Gene Information

Name : smpB (CpB0345)
Accession : NP_876622.1
Strain : Chlamydophila pneumoniae TW-183
Genome accession: NC_005043
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 378986 - 379483 bp
Length : 498 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
TTGTTATACTGGTTTTTGTCCCCAATTATGGGGGAGGATCTTATGGCACAAAAAGAAATTGTTTCTAATCGCAAGGCTCT
GCGTAACTATGAAGTTATAGAGACTTTAGAAGCAGGCATCGTTTTGACTGGGACTGAGATTAAGTCGTTGCGCGATCATG
GGGGAAACCTCGGTGATGCTTATGTCATTGTTTCTAAAGGTGAGGGGTGGTTATTAAACGCGAGTATTGCTCCCTATCGG
TTTGGAAATATCTATAACCATGAGGAGCGTCGTAAACGTAAACTCCTTCTTCATAGATATGAACTTCGTAAGTTAGAGGG
TAAGATTGCTCAAAAGGGCATGACTTTGATTCCTCTGGGAATGTTGCTGAGTCGCGGCTATGTTAAGGTACGTTTGGGTT
GTTGTCGTGGGAAAAAAGCTTATGATAAGCGTCGTACGATCATAGAAAGAGAAAAGGAACGTGAAGTTGCCGCTGCTATG
AAGAGGCGCCATCATTGA

Protein sequence :
MLYWFLSPIMGEDLMAQKEIVSNRKALRNYEVIETLEAGIVLTGTEIKSLRDHGGNLGDAYVIVSKGEGWLLNASIAPYR
FGNIYNHEERRKRKLLLHRYELRKLEGKIAQKGMTLIPLGMLLSRGYVKVRLGCCRGKKAYDKRRTIIEREKEREVAAAM
KRRHH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-13 49
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 8e-12 45