Gene Information

Name : CpB0145 (CpB0145)
Accession : NP_876421.1
Strain : Chlamydophila pneumoniae TW-183
Genome accession: NC_005043
Putative virulence/resistance : Virulence
Product : ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 175449 - 178058 bp
Length : 2610 bp
Strand : +
Note : heat shock protein; similar to heat shock protein ClpB - Synechococcus sp.

DNA sequence :
GTGAATTTTATGGAGAAATTTTCCGATGCTGTCTCTGAAGCTTTAGAGAAGGCTTTCGAACTTGCTAAATCTTCGAAACA
TACCTATGTCACAGAAAATCACCTATTACTGGCTTTATTAGAAAATACAGAGTCTCTCTTTTATTTGGTAATTAAGGACA
TTCATGGGAACCCTGGTTTGCTCAATACGGCAGTTAAAGATGCGCTCTCACGAGAGCCGACTGTAGTTGAAGGAGAGGTG
GATCCTAAACCTTCTCCGGGTTTACAAACCCTTCTTAGGGATGCCAAACAAGAGGCAAAGACATTAGGAGATGAATACAT
TTCTGGAGATCATCTGCTGCTTGCTTTTTGGAGTTCAAACAAAGAGCCTTTTAATTCTTGGAAGCAAACAACAAAAGTTA
GTTTTAAAGATCTTAAGAATCTGATTACTAAAATACGACGAGGAAATCGTATGGATTCGCCAAGCGCTGAAAGTAATTTT
CAGGGTTTAGAAAAGTATTGTAAAAATTTAACAGCATTAGCTCGTGAAGGTAAACTGGATCCTGTGATCGGTAGAGATGA
AGAAATTCGTAGAACCATCCAAGTGCTTTCCCGTAGAACTAAAAATAACCCTATGCTTATTGGTGAGCCGGGTGTAGGGA
AAACTGCTATAGCAGAAGGATTAGCTCTTAGGCTTATCCAGGGTGATGTTCCTGAATCTCTCAAAGGTAAACAGCTTTAT
GTCTTAGATATGGGAGCTTTGATTGCAGGAGCTAAGTATCGAGGTGAGTTTGAAGAAAGACTAAAGAGTGTTTTAAAAGA
TGTAGAATCTGGAGATGGCGAGCACATTATCTTTATTGATGAGGTGCATACTCTTGTTGGAGCAGGAGCTACTGATGGAG
CTATGGATGCTGCGAATCTTTTAAAGCCTGCATTAGCAAGAGGGACGCTACACTGTATTGGCGCGACGACTTTGAATGAG
TATCAGAAGTATATTGAAAAAGATGCTGCTTTGGAACGTCGATTTCAGCCTATTTTTGTGACAGAGCCTTCTTTGGAGGA
TGCTGTCTTTATTCTTCGTGGACTAAGAGAAAAATATGAAATTTTCCATGGAGTCAGGATTACAGAGGGGGCTTTGAATG
CCGCAGTCCTACTTTCCTATCGTTATATCCCAGATCGCTTTCTTCCAGATAAGGCTATCGATTTGATAGATGAAGCGGCA
AGTTTAATTCGCATGCAAATTGGTAGTCTTCCTCTTCCTATTGATGAAAAGGAGAGAGAGCTTGCTGCTTTGATCGTTAA
GCAAGAGGCTATAAAACGCGAGCAATCTCCTTCCTATCAAGAAGAGGCGGATGCTATGCAGAAGTCTATAGATGCTTTGA
GAGAGGAATTAGCATCTCTACGTTTGGGTTGGGATGAAGAGAAGAAGTTGATTTCGGGGCTCAAGGAAAAAAAGAATTCC
TTGGAAAGTATGAAATTTTCTGAAGAGGAGGCGGAGCGTGTTGCAGACTATAATCGTGTAGCTGAGCTTCGGTATAGTTT
AATTCCCCAACTTGAAGAAGAAATCAAACAGGATGAAGCCTCTTTAAATCAAAGAGATAACCGTCTCCTTCAAGAAGAAG
TTGACGAGCGATTGATTGCGCAAGTGGTAGCTAATTGGACAGGGATTCCTGTGCAAAAAATGCTAGAAGGGGAAGCTGAG
AAACTGTTAATTCTTGAAGAATCCTTAGAAGAACGTGTGGTAGGACAGCCTTTTGCAGTCTCTGCGGTTAGTGATTCTAT
TCGTGCTGCACGTGTAGGTTTAAATGATCCTCAACGTCCCTTAGGAGTCTTTTTATTTTTAGGGCCAACAGGGGTAGGAA
AAACCGAGCTTGCAAAAGCTCTTGCAGATCTTCTTTTCAATAAAGAGGAAGCTATGGTCCGCTTCGATATGTCAGAGTAT
ATGGAAAAGCATTCCATTTCCAAGCTTATAGGATCTTCTCCAGGGTATGTGGGTTATGAGGAAGGTGGGAGTCTTTCTGA
GGCTCTTCGACGACGTCCCTATTCAGTAGTTCTCTTTGATGAGATAGAGAAAGCAGATAAGGAAGTTCTAAATATCCTTT
TACAGGTTTTTGATGATGGGATTCTTACGGATGGGAAAAAACGCAAAGTAAATTGTAAAAATGCCTTGTTTATCATGACA
TCAAATATAGGTTCTCCAGAACTTGCAGATTATTGTTCAAAAAAAGGAAGTGAGCTTACGAAAGAAGCGATTCTTTCTGT
AGTCTCTCCAGTATTGAAAAGATACTTGAGCCCTGAATTTATGAACCGAATTGATGAGATACTTCCTTTTGTTCCATTAA
CGAAAGAAGATATCGTGAAAATAGTTGGCATTCAAATGCGAAGGATTGCCCAGAGATTAAAGGCACGGCGGATCAATTTA
TCTTGGGATGATTCTGTAATATTATTTCTTAGTGAACAGGGTTATGACAGTGCTTTCGGAGCCCGCCCTTTAAAACGTTT
GATCCAACAAAAAGTTGTGATCTTGCTTTCTAAGGCTTTGCTTAAAGGAGATATTAAACCTGATACATCGATTGAGTTGA
CGATGGCAAAAGAGGTGCTCGTATTTAAAAAAGTGGAAACTCCTTCTTAG

