Gene Information

Name : lysS (SYNW0127)
Accession : NP_896222.1
Strain : Synechococcus sp. WH 8102
Genome accession: NC_005070
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 124707 - 126215 bp
Length : 1509 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGTCTGAGCTGCGCGACACCCGTTTGGAGAAGTGCCAGGCACTGTCTGATCTGGGCCAGGGTCCCTACGCCCTCAACTT
TGAGCCGACCCATCGCATGGCGGCCTTGCATGAGGCCCATGCCGACCTCCCCAATGGCGAGGAACGTGAGGTGACGGTGT
CCGTCGCCGGGCGGGTGATGACCCGGCGGGTGATGGGCAAGCTCGCCTTTTTCACCCTGGCGGATGAGACCGGCACCATT
CAGCTGTTTCTGGAGAAAGCGGGCCTGGAGGCGCAGCAGGAGGGCTGGTTCAAGCAGATCACCGGTCTGGTCGATGGCGG
CGACTGGCTTGGGGTGAGCGGCACGCTGCGCCGCACCGATCGCGGTGAGTTGTCGGTGAAGGTGAGCGATTGGCGCATGC
TCACCAAGGCGCTGCAACCGCTGCCGGATAAGTGGCACGGCCTGGCCGATGTGGAGAAGCGCTACCGCCAGCGCTATCTC
GACCTCATCGTGTCGCCGGACAGCCGGGAGACTTTCCGCCGCCGGGCACGGTTGGTGAGCGGCATCCGCCGCTGGCTGGA
TCAACGTGATTTTCTCGAAATTGAGACTCCGGTGCTGCAGAGCGAACCGGGCGGTGCCGATGCTCGGCCCTTCGAGACCC
ACCACAACGCTCTTGATCTTCCCCTCACCCTGCGCATCGCCACCGAACTGCATCTCAAACGCCTGGTGGTGGGTGGCTTC
GAGCGGGTGTACGAGCTGGGCCGGATCTTTCGCAATGAAGGGGTCAGCACCCGCCACAACCCGGAATTCACCTCGGTGGA
GATCTATCAGGCCTACTCCGATTACATCGGAATGATGGAGCTCACTGAGCAGATGGTCAGCGCCGTTTGCCAGGAGGTGT
GCGGCAGTTGCCAGATCACGTACCAGGACACCGAGATTGATCTCAGCCCCCCCTGGCGACGGGCCACCATGCATGAGCTA
GTGGAGGAAGCCACCGGTCTTGATTTCAATAGCTTCAGCAGTCGGGAGGCGGCGGCTGTAGCGATGACCGGCAAGGGCCT
GCATGCACCTGAACTGGCCGATTCCGTGGGGCGTCTGCTGAATGAAGCGTTCGAGCAGGCGGTGGAGACAACGCTGATTC
AACCCACCTTTGTGACCGATTACCCGGTGGAGATTTCACCGTTGGCCCGGCCTCACCGCAGCAAACCCGGCCTGGTGGAA
CGTTTTGAGCTGTTCATCGTTGGCCGCGAGCATGCCAATGCCTTCAGTGAGCTCACCGATCCGGTGGATCAGCGGCAGCG
CCTGGAGGCCCAGCAGGCCCGTAAGGCTGCCGGGGATCTCGAAGCGCAGGGGTTGGATGAAGACTTCGTCACGGCCCTCG
AGGTGGGCATGCCTCCCACCGGTGGGTTGGGTATTGGTATCGATCGTTTGGTGATGCTGCTCACGGATAGCCCATCGATC
CGTGATGTCATTGCCTTCCCGCTTCTGCGGCCGGAGCCCAGGGCGGCGGATGCCCCCGCAATGGGATAA

Protein sequence :
MSELRDTRLEKCQALSDLGQGPYALNFEPTHRMAALHEAHADLPNGEEREVTVSVAGRVMTRRVMGKLAFFTLADETGTI
QLFLEKAGLEAQQEGWFKQITGLVDGGDWLGVSGTLRRTDRGELSVKVSDWRMLTKALQPLPDKWHGLADVEKRYRQRYL
DLIVSPDSRETFRRRARLVSGIRRWLDQRDFLEIETPVLQSEPGGADARPFETHHNALDLPLTLRIATELHLKRLVVGGF
ERVYELGRIFRNEGVSTRHNPEFTSVEIYQAYSDYIGMMELTEQMVSAVCQEVCGSCQITYQDTEIDLSPPWRRATMHEL
VEEATGLDFNSFSSREAAAVAMTGKGLHAPELADSVGRLLNEAFEQAVETTLIQPTFVTDYPVEISPLARPHRSKPGLVE
RFELFIVGREHANAFSELTDPVDQRQRLEAQQARKAAGDLEAQGLDEDFVTALEVGMPPTGGLGIGIDRLVMLLTDSPSI
RDVIAFPLLRPEPRAADAPAMG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-104 48
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 3e-80 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS NP_896222.1 lysyl-tRNA synthetase VFG1668 Protein 3e-104 48