGGAGTTCGGTTTCACCGTGGAGAACTTGGTGGCCAAGGCCAGCGCCCT
ATTGGCCTGA

Protein sequence :
MVAAPASLDTLCINSIRMLAVDAINKSKSGHPGLPMGCAPMGYALWDKFLKHNPKNPKWFNRDRFVLSAGHGCMLLYALL
HLTGYDSVSIDDIKQFRQWGSKTPGHPETFETPGVEVTTGPLGAGISNAVGLAIAESHLAAKFNKPGATLVDHYTYVVMG
DGCNQEGIASEACSLAGHLKLGKLIAFYDDNHITIDGRTDVSFTEDVLKRYEAYGWHVQHVADGNTDVDAIAKAIEAAKA
VTDKPSIIKVTTTIGYGSPNKGDTAGVHGAPLGEDETVLTRQQLGWEYGPFEVPQEAYDQFRQAIERGASLEAEWNQTLA
TYRTQFPAEAAEFERMLRGELPEGWDKDLPTAGPDEKGLATRKHSQICLGALGPNLPELIGGSADLTHSNYTDIKGETGS
YQPETPEKRYLHFGVREHAMAAILNGIAYHDSGLIPYGGTFLVFADYMRGSMRLSALSELGVIYVLTHDSIGVGEDGPTH
QPIETIPSLRAMPGMLVFRPGDANETSGAYKLAIQNRKRPSALCLSRQGMANQANSSIDKVAKGGYVLEDCDGTPELILI
GTGTELDLCVQAAKQLTEAGKKVRVVSMPCVELFDEQSDAYKEKVLPNAVRKRMVVEAAESFGWHRFIGLDGDSVTMNRF
GASAPGGTCLKEFGFTVENLVAKASALLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-165 53
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-162 53