Protein sequence :
MNFMEKFSDAVSEALEKAFELAKSSKHTYVTENHLLLALLENTESLFYLVIKDIHGNPGLLNTAVKDALSREPTVVEGEV
DPKPSPGLQTLLRDAKQEAKTLGDEYISGDHLLLAFWSSNKEPFNSWKQTTKVSFKDLKNLITKIRRGNRMDSPSAESNF
QGLEKYCKNLTALAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPMLIGEPGVGKTAIAEGLALRLIQGDVPESLKGKQLY
VLDMGALIAGAKYRGEFEERLKSVLKDVESGDGEHIIFIDEVHTLVGAGATDGAMDAANLLKPALARGTLHCIGATTLNE
YQKYIEKDAALERRFQPIFVTEPSLEDAVFILRGLREKYEIFHGVRITEGALNAAVLLSYRYIPDRFLPDKAIDLIDEAA
SLIRMQIGSLPLPIDEKERELAALIVKQEAIKREQSPSYQEEADAMQKSIDALREELASLRLGWDEEKKLISGLKEKKNS
LESMKFSEEEAERVADYNRVAELRYSLIPQLEEEIKQDEASLNQRDNRLLQEEVDERLIAQVVANWTGIPVQKMLEGEAE
KLLILEESLEERVVGQPFAVSAVSDSIRAARVGLNDPQRPLGVFLFLGPTGVGKTELAKALADLLFNKEEAMVRFDMSEY
MEKHSISKLIGSSPGYVGYEEGGSLSEALRRRPYSVVLFDEIEKADKEVLNILLQVFDDGILTDGKKRKVNCKNALFIMT
SNIGSPELADYCSKKGSELTKEAILSVVSPVLKRYLSPEFMNRIDEILPFVPLTKEDIVKIVGIQMRRIAQRLKARRINL
SWDDSVILFLSEQGYDSAFGARPLKRLIQQKVVILLSKALLKGDIKPDTSIELTMAKEVLVFKKVETPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-97 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CpB0145 NP_876421.1 ClpB VFG2084 Protein 1e-99 41
CpB0145 NP_876421.1 ClpB VFG2076 Protein 9e-114 41