Gene Information

Name : pykF (SYNW1298)
Accession : NP_897391.1
Strain : Synechococcus sp. WH 8102
Genome accession: NC_005070
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1294576 - 1296030 bp
Length : 1455 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGGGCCAGTTCGATCAGAACCGTCGGACCAAGATCGTGGCCACCATCGGTCCAGCCACGGAAAGTTCCGAGCGAATCAA
GGAACTGGTTCAGGCTGGAGCCACCACCTTTCGGTTGAATTTCTCCCACGGCGACCACAGCGAGCATGCGGCGCGGATTT
CGACCATCCGCCAGGTGTCTGAAGAGCTCGGGATCAACATCGGCATCCTTCAAGACCTGCAGGGACCAAAAATCCGCCTG
GGCCGTTTTGCTGAGGGACCGATCACCCTTGCCAATGGCGACAGCTTCTCCCTGACGTCCAGGCCGGTGAGTTGCAACCA
ATCCATCGCCACCGTCACCTACGACAAACTCGCTGACGAAGTCACCGCAGGAAGCCGCATCCTTCTCGACGACGGCCGCG
TTGAGATGAAAGTCGAGCAGGTGGATCAGGCTGAACAGACCCTGCACTGCACCGTCACCGTTGGCGGTGTTCTCTCCAAC
AACAAAGGAGTGAACTTCCCCGACGTGCAGCTGTCCGTCCGCGCTCTGACGGACAAGGACAAGGTGGATCTGGAATTCGG
TCTCTCCCAGGGGGTCGACTGGGTGGCCCTGAGCTTCGTACGCAACCCCTCCGACATGGAGGAAATCCGTGGTCTGATCC
GTGAGCATGGCCACGAGACCCCCGTCGTCGCCAAGATTGAGAAGTTTGAGGCCATCGACCAGATCGATGCCATCCTTCCC
CTGTGCGATGGCGTGATGGTCGCCAGGGGTGACCTGGGGGTAGAGATGCCCGCTGAGGAGGTTCCTCTTCTGCAGAAGGA
ATTGATCCGGAAAGCCAACAGCCTGGGCATTCCGATCATCACGGCCACCCAGATGCTGGATTCGATGGCCTCCAGCCCGC
GACCCACCCGCGCTGAAGTGAGCGATGTGGCCAACGCCATTTTGGATGGCACCGATGCAGTGATGCTCTCCAACGAAACG
GCCGTCGGCGATTTCCCGGTGGAAGCCGTTCAAACGATGGCGACCATCGCCTGCCGGATCGAAAAGGATTATCCCCAGCG
TTCCGTTGACAGCCATCTGGCCAGCACGGTGCCGAATGCCCTGAGTGGCGCCGTCAGCACCATCGCCAGTCAGCTGAACG
CCTCGGCGATCCTTCCTCTCACCAAAAGCGGAGCGACGGCTAAGAACGTCAGCAAGTTCCGTCCCGCATCGCCGATTCTG
GCCATTACCCCTGATCCAACCGTGGCCTGCCGTCTGCAACTGGTTTGGGGAGTGAAGCCGCTGGTGATCCCGCAGCACGA
ACTCACCACTCACACGTTCCTTGCCGCGATGACCCAGGCCAAAACAATGGGGCTTCTGAAGGAAGGTGATCTGGTCGTTC
AGACGGCCGGGACCCACACGGGTGTCTCCGGTTCCACCGATCTGGTCAAGGTGGGCATCGTCAGTTCAGAGGAAGCACCC
GTCAACATGATCTGA

Protein sequence :
MGQFDQNRRTKIVATIGPATESSERIKELVQAGATTFRLNFSHGDHSEHAARISTIRQVSEELGINIGILQDLQGPKIRL
GRFAEGPITLANGDSFSLTSRPVSCNQSIATVTYDKLADEVTAGSRILLDDGRVEMKVEQVDQAEQTLHCTVTVGGVLSN
NKGVNFPDVQLSVRALTDKDKVDLEFGLSQGVDWVALSFVRNPSDMEEIRGLIREHGHETPVVAKIEKFEAIDQIDAILP
LCDGVMVARGDLGVEMPAEEVPLLQKELIRKANSLGIPIITATQMLDSMASSPRPTRAEVSDVANAILDGTDAVMLSNET
AVGDFPVEAVQTMATIACRIEKDYPQRSVDSHLASTVPNALSGAVSTIASQLNASAILPLTKSGATAKNVSKFRPASPIL
AITPDPTVACRLQLVWGVKPLVIPQHELTTHTFLAAMTQAKTMGLLKEGDLVVQTAGTHTGVSGSTDLVKVGIVSSEEAP
VNMI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-75 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-75 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-75 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-75 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF NP_897391.1 pyruvate kinase VFG0479 Protein 7e-76 44