Gene Information

Name : leuS (SYNW1255)
Accession : NP_897348.1
Strain : Synechococcus sp. WH 8102
Genome accession: NC_005070
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1249942 - 1252515 bp
Length : 2574 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGAACAGCCGTTACTCGCCTGCGGACCTTGAACAACGCTGGCAGACGACCTGGCGATCAGAGGGGTTGGATGTCACTCC
GGAGCCTGAAGACGGAAAGGGTTTCTACGCCCTGTCGATGTTTCCCTACCCCTCAGGGACCTTGCACATGGGCCATGTGC
GCAATTACGTCATCACCGATGTGATCGCCCGCGTTCAACGGATGCGTGGCCACTCGGTGTTGCACCCGATGGGATGGGAT
GCCTTCGGTCTTCCCGCCGAAAATGCCGCGATAGAACGCAACGTTGATCCCGGCGATTGGACCGATCGCAACATCGATCA
GATGCGATCGCAGCTGGATCGCCTCGGCTTGTCGATCGACTGGGACCGTGAGCAGGCCACCTGCCACAGCGATTACTACC
GATGGACCCAGTGGTTGTTCCTGGAGCTCTTCGATGGCGGTCTGGCCTACCGGAAGAACGCAACGGTCAACTGGGATCCA
GTCGATCAAACCGTTCTTGCCAACGAGCAGGTCGATGCCGACGGACGTTCCTGGCGATCCGGTGCACTGGTGGAACAGCG
ACAGTTAAATCAGTGGTTCCTGCGGATCACGCAGTACGCCGAAGCCCTGCTCAATGACCTCGATCAGCTGAGCGGATGGC
CTGAGCGCGTTCGCACGATGCAGGCCAACTGGATCGGTCGTTCCGAGGGTGCTGAGATCCAGTTCAAGGTGTCCTCCGAT
TCCGACACAACCATCACAGTGTTCACCACAAGGCCAGACACCTTGGCTGGTGCCAGCTGCGTGGTGCTCGCCCCGGACCA
CCCGTTGGTGAACAGCCTGACGAGCCCGGATCAGCAGGATGTTGTGCAGGCCTTCCAGGCAGAGGTGGCTCGCCTCAGTG
CCTTGGAGCGCACCAGTGATGACGCTCCCAAGCGTGGAGTCTTCACTGGCGCCACCGTCCTCAATCCACTCAACGGCAGG
GCATTGCCGGTGTGGATCGCGGACTATGTGCTGGTGGATTACGGCACCGGCGCCGTGATGGGAGTCCCCGCCCATGACCA
GCGGGACCGACGCTTTGCGCAGAGCTACGGGCTGGCCGTTCAGCAAGTGATTGAGGCCGAGGGGGCCGCCGCTGCGATCG
CGGCCGGAGAGGCCTGGACGGATCCTGGAGTGCTGATTCATTCAGGAGACTTCGATGGTCTGAATTCCATCGAGGCCAAG
GAGCGGATCACGCGCCACGGGGAGCAGCAGGGATGGGCAGTAGCGAAGGTCACCTATCGGCTGCGCGATTGGCTGATTTC
AAGACAGCGCTACTGGGGCTGCCCGATTCCGATCATCCATTGCCCTAGCTGCGGTGCCGTTCCCGTGCCTCGCGAGGACC
TACCCGTGGTACTCCCACGCGGCATTGATCTGTCAGGGAAAGGAGGCTCACCACTTGAGCAGCAGCAGGATTGGGTCAAC
GTCCCCTGTCCCTCCTGTGGCGAACCGGCCAAACGCGAAACCGACACGATGGACACCTTCATGTGTTCGTCCTGGTATTT
CCTCCGTTTCGCGGATCCACACAACACGGAACAGCCGTTCAGCCGTGAAGCCGTGAATCGCTGGCTGCCGGTGCAGCAGT
ACGTCGGCGGCATTGAGCACGCCATTTTGCATCTGCTGTATTCCCGCTTTTTCACCAAGGCGTTGAAGGATCGGGGCTTG
ATCGATGTGGCTGAACCATTTGATCGTCTGCTGACCCAGGGAATGGTTCAGGGAACGACATATCGCAATCCCAGCACCGG
CAAATACGTCGCCTCTGCGGATGTGTCGGACCCGGAGACACCGACCGATCCGACCAGCGGTGAACCTCTGGAGGTGTTAT
TCGAAAAGATGTCGAAGTCGAAGTACAACGGCGTCGACCCTGCGGCAGTGATCGATCGCTACGGCGCCGACACCGCTCGC
ATGTTCATTTTGTTCAAGGCACCGCCCGAGAAGGACCTCGAATGGGATGACTCTGACGTGGAAGGTCAATTCCGCTTCCT
GCAGCGGATCTGGCGGCTGGTGGAGTCCGCCGACTCCCGTATCGACAGCCTCGAGCCAGAGGAGCGTCCCGAGCCGTTGG
CCGACACCGACGCCAAGGTTCGTCGTGCCATCCACATCGCCATCGATGCGGTGAGTGAGGACCTGCAGGACGAGATTCAG
TTGAACACCGCCATCTCGGAGCTGATGAAGCTCACCAATGCGATCACTTCCGTTGGTGTTGCGGAGTTGAGCACGTCAGT
GCTGAAGGAAGCCCTCTCAACACTGCTTCGGCTTCTGGCACCCTTTGCTCCCCATCTTGCCGAAGAGCTTTGGCATCAGC
TCGGGGGTACGTCCAGCGTGCATCGTGCCGGTTGGCCAGAACTGGACCCCAGTGCTTTGGTTCAGGATTCCGTGGACCTG
GTGATTCAGATCAAGGGGAAGGTTCGGGGGACCATTCAGGTTCCCGCCGCCGCCGACAAAGAACAGCTTGAGGCCTTGGC
ACTGGCCAGTGAGATCGCTGCCAAATGGCTGGAGGGACACCCCCCCCGACGCGTGATTGTGGTGCCGGGGAAGTTGGTCA
ACCTGGTGCCCTGA

Protein sequence :
MNSRYSPADLEQRWQTTWRSEGLDVTPEPEDGKGFYALSMFPYPSGTLHMGHVRNYVITDVIARVQRMRGHSVLHPMGWD
AFGLPAENAAIERNVDPGDWTDRNIDQMRSQLDRLGLSIDWDREQATCHSDYYRWTQWLFLELFDGGLAYRKNATVNWDP
VDQTVLANEQVDADGRSWRSGALVEQRQLNQWFLRITQYAEALLNDLDQLSGWPERVRTMQANWIGRSEGAEIQFKVSSD
SDTTITVFTTRPDTLAGASCVVLAPDHPLVNSLTSPDQQDVVQAFQAEVARLSALERTSDDAPKRGVFTGATVLNPLNGR
ALPVWIADYVLVDYGTGAVMGVPAHDQRDRRFAQSYGLAVQQVIEAEGAAAAIAAGEAWTDPGVLIHSGDFDGLNSIEAK
ERITRHGEQQGWAVAKVTYRLRDWLISRQRYWGCPIPIIHCPSCGAVPVPREDLPVVLPRGIDLSGKGGSPLEQQQDWVN
VPCPSCGEPAKRETDTMDTFMCSSWYFLRFADPHNTEQPFSREAVNRWLPVQQYVGGIEHAILHLLYSRFFTKALKDRGL
IDVAEPFDRLLTQGMVQGTTYRNPSTGKYVASADVSDPETPTDPTSGEPLEVLFEKMSKSKYNGVDPAAVIDRYGADTAR
MFILFKAPPEKDLEWDDSDVEGQFRFLQRIWRLVESADSRIDSLEPEERPEPLADTDAKVRRAIHIAIDAVSEDLQDEIQ
LNTAISELMKLTNAITSVGVAELSTSVLKEALSTLLRLLAPFAPHLAEELWHQLGGTSSVHRAGWPELDPSALVQDSVDL
VIQIKGKVRGTIQVPAAADKEQLEALALASEIAAKWLEGHPPRRVIVVPGKLVNLVP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-164 44